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STAT5B signal transducer and activator of transcription 5B [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 709760, updated on 17-Aug-2024

Summary

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Official Symbol
STAT5Bprovided by VGNC
Official Full Name
signal transducer and activator of transcription 5Bprovided by VGNC
Primary source
VGNC:VGNC:99275
See related
Ensembl:ENSMMUG00000003437
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See STAT5B in Genome Data Viewer
Location:
chromosome: 16
Exon count:
21
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 16 NC_041769.1 (53322391..53413152, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 16 NC_027908.1 (48060541..48126456, complement)

Chromosome 16 - NC_041769.1Genomic Context describing neighboring genes Neighboring gene hypocretin neuropeptide precursor Neighboring gene GH3 domain containing Neighboring gene signal transducer and activator of transcription 5A Neighboring gene signal transducer and activator of transcription 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor signaling pathway via JAK-STAT IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cytokine-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in defense response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in growth hormone receptor signaling pathway via JAK-STAT IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to peptide hormone IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
signal transducer and activator of transcription 5B

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041769.1 Reference Mmul_10 Primary Assembly

    Range
    53322391..53413152 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028836505.1 → XP_028692338.1  signal transducer and activator of transcription 5B isoform X1

    UniProtKB/TrEMBL
    F7F598, H9FYY3, H9FYY5
    Conserved Domains (4) summary
    cd10420
    Location:573 → 717
    SH2_STAT5b; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 5b proteins
    cd16855
    Location:139 → 330
    STAT5_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    cd16849
    Location:332 → 489
    STAT5_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    pfam02865
    Location:2 → 124
    STAT_int; STAT protein, protein interaction domain

  2. XM_028836506.1 → XP_028692339.1  signal transducer and activator of transcription 5B isoform X1

    UniProtKB/TrEMBL
    F7F598, H9FYY3, H9FYY5
    Related
    ENSMMUP00000058264.2, ENSMMUT00000075321.2
    Conserved Domains (4) summary
    cd10420
    Location:573 → 717
    SH2_STAT5b; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 5b proteins
    cd16855
    Location:139 → 330
    STAT5_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    cd16849
    Location:332 → 489
    STAT5_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    pfam02865
    Location:2 → 124
    STAT_int; STAT protein, protein interaction domain

  3. XM_028836504.1 → XP_028692337.1  signal transducer and activator of transcription 5B isoform X1

    UniProtKB/TrEMBL
    F7F598, H9FYY3, H9FYY5
    Related
    ENSMMUP00000004582.4, ENSMMUT00000004862.4
    Conserved Domains (4) summary
    cd10420
    Location:573 → 717
    SH2_STAT5b; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 5b proteins
    cd16855
    Location:139 → 330
    STAT5_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    cd16849
    Location:332 → 489
    STAT5_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    pfam02865
    Location:2 → 124
    STAT_int; STAT protein, protein interaction domain

  4. XM_028836507.1 → XP_028692340.1  signal transducer and activator of transcription 5B isoform X2

    UniProtKB/TrEMBL
    H9ZCU3
    Conserved Domains (4) summary
    cd10420
    Location:471 → 615
    SH2_STAT5b; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 5b proteins
    cd16855
    Location:37 → 228
    STAT5_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    cd16849
    Location:230 → 387
    STAT5_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    cl03749
    Location:1 → 22
    STAT_int; STAT protein, protein interaction domain
Nucleotide Protein
Heading Accession and Version

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