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Lrrfip2 leucine rich repeat (in FLII) interacting protein 2 [ Mus musculus (house mouse) ]

Gene ID: 71268, updated on 2-Nov-2024

Summary

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Official Symbol
Lrrfip2provided by MGI
Official Full Name
leucine rich repeat (in FLII) interacting protein 2provided by MGI
Primary source
MGI:MGI:1918518
See related
Ensembl:ENSMUSG00000032497 AllianceGenome:MGI:1918518
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
5133400F20Rik
Summary
Predicted to enable LRR domain binding activity. Acts upstream of or within regulation of gene expression and toll-like receptor signaling pathway. Is expressed in 1st branchial arch mandibular component mesenchyme; craniocervical region bone; and facial prominence. Orthologous to human LRRFIP2 (LRR binding FLII interacting protein 2). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in testis adult (RPKM 12.8), placenta adult (RPKM 9.9) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Lrrfip2 in Genome Data Viewer
Location:
9 F3; 9 60.92 cM
Exon count:
33
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (110946614..111054736)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (111117546..111225668)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_25286 Neighboring gene ribosomal protein L31, pseudogene 19 Neighboring gene predicted gene, 26409 Neighboring gene predicted gene, 53519 Neighboring gene STARR-seq mESC enhancer starr_25288 Neighboring gene predicted gene, 57536 Neighboring gene predicted gene, 51692 Neighboring gene mutL homolog 1 Neighboring gene CapStarr-seq enhancer MGSCv37_chr9:111177746-111177899 Neighboring gene EPM2A interacting protein 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Unambiguous characterization of site-specific phosphorylation of leucine-rich repeat Fli-I-interacting protein 2 (LRRFIP2) in Toll-like receptor 4 (TLR4)-mediated signaling. Gunawardena HP, et al. J Biol Chem, 2011 Apr 1. PMID 21220426, Free PMC Article
  2. LRRFIP2 negatively regulates NLRP3 inflammasome activation in macrophages by promoting Flightless-I-mediated caspase-1 inhibition. Jin J, et al. Nat Commun, 2013. PMID 23942110, Free PMC Article
  3. Modulation of TLR signaling by multiple MyD88-interacting partners including leucine-rich repeat Fli-I-interacting proteins. Dai P, et al. J Immunol, 2009 Mar 15. PMID 19265123
  4. In vivo dual-tagging proteomic approach in studying signaling pathways in immune response. Wang T, et al. J Proteome Res, 2005 May-Jun. PMID 15952741
  5. An Alternative Splicing Program for Mouse Craniofacial Development. Hooper JE, et al. Front Physiol, 2020. PMID 33013468, Free PMC Article

See all (33) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. LRRFIP2 inhibits NLRP3 inflammasome activation by recruiting the caspase-1 inhibitor Flightless-I, thus outlining a new mechanism for negative regulation of NLRP3 inflammasome.
    Title: LRRFIP2 negatively regulates NLRP3 inflammasome activation in macrophages by promoting Flightless-I-mediated caspase-1 inhibition.
  2. Unambiguous characterization of site-specific phosphorylation of leucine-rich repeat Fli-I-interacting protein 2 (LRRFIP2) in Toll-like receptor 4 (TLR4)-mediated signaling.
    Title: Unambiguous characterization of site-specific phosphorylation of leucine-rich repeat Fli-I-interacting protein 2 (LRRFIP2) in Toll-like receptor 4 (TLR4)-mediated signaling.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables LRR domain binding ISO
Inferred from Sequence Orthology
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within MyD88-dependent toll-like receptor 4 signaling pathway IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within MyD88-independent toll-like receptor signaling pathway IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within positive regulation of NF-kappaB transcription factor activity IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within positive regulation of NF-kappaB transcription factor activity IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within positive regulation of NF-kappaB transcription factor activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within positive regulation of tumor necrosis factor production IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
leucine-rich repeat flightless-interacting protein 2
Names
LRR FLII-interacting protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001164838.1 → NP_001158310.1  leucine-rich repeat flightless-interacting protein 2 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes isoform 1.
    Source sequence(s)
    AC132832, AK078881, BY346593
    Consensus CDS
    CCDS52941.1
    UniProtKB/Swiss-Prot
    Q8BVD1, Q91WK0, Q9CU89
    UniProtKB/TrEMBL
    E9QN52
    Related
    ENSMUSP00000035078.7, ENSMUST00000035078.13
    Conserved Domains (2) summary
    pfam04111
    Location:311 → 405
    APG6; Autophagy protein Apg6
    pfam09738
    Location:47 → 340
    LRRFIP; LRRFIP family

