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PLEKHH2 pleckstrin homology, MyTH4 and FERM domain containing H2 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 713488, updated on 17-Aug-2024

Summary

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Official Symbol
PLEKHH2provided by VGNC
Official Full Name
pleckstrin homology, MyTH4 and FERM domain containing H2provided by VGNC
Primary source
VGNC:VGNC:76146
Locus tag
EGK_05282
See related
Ensembl:ENSMMUG00000008074
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See PLEKHH2 in Genome Data Viewer
Location:
chromosome: 13
Exon count:
31
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 13 NC_041766.1 (65035035..65159845, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 13 NC_027905.1 (44318097..44489585)

Chromosome 13 - NC_041766.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106992923 Neighboring gene ATP binding cassette subfamily G member 5 Neighboring gene dynein cytoplasmic 2 light intermediate chain 1 Neighboring gene uncharacterized LOC106992922 Neighboring gene 40S ribosomal protein S2 pseudogene Neighboring gene C1GALT1 specific chaperone 1 like Neighboring gene THADA armadillo repeat containing Neighboring gene U6 spliceosomal RNA Neighboring gene ZFP36 ring finger protein like 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables actin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of actin filament depolymerization IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
pleckstrin homology domain-containing family H member 2
Names
pleckstrin homology domain-containing family H member 2-like

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041766.1 Reference Mmul_10 Primary Assembly

    Range
    65035035..65159845 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015112245.2 → XP_014967731.1  pleckstrin homology domain-containing family H member 2 isoform X1

    UniProtKB/TrEMBL
    A0A5F7ZEK0, A0A663D7H1, A0A8J8YJR5, F6ZRY3, G7N9Y9
    Related
    ENSMMUP00000036575.2, ENSMMUT00000043574.3
    Conserved Domains (7) summary
    smart00139
    Location:955 → 1110
    MyTH4; Domain in Myosin and Kinesin Tails
    smart00295
    Location:1123 → 1354
    B41; Band 4.1 homologues
    cd13206
    Location:1350 → 1449
    FERM_C-lobe_PLEKHH1_PLEKHH2; FERM domain C-lobe of Pleckstrin homology domain-containing family H
    cd13282
    Location:706 → 801
    PH1_PLEKHH1_PLEKHH2; Pleckstrin homology (PH) domain containing, family H (with MyTH4 domain) members 1 and 2 (PLEKHH1) PH domain, repeat 1
    pfam00169
    Location:704 → 797
    PH; PH domain
    cl09511
    Location:1229 → 1354
    FERM_B-lobe; FERM domain B-lobe
    cl17171
    Location:816 → 873
    PH-like; Pleckstrin homology-like domain

  2. XM_028831707.1 → XP_028687540.1  pleckstrin homology domain-containing family H member 2 isoform X2

    UniProtKB/TrEMBL
    A0A5F7ZBL4, A0A5F7ZEK0
    Related
    ENSMMUP00000062973.1, ENSMMUT00000079273.1
    Conserved Domains (8) summary
    smart00139
    Location:914 → 1069
    MyTH4; Domain in Myosin and Kinesin Tails
    smart00295
    Location:1082 → 1313
    B41; Band 4.1 homologues
    PRK12704
    Location:1 → 92
    PRK12704; phosphodiesterase; Provisional
    cd13206
    Location:1309 → 1408
    FERM_C-lobe_PLEKHH1_PLEKHH2; FERM domain C-lobe of Pleckstrin homology domain-containing family H
    cd13282
    Location:665 → 760
    PH1_PLEKHH1_PLEKHH2; Pleckstrin homology (PH) domain containing, family H (with MyTH4 domain) members 1 and 2 (PLEKHH1) PH domain, repeat 1
    pfam02463
    Location:4 → 203
    SMC_N; RecF/RecN/SMC N terminal domain
    cd17179
    Location:1079 → 1181
    FERM_F1_PLEKHH2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in pleckstrin homology domain-containing family H member 2 (PLEKHH2)
    cl17171
    Location:775 → 832
    PH-like; Pleckstrin homology-like domain

  3. XM_028831706.1 → XP_028687539.1  pleckstrin homology domain-containing family H member 2 isoform X2

    UniProtKB/TrEMBL
    A0A5F7ZBL4, A0A5F7ZEK0
    Conserved Domains (8) summary
    smart00139
    Location:914 → 1069
    MyTH4; Domain in Myosin and Kinesin Tails
    smart00295
    Location:1082 → 1313
    B41; Band 4.1 homologues
    PRK12704
    Location:1 → 92
    PRK12704; phosphodiesterase; Provisional
    cd13206
    Location:1309 → 1408
    FERM_C-lobe_PLEKHH1_PLEKHH2; FERM domain C-lobe of Pleckstrin homology domain-containing family H
    cd13282
    Location:665 → 760
    PH1_PLEKHH1_PLEKHH2; Pleckstrin homology (PH) domain containing, family H (with MyTH4 domain) members 1 and 2 (PLEKHH1) PH domain, repeat 1
    pfam02463
    Location:4 → 203
    SMC_N; RecF/RecN/SMC N terminal domain
    cd17179
    Location:1079 → 1181
    FERM_F1_PLEKHH2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in pleckstrin homology domain-containing family H member 2 (PLEKHH2)
    cl17171
    Location:775 → 832
    PH-like; Pleckstrin homology-like domain
Nucleotide Protein
Heading Accession and Version

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