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MAP3K3 mitogen-activated protein kinase kinase kinase 3 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 717866, updated on 17-Aug-2024

Summary

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Official Symbol
MAP3K3provided by VGNC
Official Full Name
mitogen-activated protein kinase kinase kinase 3provided by VGNC
Primary source
VGNC:VGNC:81462
See related
Ensembl:ENSMMUG00000016751
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See MAP3K3 in Genome Data Viewer
Location:
chromosome: 16
Exon count:
19
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 16 NC_041769.1 (60072729..60147828)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 16 NC_027908.1 (57229656..57304903)

Chromosome 16 - NC_041769.1Genomic Context describing neighboring genes Neighboring gene translational activator of cytochrome c oxidase I Neighboring gene protein FAM136A pseudogene Neighboring gene LIM domain containing 2 Neighboring gene STE20 related adaptor alpha

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
mitogen-activated protein kinase kinase kinase 3
NP_001244715.1
XP_014975537.1
XP_014975538.1
XP_014975539.1
XP_014975540.2
XP_028691593.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001257786.1 → NP_001244715.1  mitogen-activated protein kinase kinase kinase 3

    See identical proteins and their annotated locations for NP_001244715.1

    Status: PROVISIONAL

    Source sequence(s)
    JU334556
    UniProtKB/TrEMBL
    A0A1D5QJ66, F7AIB6
    Related
    ENSMMUP00000048089.1, ENSMMUT00000075594.2
    Conserved Domains (2) summary
    cd06405
    Location:76 → 154
    PB1_Mekk2_3; The PB1 domain is present in the two mitogen-activated protein kinase kinases MEKK2 and MEKK3 which are two members of the signaling kinase cascade involved in angiogenesis and early cardiovascular development. The PB1 domain of MEKK2 (and/or MEKK3) ...
    cd06625
    Location:392 → 652
    STKc_MEKK3_like; Catalytic domain of Mitogen-Activated Protein (MAP)/Extracellular signal-Regulated Kinase (ERK) Kinase Kinase 3-like Serine/Threonine Kinases

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041769.1 Reference Mmul_10 Primary Assembly

    Range
    60072729..60147828
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015120053.2 → XP_014975539.1  mitogen-activated protein kinase kinase kinase 3 isoform X4

    UniProtKB/TrEMBL
    F7AIB6
    Conserved Domains (2) summary
    cd06405
    Location:45 → 123
    PB1_Mekk2_3; The PB1 domain is present in the two mitogen-activated protein kinase kinases MEKK2 and MEKK3 which are two members of the signaling kinase cascade involved in angiogenesis and early cardiovascular development. The PB1 domain of MEKK2 (and/or MEKK3) ...
    cd06625
    Location:357 → 617
    STKc_MEKK3_like; Catalytic domain of Mitogen-Activated Protein (MAP)/Extracellular signal-Regulated Kinase (ERK) Kinase Kinase 3-like Serine/Threonine Kinases

  2. XM_015120051.2 → XP_014975537.1  mitogen-activated protein kinase kinase kinase 3 isoform X1

    UniProtKB/TrEMBL
    F7AIB6, I0FRT5
    Conserved Domains (2) summary
    cd06405
    Location:76 → 154
    PB1_Mekk2_3; The PB1 domain is present in the two mitogen-activated protein kinase kinases MEKK2 and MEKK3 which are two members of the signaling kinase cascade involved in angiogenesis and early cardiovascular development. The PB1 domain of MEKK2 (and/or MEKK3) ...
    cd06625
    Location:388 → 648
    STKc_MEKK3_like; Catalytic domain of Mitogen-Activated Protein (MAP)/Extracellular signal-Regulated Kinase (ERK) Kinase Kinase 3-like Serine/Threonine Kinases

  3. XM_015120052.2 → XP_014975538.1  mitogen-activated protein kinase kinase kinase 3 isoform X3

    UniProtKB/TrEMBL
    F7AIB6, H9FUJ9
    Conserved Domains (2) summary
    cd06405
    Location:45 → 123
    PB1_Mekk2_3; The PB1 domain is present in the two mitogen-activated protein kinase kinases MEKK2 and MEKK3 which are two members of the signaling kinase cascade involved in angiogenesis and early cardiovascular development. The PB1 domain of MEKK2 (and/or MEKK3) ...
    cd06625
    Location:361 → 621
    STKc_MEKK3_like; Catalytic domain of Mitogen-Activated Protein (MAP)/Extracellular signal-Regulated Kinase (ERK) Kinase Kinase 3-like Serine/Threonine Kinases

  4. XM_028835760.1 → XP_028691593.1  mitogen-activated protein kinase kinase kinase 3 isoform X2

    UniProtKB/TrEMBL
    F7AIB6
    Related
    ENSMMUP00000022022.4, ENSMMUT00000023539.4
    Conserved Domains (2) summary
    cd06405
    Location:66 → 144
    PB1_Mekk2_3; The PB1 domain is present in the two mitogen-activated protein kinase kinases MEKK2 and MEKK3 which are two members of the signaling kinase cascade involved in angiogenesis and early cardiovascular development. The PB1 domain of MEKK2 (and/or MEKK3) ...
    cd06625
    Location:382 → 642
    STKc_MEKK3_like; Catalytic domain of Mitogen-Activated Protein (MAP)/Extracellular signal-Regulated Kinase (ERK) Kinase Kinase 3-like Serine/Threonine Kinases

  5. XM_015120054.2 → XP_014975540.2  mitogen-activated protein kinase kinase kinase 3 isoform X5

    UniProtKB/TrEMBL
    F7AIB6
    Conserved Domains (2) summary
    cd06405
    Location:21 → 99
    PB1_Mekk2_3; The PB1 domain is present in the two mitogen-activated protein kinase kinases MEKK2 and MEKK3 which are two members of the signaling kinase cascade involved in angiogenesis and early cardiovascular development. The PB1 domain of MEKK2 (and/or MEKK3) ...
    cd06625
    Location:337 → 597
    STKc_MEKK3_like; Catalytic domain of Mitogen-Activated Protein (MAP)/Extracellular signal-Regulated Kinase (ERK) Kinase Kinase 3-like Serine/Threonine Kinases
Nucleotide Protein
Heading Accession and Version

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