  2. NM_001374664.1 → NP_001361593.1  leucine-rich repeat flightless-interacting protein 2 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC132832
    Consensus CDS
    CCDS90673.1
    UniProtKB/Swiss-Prot
    Q8BVD1, Q91WK0, Q9CU89
    UniProtKB/TrEMBL
    A0A0G2JEP4
    Related
    ENSMUSP00000142851.2, ENSMUST00000196981.5
    Conserved Domains (2) summary
    pfam09738
    Location:47 → 349
    LRRFIP; LRRFIP family
    pfam11932
    Location:365 → 424
    DUF3450; Protein of unknown function (DUF3450)

  3. NM_027742.3 → NP_082018.1  leucine-rich repeat flightless-interacting protein 2 isoform 2

    See identical proteins and their annotated locations for NP_082018.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an exon in the 5' coding region compared to variant 1 but maintains the reading frame. The resulting protein (isoform 2) is shorter than isoform 1.
    Source sequence(s)
    AC132832, AK078881, BY346593
    Consensus CDS
    CCDS23583.1
    UniProtKB/Swiss-Prot
    Q8BVD1, Q91WK0, Q9CU89
    UniProtKB/TrEMBL
    A0A0R4J169
    Related
    ENSMUSP00000095944.3, ENSMUST00000098340.7
    Conserved Domains (2) summary
    pfam04111
    Location:296 → 390
    APG6; Autophagy protein Apg6
    pfam09738
    Location:47 → 325
    LRRFIP; LRRFIP family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    110946614..111054736
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011243000.3 → XP_011241302.1  leucine-rich repeat flightless-interacting protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A668KLE1
    Conserved Domains (3) summary
    TIGR04211
    Location:465 → 549
    SH3_and_anchor; SH3 domain protein
    pfam09738
    Location:319 → 673
    LRRFIP; LRRFIP family
    pfam11932
    Location:689 → 748
    DUF3450; Protein of unknown function (DUF3450)

  2. XM_036155284.1 → XP_036011177.1  leucine-rich repeat flightless-interacting protein 2 isoform X7

    UniProtKB/TrEMBL
    A0A668KLE1
    Conserved Domains (2) summary
    pfam09738
    Location:319 → 642
    LRRFIP; LRRFIP family
    pfam11932
    Location:658 → 717
    DUF3450; Protein of unknown function (DUF3450)

  3. XM_017313589.3 → XP_017169078.1  leucine-rich repeat flightless-interacting protein 2 isoform X15

    UniProtKB/TrEMBL
    A0A668KLE1
    Conserved Domains (2) summary
    pfam09738
    Location:319 → 608
    LRRFIP; LRRFIP family
    pfam11932
    Location:624 → 683
    DUF3450; Protein of unknown function (DUF3450)

  4. XM_011243004.3 → XP_011241306.1  leucine-rich repeat flightless-interacting protein 2 isoform X5

    UniProtKB/TrEMBL
    A0A668KLE1
    Conserved Domains (3) summary
    TIGR04211
    Location:441 → 525
    SH3_and_anchor; SH3 domain protein
    pfam09738
    Location:319 → 649
    LRRFIP; LRRFIP family
    pfam11932
    Location:665 → 724
    DUF3450; Protein of unknown function (DUF3450)

  5. XM_017313590.3 → XP_017169079.1  leucine-rich repeat flightless-interacting protein 2 isoform X17

    UniProtKB/TrEMBL
    A0A668KLE1
    Conserved Domains (2) summary
    pfam09738
    Location:319 → 584
    LRRFIP; LRRFIP family
    pfam11932
    Location:600 → 659
    DUF3450; Protein of unknown function (DUF3450)

