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Efcab3 EF-hand calcium binding domain 3 [ Mus musculus (house mouse) ]

Gene ID: 70894, updated on 2-Nov-2024

Summary

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Official Symbol
Efcab3provided by MGI
Official Full Name
EF-hand calcium binding domain 3provided by MGI
Primary source
MGI:MGI:1918144
See related
Ensembl:ENSMUSG00000020690 AllianceGenome:MGI:1918144
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm19; Efcab13; Efcab15; Gm11639; 4921510J17Rik
Summary
Predicted to enable calcium ion binding activity. Orthologous to human EFCAB3 (EF-hand calcium binding domain 3). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Restricted expression toward testis adult (RPKM 8.4) See more
Orthologs
human all
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Genomic context

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See Efcab3 in Genome Data Viewer
Location:
11 E1; 11
Exon count:
189
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (104576533..105008365)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (105008985..105117537)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer mm9_chr11:104469193-104469494 Neighboring gene STARR-positive B cell enhancer mm9_chr11:104483926-104484227 Neighboring gene STARR-positive B cell enhancer ABC_E1434 Neighboring gene integrin beta 3 Neighboring gene ribosomal protein L3 pseudogene Neighboring gene STARR-seq mESC enhancer starr_30895 Neighboring gene STARR-seq mESC enhancer starr_30896 Neighboring gene STARR-seq mESC enhancer starr_30897 Neighboring gene STARR-seq mESC enhancer starr_30898 Neighboring gene high mobility group box 2 pseudogene Neighboring gene STARR-seq mESC enhancer starr_30900 Neighboring gene STARR-seq mESC enhancer starr_30901 Neighboring gene predicted gene 11622 Neighboring gene microtubule-associated protein pseudogene Neighboring gene predicted gene, 25362 Neighboring gene STARR-positive B cell enhancer ABC_E7076 Neighboring gene methyltransferase 2, methylcytidine Neighboring gene predicted gene 11620

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Sixteen diverse laboratory mouse reference genomes define strain-specific haplotypes and novel functional loci. Lilue J, et al. Nat Genet, 2018 Nov. PMID 30275530, Free PMC Article
  2. Genome engineering uncovers 54 evolutionarily conserved and testis-enriched genes that are not required for male fertility in mice. Miyata H, et al. Proc Natl Acad Sci U S A, 2016 Jul 12. PMID 27357688, Free PMC Article
  3. Global discovery of erythroid long noncoding RNAs reveals novel regulators of red cell maturation. Alvarez-Dominguez JR, et al. Blood, 2014 Jan 23. PMID 24200680, Free PMC Article
  4. Widespread and dynamic translational control of red blood cell development. Alvarez-Dominguez JR, et al. Blood, 2017 Feb 2. PMID 27899360, Free PMC Article
  5. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 
  • Targeted (2)  1 citation

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
EF-hand calcium-binding domain-containing protein 3
Names
EF-hand calcium binding domain 13

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081046.2 → NP_001074515.1  EF-hand calcium-binding domain-containing protein 3 isoform 2

    See identical proteins and their annotated locations for NP_001074515.1

    Status: VALIDATED

    Source sequence(s)
    AL627235
    Consensus CDS
    CCDS36355.1
    UniProtKB/Swiss-Prot
    Q80X60
    Related
    ENSMUSP00000021029.6, ENSMUST00000021029.6
    Conserved Domains (2) summary
    PTZ00183
    Location:3 → 116
    PTZ00183; centrin; Provisional
    pfam13833
    Location:62 → 112
    EF-hand_8; EF-hand domain pair

  2. NM_001271338.1 → NP_001258267.1  EF-hand calcium-binding domain-containing protein 3 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL627235, AL645600, AL645725, AL645976, BX000996
    Related
    ENSMUSP00000148433.3, ENSMUST00000212287.3

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    104576533..105008365
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q80X60.1 GenPept UniProtKB/Swiss-Prot:Q80X60

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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