LINC01433 long intergenic non-protein coding RNA 1433 [Homo sapiens (human)] - Gene

Summary

Official Symbol: LINC01433provided by HGNC
Official Full Name: long intergenic non-protein coding RNA 1433provided by HGNC
Primary source: HGNC:HGNC:50746
See related: Ensembl:ENSG00000230176 AllianceGenome:HGNC:50746
Gene type: ncRNA
RefSeq status: VALIDATED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression: Low expression observed in reference dataset See more
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Genomic context

Location:: 20p13

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2023_10	current	GRCh38.p14 (GCF_000001405.40)	20	NC_000020.11 (4193090..4195953)
RS_2023_10	current	T2T-CHM13v2.0 (GCF_009914755.1)	20	NC_060944.1 (4227394..4230257)
105.20220307	previous assembly	GRCh37.p13 (GCF_000001405.25)	20	NC_000020.10 (4173737..4176600)

Chromosome 20 - NC_000020.11 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: HPA RNA-seq normal tissues
Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
BioProject: PRJEB4337
Publication: PMID 24309898
Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

LINC01433 targets miR-506-3p to promote the biological progress of nasopharyngeal carcinoma cells.
Title: LINC01433 targets miR-506-3p to promote the biological progress of nasopharyngeal carcinoma cells.
Long non-coding RNA linc01433 promotes tumorigenesis and progression in esophageal squamous cell carcinoma by sponging miR-1301.
Title: Long non-coding RNA linc01433 promotes tumorigenesis and progression in esophageal squamous cell carcinoma by sponging miR-1301.
Based on the similar expression levels of LINC01433 between non-small cell lung cancer and non-tumoral tissues and lack of association between expression levels and clinical data, LINC01433 is not a possible contributor to lung cancer in Iranian patients.
Title: Expression Analysis of the Long Non-Coding RNA LINC01433 in Lung Cancer.
LINC01433 participated in hepatocellular carcinoma progression through modulating the miR-1301/STAT3 axis
Title: LINC01433 promotes hepatocellular carcinoma progression via modulating the miR-1301/STAT3 axis.
High LINC01433 expression is associated with Cell Proliferation, Migration, and the Epithelial-Mesenchymal Transition in Breast Cancer.
Title: LINC01433/miR-2116-3p/MYC Feedback Loop Promotes Cell Proliferation, Migration, and the Epithelial-Mesenchymal Transition in Breast Cancer.
Linc01433 overexpression in lung cancer cells increased proliferation, migration, and invasion abilities, as well as epithelial-to-mesenchymal transition. Linc01433 is a cancer-related lncRNA that may have an oncogene-like effect in non-small cell lung cancer.
Title: Long non-coding RNA linc01433 promotes migration and invasion in non-small cell lung cancer.

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Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See studies and variants in dbVar

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General gene information

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NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.