  6. XM_036155286.1 → XP_036011179.1  leucine-rich repeat flightless-interacting protein 2 isoform X14

    UniProtKB/TrEMBL
    A0A668KLE1
    Conserved Domains (2) summary
    pfam09738
    Location:286 → 609
    LRRFIP; LRRFIP family
    pfam11932
    Location:625 → 684
    DUF3450; Protein of unknown function (DUF3450)

  7. XM_030244586.1 → XP_030100446.1  leucine-rich repeat flightless-interacting protein 2 isoform X16

    UniProtKB/TrEMBL
    A0A668KLE1
    Conserved Domains (2) summary
    pfam09738
    Location:301 → 600
    LRRFIP; LRRFIP family
    pfam11932
    Location:616 → 675
    DUF3450; Protein of unknown function (DUF3450)

  8. XM_036155287.1 → XP_036011180.1  leucine-rich repeat flightless-interacting protein 2 isoform X22

    Conserved Domains (2) summary
    pfam09738
    Location:196 → 485
    LRRFIP; LRRFIP family
    pfam11932
    Location:501 → 560
    DUF3450; Protein of unknown function (DUF3450)

  9. XM_030244588.2 → XP_030100448.1  leucine-rich repeat flightless-interacting protein 2 isoform X24

    UniProtKB/TrEMBL
    A0A0G2JFV5
    Conserved Domains (2) summary
    pfam09738
    Location:196 → 461
    LRRFIP; LRRFIP family
    pfam11932
    Location:477 → 536
    DUF3450; Protein of unknown function (DUF3450)

  10. XM_030244589.1 → XP_030100449.1  leucine-rich repeat flightless-interacting protein 2 isoform X26

    Conserved Domains (2) summary
    pfam09738
    Location:47 → 435
    LRRFIP; LRRFIP family
    pfam11932
    Location:451 → 510
    DUF3450; Protein of unknown function (DUF3450)

  11. XM_030244591.1 → XP_030100451.1  leucine-rich repeat flightless-interacting protein 2 isoform X31

    Conserved Domains (2) summary
    pfam09738
    Location:47 → 411
    LRRFIP; LRRFIP family
    pfam11932
    Location:427 → 486
    DUF3450; Protein of unknown function (DUF3450)

  12. XM_011243024.3 → XP_011241326.1  leucine-rich repeat flightless-interacting protein 2 isoform X32

    Conserved Domains (3) summary
    TIGR04211
    Location:197 → 281
    SH3_and_anchor; SH3 domain protein
    pfam05266
    Location:380 → 454
    DUF724; Protein of unknown function (DUF724)
    pfam09738
    Location:47 → 405
    LRRFIP; LRRFIP family

  13. XM_011243026.3 → XP_011241328.1  leucine-rich repeat flightless-interacting protein 2 isoform X43

    UniProtKB/TrEMBL
    A0A1L1SSC0
    Conserved Domains (2) summary
    pfam09738
    Location:267 → 532
    LRRFIP; LRRFIP family
    pfam11932
    Location:548 → 607
    DUF3450; Protein of unknown function (DUF3450)

  14. XM_030244587.2 → XP_030100447.1  leucine-rich repeat flightless-interacting protein 2 isoform X20

    UniProtKB/TrEMBL
    A0A1L1SSC0
    Conserved Domains (2) summary
    pfam09738
    Location:200 → 489
    LRRFIP; LRRFIP family
    pfam11932
    Location:505 → 564
    DUF3450; Protein of unknown function (DUF3450)

  15. XM_036155288.1 → XP_036011181.1  leucine-rich repeat flightless-interacting protein 2 isoform X35

    Conserved Domains (2) summary
    pfam09738
    Location:47 → 380
    LRRFIP; LRRFIP family
    pfam11932
    Location:396 → 455
    DUF3450; Protein of unknown function (DUF3450)

  16. XM_017313591.3 → XP_017169080.1  leucine-rich repeat flightless-interacting protein 2 isoform X34

    Conserved Domains (2) summary
    pfam05266
    Location:358 → 432
    DUF724; Protein of unknown function (DUF724)
    pfam09738
    Location:47 → 383
    LRRFIP; LRRFIP family

