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Cyb561d1 cytochrome b-561 domain containing 1 [ Mus musculus (house mouse) ]

Gene ID: 72023, updated on 28-Oct-2024

Summary

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Official Symbol
Cyb561d1provided by MGI
Official Full Name
cytochrome b-561 domain containing 1provided by MGI
Primary source
MGI:MGI:1919273
See related
Ensembl:ENSMUSG00000048796 AllianceGenome:MGI:1919273
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1600010M23Rik
Summary
Predicted to enable heme binding activity and oxidoreductase activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Orthologous to human CYB561D1 (cytochrome b561 family member D1). [provided by Alliance of Genome Resources, Oct 2024]
Expression
Ubiquitous expression in thymus adult (RPKM 5.4), spleen adult (RPKM 4.7) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Cyb561d1 in Genome Data Viewer
Location:
3 F2.3; 3 46.86 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (108103082..108109542, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (108195771..108202226, complement)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 40122 Neighboring gene adhesion molecule with Ig like domain 1 Neighboring gene ataxin 7-like 2 Neighboring gene synaptophysin like 2 Neighboring gene SIVA1, apoptosis-inducing factor pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Insertion of a neomycin selection cassette in the Amigo1 locus alters gene expression in the olfactory epithelium leading to region-specific defects in olfactory receptor neuron development. Raja R, et al. Genesis, 2024 Apr. PMID 38590146
  2. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
  3. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables heme binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transmembrane ascorbate ferrireductase activity IEA
Inferred from Electronic Annotation
more info
  
enables transmembrane monodehydroascorbate reductase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
probable transmembrane reductase CYB561D1
Names
cytochrome b561 domain-containing protein 1
NP_001074789.2
NP_082337.1
XP_006502189.1
XP_006502190.1
XP_006502191.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081320.2 → NP_001074789.2  probable transmembrane reductase CYB561D1 isoform 1

    See identical proteins and their annotated locations for NP_001074789.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    BB853561, BC060107
    Consensus CDS
    CCDS38598.1
    UniProtKB/Swiss-Prot
    A2AE42, B2RPT5
    Related
    ENSMUSP00000102266.2, ENSMUST00000106655.2
    Conserved Domains (1) summary
    cd08761
    Location:32 → 212
    Cyt_b561_CYB561D2_like; Eukaryotic cytochrome b(561), including the CYB561D2 gene product

  2. NM_028061.1 → NP_082337.1  probable transmembrane reductase CYB561D1 isoform 2

    See identical proteins and their annotated locations for NP_082337.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR and coding region, compared to variant 1. These differences cause translation initiation from a downstream ATG and an isoform (2) with a shorter N-terminus, compared to isoform 1.
    Source sequence(s)
    AK164441, BC060107
    Consensus CDS
    CCDS38599.1
    UniProtKB/TrEMBL
    Q3TPE5, Q6PAS2
    Related
    ENSMUSP00000070361.7, ENSMUST00000065664.7
    Conserved Domains (1) summary
    cd08761
    Location:1 → 154
    Cyt_b561_CYB561D2_like; Eukaryotic cytochrome b(561), including the CYB561D2 gene product

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    108103082..108109542 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006502127.3 → XP_006502190.1  probable transmembrane reductase CYB561D1 isoform X2

    UniProtKB/TrEMBL
    Q6PAS2
    Conserved Domains (1) summary
    cd08761
    Location:6 → 155
    Cyt_b561_CYB561D2_like; Eukaryotic cytochrome b(561), including the CYB561D2 gene product

  2. XM_006502128.4 → XP_006502191.1  probable transmembrane reductase CYB561D1 isoform X3

    See identical proteins and their annotated locations for XP_006502191.1

    UniProtKB/TrEMBL
    Q3TPE5, Q6PAS2
    Related
    ENSMUST00000155099.2
    Conserved Domains (1) summary
    cd08761
    Location:1 → 154
    Cyt_b561_CYB561D2_like; Eukaryotic cytochrome b(561), including the CYB561D2 gene product

  3. XM_006502126.2 → XP_006502189.1  probable transmembrane reductase CYB561D1 isoform X1

    UniProtKB/TrEMBL
    Q6PAS2
    Conserved Domains (1) summary
    cd08761
    Location:2 → 164
    Cyt_b561_CYB561D2_like; Eukaryotic cytochrome b(561), including the CYB561D2 gene product
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A2AE42.1 GenPept UniProtKB/Swiss-Prot:A2AE42

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