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Tsnaxip1 translin-associated factor X (Tsnax) interacting protein 1 [ Mus musculus (house mouse) ]

Gene ID: 72236, updated on 28-Oct-2024

Summary

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Official Symbol
Tsnaxip1provided by MGI
Official Full Name
translin-associated factor X (Tsnax) interacting protein 1provided by MGI
Primary source
MGI:MGI:1919486
See related
Ensembl:ENSMUSG00000031893 AllianceGenome:MGI:1919486
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
TXI1; 1700016K08Rik
Summary
Predicted to be involved in cell differentiation and spermatogenesis. Located in cytoplasm. Is expressed in brain; gonad; lateral ventricle choroid plexus; and lung. Orthologous to human TSNAXIP1 (translin associated factor X interacting protein 1). [provided by Alliance of Genome Resources, Oct 2024]
Expression
Restricted expression toward testis adult (RPKM 54.7) See more
Orthologs
human all
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Genomic context

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See Tsnaxip1 in Genome Data Viewer
Location:
8 D3; 8 53.04 cM
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (106554343..106571310)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (105827711..105844678)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4933405L10 gene Neighboring gene STARR-positive B cell enhancer ABC_E6678 Neighboring gene enkurin domain containing 1 Neighboring gene glucose-fructose oxidoreductase domain containing 2 Neighboring gene STARR-positive B cell enhancer ABC_E8850 Neighboring gene RAN binding protein 10 Neighboring gene STARR-positive B cell enhancer ABC_E2272 Neighboring gene STARR-positive B cell enhancer ABC_E2875 Neighboring gene STARR-positive B cell enhancer ABC_E3799 Neighboring gene centromere protein T Neighboring gene STARR-seq mESC enhancer starr_22544 Neighboring gene THAP domain containing 11 Neighboring gene STARR-seq mESC enhancer starr_22545 Neighboring gene nuclear transport factor 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Testis-specific proteins, TSNAXIP1 and 1700010I14RIK, are important for sperm motility and male fertility in mice. Kaneda Y, et al. Andrology, 2023 Jul. PMID 36598146, Free PMC Article
  2. Identification and characterization of cDNAs encoding four novel proteins that interact with translin associated factor-X. Bray JD, et al. Genomics, 2002 Jun. PMID 12036294
  3. Urogenital and caudal dysgenesis in adrenocortical dysplasia (acd) mice is caused by a splicing mutation in a novel telomeric regulator. Keegan CE, et al. Hum Mol Genet, 2005 Jan 1. PMID 15537664
  4. Tissue expression patterns identify mouse cilia genes. McClintock TS, et al. Physiol Genomics, 2008 Jan 17. PMID 17971504
  5. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC118240

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
  
involved_in spermatogenesis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in perinuclear region of cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
translin-associated factor X-interacting protein 1
Names
trax-interacting protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_024445.4 → NP_077765.1  translin-associated factor X-interacting protein 1

    See identical proteins and their annotated locations for NP_077765.1

    Status: PROVISIONAL

    Source sequence(s)
    AC116569, AC152826
    Consensus CDS
    CCDS22614.1
    UniProtKB/Swiss-Prot
    Q99P25, Q9DA98
    UniProtKB/TrEMBL
    A0A1D5RMC0
    Related
    ENSMUSP00000034365.5, ENSMUST00000034365.5
    Conserved Domains (1) summary
    pfam15739
    Location:100 → 203
    TSNAXIP1_N; Translin-associated factor X-interacting N-terminus

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    106554343..106571310
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011248511.3 → XP_011246813.1  translin-associated factor X-interacting protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A1D5RMC0
    Conserved Domains (2) summary
    pfam15739
    Location:99 → 202
    TSNAXIP1_N; Translin-associated factor X-interacting N-terminus
    pfam15742
    Location:151 → 348
    DUF4686; Domain of unknown function (DUF4686)

  2. XM_011248512.3 → XP_011246814.1  translin-associated factor X-interacting protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A1D5RMC0
    Conserved Domains (2) summary
    pfam15739
    Location:94 → 197
    TSNAXIP1_N; Translin-associated factor X-interacting N-terminus
    pfam15742
    Location:146 → 343
    DUF4686; Domain of unknown function (DUF4686)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q99P25.2 GenPept UniProtKB/Swiss-Prot:Q99P25

Gene LinkOut

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