  17. XM_030244593.1 → XP_030100453.1  leucine-rich repeat flightless-interacting protein 2 isoform X33

    Conserved Domains (3) summary
    TIGR04211
    Location:182 → 266
    SH3_and_anchor; SH3 domain protein
    pfam05266
    Location:365 → 439
    DUF724; Protein of unknown function (DUF724)
    pfam09738
    Location:47 → 390
    LRRFIP; LRRFIP family

  18. XM_036155289.1 → XP_036011182.1  leucine-rich repeat flightless-interacting protein 2 isoform X39

    Conserved Domains (2) summary
    pfam09738
    Location:47 → 356
    LRRFIP; LRRFIP family
    pfam11932
    Location:372 → 431
    DUF3450; Protein of unknown function (DUF3450)

  19. XM_030244596.1 → XP_030100456.1  leucine-rich repeat flightless-interacting protein 2 isoform X38

    Conserved Domains (2) summary
    pfam09738
    Location:47 → 359
    LRRFIP; LRRFIP family
    pfam11932
    Location:375 → 434
    DUF3450; Protein of unknown function (DUF3450)

  20. XM_011243001.4 → XP_011241303.1  leucine-rich repeat flightless-interacting protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A668KLE1
    Related
    ENSMUSP00000159250.2, ENSMUST00000239186.2
    Conserved Domains (3) summary
    TIGR04211
    Location:462 → 546
    SH3_and_anchor; SH3 domain protein
    pfam09738
    Location:316 → 670
    LRRFIP; LRRFIP family
    pfam11932
    Location:686 → 745
    DUF3450; Protein of unknown function (DUF3450)

  21. XM_036155285.1 → XP_036011178.1  leucine-rich repeat flightless-interacting protein 2 isoform X9

    UniProtKB/TrEMBL
    A0A668KLE1
    Conserved Domains (2) summary
    pfam09738
    Location:286 → 640
    LRRFIP; LRRFIP family
    pfam11932
    Location:656 → 715
    DUF3450; Protein of unknown function (DUF3450)

  22. XM_011243005.4 → XP_011241307.1  leucine-rich repeat flightless-interacting protein 2 isoform X6

    UniProtKB/TrEMBL
    A0A668KLE1
    Conserved Domains (3) summary
    TIGR04211
    Location:439 → 523
    SH3_and_anchor; SH3 domain protein
    pfam09738
    Location:293 → 647
    LRRFIP; LRRFIP family
    pfam11932
    Location:663 → 722
    DUF3450; Protein of unknown function (DUF3450)

  23. XM_011243012.4 → XP_011241314.1  leucine-rich repeat flightless-interacting protein 2 isoform X13

    UniProtKB/TrEMBL
    A0A668KLE1
    Conserved Domains (3) summary
    TIGR04211
    Location:409 → 493
    SH3_and_anchor; SH3 domain protein
    pfam09738
    Location:263 → 617
    LRRFIP; LRRFIP family
    pfam11932
    Location:633 → 692
    DUF3450; Protein of unknown function (DUF3450)

  24. XM_011243003.4 → XP_011241305.1  leucine-rich repeat flightless-interacting protein 2 isoform X4

    UniProtKB/TrEMBL
    A0A668KLE1
    Conserved Domains (3) summary
    TIGR04211
    Location:446 → 530
    SH3_and_anchor; SH3 domain protein
    pfam09738
    Location:300 → 654
    LRRFIP; LRRFIP family
    pfam11932
    Location:670 → 729
    DUF3450; Protein of unknown function (DUF3450)

  25. XM_011243002.4 → XP_011241304.1  leucine-rich repeat flightless-interacting protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A668KLE1
    Conserved Domains (3) summary
    TIGR04211
    Location:450 → 534
    SH3_and_anchor; SH3 domain protein
    pfam09738
    Location:304 → 658
    LRRFIP; LRRFIP family
    pfam11932
    Location:674 → 733
    DUF3450; Protein of unknown function (DUF3450)

