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PWWP4 PWWP domain containing 4 [ Homo sapiens (human) ]

Gene ID: 728317, updated on 5-Mar-2024

Summary

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Official Symbol
PWWP4provided by HGNC
Official Full Name
PWWP domain containing 4provided by HGNC
Primary source
HGNC:HGNC:55197
See related
Ensembl:ENSG00000278803 AllianceGenome:HGNC:55197
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Orthologs
all
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Genomic context

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Location:
Xq28
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (153266147..153279145)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (151533668..151546674)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (152531608..152544602)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene MAGE family member A1 Neighboring gene uncharacterized LOC105373373 Neighboring gene PNMA family member 6F Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 21059 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 21060 Neighboring gene microRNA 12129 Neighboring gene zinc finger protein 275

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Comparative genome sequence analysis of the Bpa/Str region in mouse and Man. Mallon AM, et al. Genome Res, 2000 Jun. PMID 10854409, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

General gene information

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Markers

Homology

General protein information

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Preferred Names
PWWP domain-containing DNA repair factor 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001395996.1 → NP_001382925.1  PWWP domain-containing DNA repair factor 4

    Status: VALIDATED

    Source sequence(s)
    AC236972
    Consensus CDS
    CCDS94692.1
    UniProtKB/Swiss-Prot
    A0A494C071
    Related
    ENSP00000498408.1, ENST00000458091.5
    Conserved Domains (4) summary
    cd06080
    Location:1754 → 1833
    MUM1_like; Mutated melanoma-associated antigen 1 (MUM-1) is a melanoma-associated antigen (MAA). MUM-1 belongs to the mutated or aberrantly expressed type of MAAs, along with antigens such as CDK4, beta-catenin, gp100-in4, p15, and N-acetylglucosaminyltransferase ...
    PHA03247
    Location:1110 → 1442
    PHA03247; large tegument protein UL36; Provisional
    PHA03307
    Location:153 → 457
    PHA03307; transcriptional regulator ICP4; Provisional
    PRK07003
    Location:622 → 904
    PRK07003; DNA polymerase III subunit gamma/tau

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

    Range
    153266147..153279145
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047442418.1 → XP_047298374.1  PWWP domain-containing DNA repair factor 4 isoform X1

    UniProtKB/Swiss-Prot
    A0A494C071

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060947.1 Alternate T2T-CHM13v2.0

    Range
    151533668..151546674
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054327684.1 → XP_054183659.1  PWWP domain-containing DNA repair factor 4 isoform X1

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A494C071.1 GenPept UniProtKB/Swiss-Prot:A0A494C071

Gene LinkOut

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Molecular Biology Databases
Research Materials