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Fam76b family with sequence similarity 76, member B [ Mus musculus (house mouse) ]

Gene ID: 72826, updated on 28-Oct-2024

Summary

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Official Symbol
Fam76bprovided by MGI
Official Full Name
family with sequence similarity 76, member Bprovided by MGI
Primary source
MGI:MGI:1920076
See related
Ensembl:ENSMUSG00000037808 AllianceGenome:MGI:1920076
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2810485I05Rik
Summary
Predicted to be active in nuclear speck. Is expressed in esophagus and heart ventricle. Orthologous to human FAM76B (family with sequence similarity 76 member B). [provided by Alliance of Genome Resources, Oct 2024]
Expression
Ubiquitous expression in CNS E14 (RPKM 10.9), whole brain E14.5 (RPKM 9.9) and 26 other tissues See more
Orthologs
human all
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Genomic context

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See Fam76b in Genome Data Viewer
Location:
9 A1; 9 3.51 cM
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (13738490..13766033)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (13827194..13854687)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 39291 Neighboring gene predicted gene, 53498 Neighboring gene myotubularin related protein 2 Neighboring gene STARR-seq mESC enhancer starr_23340 Neighboring gene CapStarr-seq enhancer MGSCv37_chr9:13631030-13631139 Neighboring gene STARR-positive B cell enhancer ABC_E3815 Neighboring gene STARR-positive B cell enhancer ABC_E363 Neighboring gene centrosomal protein 57 Neighboring gene peptidylprolyl isomerase B pseudogene Neighboring gene STARR-seq mESC enhancer starr_23341 Neighboring gene RIKEN cDNA 1700019J19 gene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. The ATG5 interactome links clathrin-mediated vesicular trafficking with the autophagosome assembly machinery. Baines K, et al. Autophagy Rep, 2022. PMID 35449600, Free PMC Article
  2. Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method. Piao Y, et al. Genome Res, 2001 Sep. PMID 11544199, Free PMC Article
  3. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249
  4. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
  5. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 
  • Gene trapped (1) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Component Evidence Code Pubs
is_active_in nuclear speck IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nuclear speck ISO
Inferred from Sequence Orthology
more info
  
located_in nuclear speck ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
protein FAM76B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001358259.2 → NP_001345188.1  protein FAM76B isoform 2

    Status: VALIDATED

    Source sequence(s)
    CT010488
    Conserved Domains (1) summary
    pfam16046
    Location:6 → 327
    FAM76; FAM76 protein

  2. NM_176836.5 → NP_789806.1  protein FAM76B isoform 1

    See identical proteins and their annotated locations for NP_789806.1

    Status: VALIDATED

    Source sequence(s)
    CT010488
    Consensus CDS
    CCDS22819.1
    UniProtKB/Swiss-Prot
    Q3UMA6, Q80XP8, Q80YR1, Q8CI69
    Related
    ENSMUSP00000062642.6, ENSMUST00000059579.12
    Conserved Domains (1) summary
    pfam16046
    Location:6 → 328
    FAM76; FAM76 protein

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    13738490..13766033
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036155320.1 → XP_036011213.1  protein FAM76B isoform X1

    Conserved Domains (1) summary
    pfam16046
    Location:6 → 313
    FAM76; FAM76 protein

  2. XM_030244637.1 → XP_030100497.1  protein FAM76B isoform X3

    Conserved Domains (1) summary
    pfam16046
    Location:16 → 222
    FAM76; FAM76 protein

  3. XM_011242612.4 → XP_011240914.1  protein FAM76B isoform X2

    See identical proteins and their annotated locations for XP_011240914.1

    Conserved Domains (1) summary
    pfam16046
    Location:6 → 310
    FAM76; FAM76 protein

RNA

  1. XR_004935577.1 RNA Sequence

  2. XR_004935578.1 RNA Sequence

  3. XR_001779022.2 RNA Sequence

    Related
    ENSMUST00000156680.2

  4. XR_003948022.1 RNA Sequence

  5. XR_004935576.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q80XP8.1 GenPept UniProtKB/Swiss-Prot:Q80XP8

Gene LinkOut

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