  26. XM_011243008.4 → XP_011241310.1  leucine-rich repeat flightless-interacting protein 2 isoform X10

    UniProtKB/TrEMBL
    A0A668KLE1
    Conserved Domains (3) summary
    TIGR04211
    Location:431 → 515
    SH3_and_anchor; SH3 domain protein
    pfam09738
    Location:285 → 639
    LRRFIP; LRRFIP family
    pfam11932
    Location:655 → 714
    DUF3450; Protein of unknown function (DUF3450)

  27. XM_011243007.4 → XP_011241309.1  leucine-rich repeat flightless-interacting protein 2 isoform X8

    UniProtKB/TrEMBL
    A0A668KLE1
    Conserved Domains (3) summary
    TIGR04211
    Location:433 → 517
    SH3_and_anchor; SH3 domain protein
    pfam09738
    Location:287 → 641
    LRRFIP; LRRFIP family
    pfam11932
    Location:657 → 716
    DUF3450; Protein of unknown function (DUF3450)

  28. XM_011243016.4 → XP_011241318.1  leucine-rich repeat flightless-interacting protein 2 isoform X18

    UniProtKB/TrEMBL
    A0A668KLE1
    Conserved Domains (3) summary
    TIGR04211
    Location:342 → 426
    SH3_and_anchor; SH3 domain protein
    pfam09738
    Location:196 → 550
    LRRFIP; LRRFIP family
    pfam11932
    Location:566 → 625
    DUF3450; Protein of unknown function (DUF3450)

  29. XM_011243017.4 → XP_011241319.1  leucine-rich repeat flightless-interacting protein 2 isoform X19

    UniProtKB/TrEMBL
    A0A668KLE1
    Conserved Domains (3) summary
    TIGR04211
    Location:337 → 421
    SH3_and_anchor; SH3 domain protein
    pfam09738
    Location:191 → 545
    LRRFIP; LRRFIP family
    pfam11932
    Location:561 → 620
    DUF3450; Protein of unknown function (DUF3450)

  30. XM_011243018.4 → XP_011241320.1  leucine-rich repeat flightless-interacting protein 2 isoform X21

    UniProtKB/TrEMBL
    A0A1L1SSC0
    Conserved Domains (3) summary
    TIGR04211
    Location:281 → 365
    SH3_and_anchor; SH3 domain protein
    pfam09738
    Location:135 → 489
    LRRFIP; LRRFIP family
    pfam11932
    Location:505 → 564
    DUF3450; Protein of unknown function (DUF3450)

  31. XM_011243019.4 → XP_011241321.1  leucine-rich repeat flightless-interacting protein 2 isoform X23

    UniProtKB/TrEMBL
    A0A1L1SSC0
    Conserved Domains (3) summary
    TIGR04211
    Location:258 → 342
    SH3_and_anchor; SH3 domain protein
    pfam09738
    Location:47 → 466
    LRRFIP; LRRFIP family
    pfam11932
    Location:482 → 541
    DUF3450; Protein of unknown function (DUF3450)

  32. XM_011243010.4 → XP_011241312.1  leucine-rich repeat flightless-interacting protein 2 isoform X11

    UniProtKB/TrEMBL
    A0A1L1SSC0
    Conserved Domains (3) summary
    TIGR04211
    Location:428 → 512
    SH3_and_anchor; SH3 domain protein
    pfam09738
    Location:282 → 636
    LRRFIP; LRRFIP family
    pfam11932
    Location:652 → 711
    DUF3450; Protein of unknown function (DUF3450)

  33. XM_011243021.4 → XP_011241323.1  leucine-rich repeat flightless-interacting protein 2 isoform X27

    Conserved Domains (3) summary
    TIGR04211
    Location:221 → 305
    SH3_and_anchor; SH3 domain protein
    pfam05266
    Location:404 → 478
    DUF724; Protein of unknown function (DUF724)
    pfam09738
    Location:47 → 429
    LRRFIP; LRRFIP family

  34. XM_011243011.4 → XP_011241313.1  leucine-rich repeat flightless-interacting protein 2 isoform X12

    UniProtKB/TrEMBL
    A0A1L1SSC0
    Related
    ENSMUSP00000149845.3, ENSMUST00000217341.3
    Conserved Domains (3) summary
    TIGR04211
    Location:413 → 497
    SH3_and_anchor; SH3 domain protein
    pfam09738
    Location:267 → 621
    LRRFIP; LRRFIP family
    pfam11932
    Location:637 → 696
    DUF3450; Protein of unknown function (DUF3450)

