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CRBN cereblon [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 704436, updated on 17-Aug-2024

Summary

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Official Symbol
CRBNprovided by VGNC
Official Full Name
cereblonprovided by VGNC
Primary source
VGNC:VGNC:71607
See related
Ensembl:ENSMMUG00000017986
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See CRBN in Genome Data Viewer
Location:
chromosome: 2
Exon count:
11
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 2 NC_041755.1 (134481753..134512704, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 2 NC_027894.1 (63389059..63418364)

Chromosome 2 - NC_041755.1Genomic Context describing neighboring genes Neighboring gene interleukin 5 receptor subunit alpha Neighboring gene uncharacterized LOC106996851 Neighboring gene tRNA nucleotidyl transferase 1 Neighboring gene uncharacterized LOC114676152 Neighboring gene uncharacterized LOC106996850

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Analysis of the Macaca mulatta transcriptome and the sequence divergence between Macaca and human. Magness CL, et al. Genome Biol, 2005. PMID 15998449, Free PMC Article
  2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in protein ubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of Cul4A-RING E3 ubiquitin ligase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
protein cereblon

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001195647.1 → NP_001182576.1  protein cereblon

    See identical proteins and their annotated locations for NP_001182576.1

    Status: VALIDATED

    Source sequence(s)
    CO579336, DQ147997, EG702761, QNVO02000283
    UniProtKB/TrEMBL
    A0A5F7ZMZ6, F7DSP3, H9FVB2
    Related
    ENSMMUP00000065991.1, ENSMMUT00000091357.1
    Conserved Domains (2) summary
    cd15777
    Location:321 → 422
    CRBN_C_like; Thalidomide-binding C-terminal domain of cereblon (CRBN) and similar protein domains
    pfam02190
    Location:80 → 317
    LON_substr_bdg; ATP-dependent protease La (LON) substrate-binding domain

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041755.1 Reference Mmul_10 Primary Assembly

    Range
    134481753..134512704 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028843227.1 → XP_028699060.1  protein cereblon isoform X1

    UniProtKB/TrEMBL
    A0A5F7ZMZ6, A0A5K1VSA6
    Related
    ENSMMUP00000023638.4, ENSMMUT00000025267.4
    Conserved Domains (2) summary
    cd15777
    Location:320 → 421
    CRBN_C_like; Thalidomide-binding C-terminal domain of cereblon (CRBN) and similar protein domains
    pfam02190
    Location:79 → 316
    LON_substr_bdg; ATP-dependent protease La (LON) substrate-binding domain
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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Research Materials