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PDE8B phosphodiesterase 8B [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 712674, updated on 5-Mar-2024

Summary

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Gene symbol
PDE8B
Gene description
phosphodiesterase 8B
See related
Ensembl:ENSMMUG00000021358
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See PDE8B in Genome Data Viewer
Location:
chromosome: 6
Exon count:
25
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 6 NC_041759.1 (73911957..74255819)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 6 NC_027898.1 (73892355..74104933)

Chromosome 6 - NC_041759.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA47 Neighboring gene angiogenic factor with G-patch and FHA domains 1 Neighboring gene zinc finger BED-type containing 3 Neighboring gene uncharacterized LOC114678825 Neighboring gene WD repeat domain 41 Neighboring gene 60S ribosomal protein L23a pseudogene Neighboring gene orthopedia homeobox

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 3',5'-cyclic-AMP phosphodiesterase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041759.1 Reference Mmul_10 Primary Assembly

    Range
    73911957..74255819
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028849529.1 → XP_028705362.1  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X8

    UniProtKB/TrEMBL
    G7MUT5
    Related
    ENSMMUP00000061042.2, ENSMMUT00000077405.2
    Conserved Domains (3) summary
    COG2202
    Location:24 → 254
    PAS; PAS domain [Signal transduction mechanisms]
    pfam00233
    Location:490 → 737
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
    pfam13426
    Location:156 → 253
    PAS_9; PAS domain

  2. XM_028849528.1 → XP_028705361.1  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X7

    UniProtKB/TrEMBL
    G7MUT5
    Related
    ENSMMUP00000048595.2, ENSMMUT00000076848.2
    Conserved Domains (3) summary
    COG2202
    Location:47 → 274
    PAS; PAS domain [Signal transduction mechanisms]
    pfam00233
    Location:513 → 760
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
    pfam13426
    Location:179 → 276
    PAS_9; PAS domain

  3. XM_028849527.1 → XP_028705360.1  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X5

    Conserved Domains (4) summary
    COG2202
    Location:401 → 612
    PAS; PAS domain [Signal transduction mechanisms]
    pfam08629
    Location:235 → 281
    PDE8; PDE8 phosphodiesterase
    pfam00233
    Location:848 → 1039
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
    pfam13426
    Location:514 → 611
    PAS_9; PAS domain

  4. XM_015140308.2 → XP_014995794.2  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X4

    Conserved Domains (4) summary
    COG2202
    Location:382 → 551
    PAS; PAS domain [Signal transduction mechanisms]
    pfam08629
    Location:235 → 281
    PDE8; PDE8 phosphodiesterase
    pfam00233
    Location:798 → 1045
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
    pfam13426
    Location:514 → 567
    PAS_9; PAS domain

  5. XM_015140305.2 → XP_014995791.2  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X1

    UniProtKB/TrEMBL
    A0A1D5QWH4
    Related
    ENSMMUP00000052404.2, ENSMMUT00000064805.2
    Conserved Domains (4) summary
    COG2202
    Location:382 → 612
    PAS; PAS domain [Signal transduction mechanisms]
    pfam08629
    Location:235 → 281
    PDE8; PDE8 phosphodiesterase
    pfam00233
    Location:848 → 1095
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
    pfam13426
    Location:514 → 611
    PAS_9; PAS domain

  6. XM_015140306.2 → XP_014995792.2  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X2

    Conserved Domains (4) summary
    COG2202
    Location:381 → 611
    PAS; PAS domain [Signal transduction mechanisms]
    pfam08629
    Location:235 → 281
    PDE8; PDE8 phosphodiesterase
    pfam00233
    Location:847 → 1094
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
    pfam13426
    Location:513 → 610
    PAS_9; PAS domain

  7. XM_015140307.2 → XP_014995793.2  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X3

    UniProtKB/TrEMBL
    A0A1D5RFF8
    Related
    ENSMMUP00000059052.2, ENSMMUT00000069291.2
    Conserved Domains (2) summary
    pfam08629
    Location:235 → 281
    PDE8; PDE8 phosphodiesterase
    pfam00233
    Location:801 → 1048
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase

  8. XM_015140309.2 → XP_014995795.2  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X6

    UniProtKB/TrEMBL
    F7DG52
    Related
    ENSMMUP00000028138.4, ENSMMUT00000030066.4
    Conserved Domains (3) summary
    PHA02597
    Location:392 → 545
    30.2; hypothetical protein; Provisional
    pfam08629
    Location:235 → 281
    PDE8; PDE8 phosphodiesterase
    pfam00233
    Location:751 → 998
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
Nucleotide Protein
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