  35. XM_011243020.4 → XP_011241322.1  leucine-rich repeat flightless-interacting protein 2 isoform X25

    Conserved Domains (3) summary
    TIGR04211
    Location:229 → 313
    SH3_and_anchor; SH3 domain protein
    pfam05266
    Location:412 → 486
    DUF724; Protein of unknown function (DUF724)
    pfam09738
    Location:47 → 437
    LRRFIP; LRRFIP family

  36. XM_011243023.4 → XP_011241325.1  leucine-rich repeat flightless-interacting protein 2 isoform X30

    Conserved Domains (3) summary
    TIGR04211
    Location:206 → 290
    SH3_and_anchor; SH3 domain protein
    pfam05266
    Location:389 → 463
    DUF724; Protein of unknown function (DUF724)
    pfam09738
    Location:47 → 414
    LRRFIP; LRRFIP family

  37. XM_011243022.4 → XP_011241324.1  leucine-rich repeat flightless-interacting protein 2 isoform X28

    Conserved Domains (1) summary
    pfam09738
    Location:319 → 484
    LRRFIP; LRRFIP family

  38. XM_006512287.4 → XP_006512350.1  leucine-rich repeat flightless-interacting protein 2 isoform X29

    Conserved Domains (3) summary
    TIGR04211
    Location:212 → 296
    SH3_and_anchor; SH3 domain protein
    pfam05266
    Location:395 → 469
    DUF724; Protein of unknown function (DUF724)
    pfam09738
    Location:66 → 420
    LRRFIP; LRRFIP family

  39. XM_030244598.2 → XP_030100458.1  leucine-rich repeat flightless-interacting protein 2 isoform X41

    UniProtKB/TrEMBL
    A0A1L1SQW1
    Related
    ENSMUSP00000149212.2, ENSMUST00000216430.2
    Conserved Domains (2) summary
    pfam09738
    Location:36 → 301
    LRRFIP; LRRFIP family
    pfam11932
    Location:317 → 376
    DUF3450; Protein of unknown function (DUF3450)

  40. XM_030244595.2 → XP_030100455.1  leucine-rich repeat flightless-interacting protein 2 isoform X37

    UniProtKB/TrEMBL
    Q8C062
    Related
    ENSMUST00000197540.5
    Conserved Domains (3) summary
    TIGR04211
    Location:155 → 239
    SH3_and_anchor; SH3 domain protein
    pfam05266
    Location:338 → 412
    DUF724; Protein of unknown function (DUF724)
    pfam09738
    Location:33 → 363
    LRRFIP; LRRFIP family

  41. XM_030244599.2 → XP_030100459.1  leucine-rich repeat flightless-interacting protein 2 isoform X42

    UniProtKB/TrEMBL
    A0A1L1SQW1, A0A1L1SVG1
    Related
    ENSMUSP00000151145.2, ENSMUST00000217117.2
    Conserved Domains (2) summary
    pfam09738
    Location:33 → 298
    LRRFIP; LRRFIP family
    pfam11932
    Location:314 → 373
    DUF3450; Protein of unknown function (DUF3450)

  42. XM_030244597.1 → XP_030100457.1  leucine-rich repeat flightless-interacting protein 2 isoform X40

    UniProtKB/TrEMBL
    Q8C062
    Conserved Domains (2) summary
    pfam09738
    Location:13 → 309
    LRRFIP; LRRFIP family
    pfam11932
    Location:325 → 384
    DUF3450; Protein of unknown function (DUF3450)

  43. XM_006512290.2 → XP_006512353.1  leucine-rich repeat flightless-interacting protein 2 isoform X36

    UniProtKB/TrEMBL
    Q8C062
    Conserved Domains (3) summary
    TIGR04211
    Location:159 → 243
    SH3_and_anchor; SH3 domain protein
    pfam05266
    Location:342 → 416
    DUF724; Protein of unknown function (DUF724)
    pfam09738
    Location:13 → 367
    LRRFIP; LRRFIP family
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q91WK0.1 GenPept UniProtKB/Swiss-Prot:Q91WK0

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