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HTRA2 HtrA serine peptidase 2 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 709938, updated on 17-Aug-2024

Summary

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Official Symbol
HTRA2provided by VGNC
Official Full Name
HtrA serine peptidase 2provided by VGNC
Primary source
VGNC:VGNC:73390
Locus tag
EGK_05477
See related
Ensembl:ENSMMUG00000002136
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See HTRA2 in Genome Data Viewer
Location:
chromosome: 13
Exon count:
17
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 13 NC_041766.1 (34283197..34289812, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 13 NC_027905.1 (75545411..75551908)

Chromosome 13 - NC_041766.1Genomic Context describing neighboring genes Neighboring gene meiosis 1 associated protein Neighboring gene torsin-1B-like Neighboring gene docking protein 1 Neighboring gene lysyl oxidase like 3 Neighboring gene AUP1 lipid droplet regulating VLDL assembly factor Neighboring gene DEAQ-box RNA dependent ATPase 1 Neighboring gene T cell leukemia homeobox 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
  2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in programmed cell death IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
serine protease HTRA2, mitochondrial
NP_001245067.1
XP_028687398.1
XP_028687399.1
XP_028687400.1
XP_028687401.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001258138.1 → NP_001245067.1  serine protease HTRA2, mitochondrial

    See identical proteins and their annotated locations for NP_001245067.1

    Status: PROVISIONAL

    Source sequence(s)
    JU475214
    UniProtKB/TrEMBL
    A0A8J8Y9R6, F6UNS8, G7NAF1
    Conserved Domains (1) summary
    TIGR02037
    Location:150 → 453
    degP_htrA_DO; periplasmic serine protease, Do/DeqQ family

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041766.1 Reference Mmul_10 Primary Assembly

    Range
    34283197..34289812 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028831568.1 → XP_028687401.1  serine protease HTRA2, mitochondrial isoform X4

    UniProtKB/TrEMBL
    F6UNR7, F6UNT9
    Related
    ENSMMUP00000002848.3, ENSMMUT00000003016.3
    Conserved Domains (1) summary
    TIGR02037
    Location:150 → 421
    degP_htrA_DO; periplasmic serine protease, Do/DeqQ family

  2. XM_028831567.1 → XP_028687400.1  serine protease HTRA2, mitochondrial isoform X3

    UniProtKB/TrEMBL
    A0A8J8Y9R6, F6UNS8, G7NAF1
    Related
    ENSMMUP00000073066.1, ENSMMUT00000100266.1
    Conserved Domains (1) summary
    TIGR02037
    Location:150 → 453
    degP_htrA_DO; periplasmic serine protease, Do/DeqQ family

  3. XM_028831565.1 → XP_028687398.1  serine protease HTRA2, mitochondrial isoform X1

    Conserved Domains (1) summary
    TIGR02037
    Location:150 → 528
    degP_htrA_DO; periplasmic serine protease, Do/DeqQ family

  4. XM_028831566.1 → XP_028687399.1  serine protease HTRA2, mitochondrial isoform X2

    Conserved Domains (1) summary
    TIGR02037
    Location:150 → 566
    degP_htrA_DO; periplasmic serine protease, Do/DeqQ family
Nucleotide Protein
Heading Accession and Version

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