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Dnajc22 DnaJ heat shock protein family (Hsp40) member C22 [ Mus musculus (house mouse) ]

Gene ID: 72778, updated on 28-Oct-2024

Summary

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Official Symbol
Dnajc22provided by MGI
Official Full Name
DnaJ heat shock protein family (Hsp40) member C22provided by MGI
Primary source
MGI:MGI:1920028
See related
Ensembl:ENSMUSG00000038009 AllianceGenome:MGI:1920028
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2810451A06Rik
Summary
Predicted to be active in membrane. Is expressed in brain; gut; liver lobe; and metanephros. Orthologous to human DNAJC22 (DnaJ heat shock protein family (Hsp40) member C22). [provided by Alliance of Genome Resources, Oct 2024]
Expression
Biased expression in liver adult (RPKM 41.6), large intestine adult (RPKM 20.1) and 9 other tissues See more
Orthologs
human all
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Genomic context

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See Dnajc22 in Genome Data Viewer
Location:
15 F1; 15 55.87 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (98991102..99002618)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (99099134..99104709)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene trophinin associated protein Neighboring gene microRNA 6960 Neighboring gene complement component 1, q subcomponent-like 4 Neighboring gene spermatogenesis associated, serine-rich 2 Neighboring gene predicted gene, 57817 Neighboring gene predicted gene, 25183 Neighboring gene STARR-seq mESC enhancer starr_39699 Neighboring gene predicted gene, 46538 Neighboring gene potassium voltage-gated channel, subfamily H (eag-related), member 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Wurst is essential for airway clearance and respiratory-tube size control. Behr M, et al. Nat Cell Biol, 2007 Jul. PMID 17558392
  2. Identification of transcripts with enriched expression in the developing and adult pancreas. Hoffman BG, et al. Genome Biol, 2008. PMID 18554416, Free PMC Article
  3. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
  4. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
  5. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Component Evidence Code Pubs
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
dnaJ homolog subfamily C member 22
Names
DnaJ (Hsp40) homolog, subfamily B, member 3; heat shock protein, DNAJ-like 3
DnaJ (Hsp40) homolog, subfamily C, member 22

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001418805.1 → NP_001405734.1  dnaJ homolog subfamily C member 22

    Status: VALIDATED

    Source sequence(s)
    AC157610
    UniProtKB/Swiss-Prot
    Q8CHS2

  2. NM_001418806.1 → NP_001405735.1  dnaJ homolog subfamily C member 22

    Status: VALIDATED

    Source sequence(s)
    AC157610
    UniProtKB/Swiss-Prot
    Q8CHS2

  3. NM_176835.3 → NP_789805.1  dnaJ homolog subfamily C member 22

    See identical proteins and their annotated locations for NP_789805.1

    Status: VALIDATED

    Source sequence(s)
    AC157610
    Consensus CDS
    CCDS27815.1
    UniProtKB/Swiss-Prot
    Q8CHS2
    Related
    ENSMUSP00000055482.7, ENSMUST00000061295.7
    Conserved Domains (1) summary
    smart00271
    Location:278 → 335
    DnaJ; DnaJ molecular chaperone homology domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    98991102..99002618
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006521457.5 → XP_006521520.1  dnaJ homolog subfamily C member 22 isoform X1

    See identical proteins and their annotated locations for XP_006521520.1

    UniProtKB/Swiss-Prot
    Q8CHS2
    Conserved Domains (1) summary
    smart00271
    Location:278 → 335
    DnaJ; DnaJ molecular chaperone homology domain
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8CHS2.1 GenPept UniProtKB/Swiss-Prot:Q8CHS2

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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