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zmynd8.S zinc finger, MYND-type containing 8 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 733267, updated on 18-Sep-2024

Summary

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Official Symbol
zmynd8.S
Official Full Name
zinc finger, MYND-type containing 8 S homeolog
Primary source
Xenbase:XB-GENE-6253445
Locus tag
XELAEV_180461521mg
See related
EnsemblRapid:ENSXLAG00005036618
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
zmynd8
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Genomic context

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See zmynd8.S in Genome Data Viewer
Location:
chromosome: 9_10S
Exon count:
27
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 9_10S NC_054388.1 (8490806..8551553, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 9_10S NC_030741.1 (8373947..8428724, complement)

Chromosome 9_10S - NC_054388.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 2 (facilitated glucose transporter), member 10 S homeolog Neighboring gene EYA transcriptional coactivator and phosphatase 2 S homeolog Neighboring gene nuclear receptor coactivator 3 S homeolog Neighboring gene sulfatase 2 S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Xenopus RCOR2 (REST corepressor 2) interacts with ZMYND8, which is involved in neural differentiation. Zeng W, et al. Biochem Biophys Res Commun, 2010 Apr 16. PMID 20331974
  2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. These data reveal a RCOR2/ZMYND8 complex which might be involved in the regulation of neural differentiation.
    Title: Xenopus RCOR2 (REST corepressor 2) interacts with ZMYND8, which is involved in neural differentiation.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables DNA-binding transcription factor binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables transcription corepressor activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables transcription corepressor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within nervous system development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within phosphorylation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
protein kinase C-binding protein 1
Names
zinc finger and MYND domain containing protein 8

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001177440.1 → NP_001170911.1  protein kinase C-binding protein 1

    See identical proteins and their annotated locations for NP_001170911.1

    Status: PROVISIONAL

    Source sequence(s)
    GU942747
    UniProtKB/TrEMBL
    A0A974BXG8, D5LMF5
    Related
    ENSXLAP00005109641.1, ENSXLAT00005111843.1
    Conserved Domains (6) summary
    cd05841
    Location:309 → 389
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05508
    Location:191 → 289
    Bromo_RACK7; Bromodomain, RACK7_like subfamily. RACK7 (also called human protein kinase C-binding protein) was identified as a potential tumor suppressor genes, it shares domain architecture with BS69/ZMYND11; both have been implicated in the regulation of cellular ...
    cd15538
    Location:130 → 170
    PHD_PRKCBP1; PHD finger found in protein kinase C-binding protein 1 (PRKCBP1)
    pfam01753
    Location:1074 → 1108
    zf-MYND; MYND finger
    pfam07798
    Location:979 → 1070
    DUF1640; Protein of unknown function (DUF1640)
    pfam12064
    Location:466 → 659
    DUF3544; Domain of unknown function (DUF3544)

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054388.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    8490806..8551553 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041577848.1 → XP_041433782.1  protein kinase C-binding protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8J1LW84, A0A974BXG8
    Conserved Domains (6) summary
    cd05841
    Location:331 → 411
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05508
    Location:213 → 311
    Bromo_RACK7; Bromodomain, RACK7_like subfamily. RACK7 (also called human protein kinase C-binding protein) was identified as a potential tumor suppressor genes, it shares domain architecture with BS69/ZMYND11; both have been implicated in the regulation of cellular ...
    COG5034
    Location:89 → 195
    TNG2; Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]
    cd15538
    Location:152 → 192
    PHD_PRKCBP1; PHD finger found in protein kinase C-binding protein 1 (PRKCBP1)
    pfam11725
    Location:493 → 777
    AvrE; Pathogenicity factor
    cd06503
    Location:1021 → 1090
    ATP-synt_Fo_b; F-type ATP synthase, membrane subunit b

  2. XM_041577854.1 → XP_041433788.1  protein kinase C-binding protein 1 isoform X7

    UniProtKB/TrEMBL
    A0A8J1LWA9, A0A974BXG8
    Conserved Domains (6) summary
    cd05841
    Location:309 → 389
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05508
    Location:191 → 289
    Bromo_RACK7; Bromodomain, RACK7_like subfamily. RACK7 (also called human protein kinase C-binding protein) was identified as a potential tumor suppressor genes, it shares domain architecture with BS69/ZMYND11; both have been implicated in the regulation of cellular ...
    COG5034
    Location:67 → 173
    TNG2; Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]
    cd15538
    Location:130 → 170
    PHD_PRKCBP1; PHD finger found in protein kinase C-binding protein 1 (PRKCBP1)
    pfam11725
    Location:471 → 755
    AvrE; Pathogenicity factor
    cd06503
    Location:999 → 1068
    ATP-synt_Fo_b; F-type ATP synthase, membrane subunit b

  3. XM_041577852.1 → XP_041433786.1  protein kinase C-binding protein 1 isoform X5

    UniProtKB/TrEMBL
    A0A8J1LXL9, A0A974BXG8
    Conserved Domains (6) summary
    cd05841
    Location:310 → 390
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05508
    Location:192 → 290
    Bromo_RACK7; Bromodomain, RACK7_like subfamily. RACK7 (also called human protein kinase C-binding protein) was identified as a potential tumor suppressor genes, it shares domain architecture with BS69/ZMYND11; both have been implicated in the regulation of cellular ...
    COG5034
    Location:68 → 174
    TNG2; Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]
    cd15538
    Location:131 → 171
    PHD_PRKCBP1; PHD finger found in protein kinase C-binding protein 1 (PRKCBP1)
    pfam11725
    Location:472 → 756
    AvrE; Pathogenicity factor
    cd06503
    Location:1000 → 1069
    ATP-synt_Fo_b; F-type ATP synthase, membrane subunit b

  4. XM_041577847.1 → XP_041433781.1  protein kinase C-binding protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8J1LW84, A0A974BXG8
    Conserved Domains (6) summary
    cd05841
    Location:331 → 411
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05508
    Location:213 → 311
    Bromo_RACK7; Bromodomain, RACK7_like subfamily. RACK7 (also called human protein kinase C-binding protein) was identified as a potential tumor suppressor genes, it shares domain architecture with BS69/ZMYND11; both have been implicated in the regulation of cellular ...
    COG5034
    Location:89 → 195
    TNG2; Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]
    cd15538
    Location:152 → 192
    PHD_PRKCBP1; PHD finger found in protein kinase C-binding protein 1 (PRKCBP1)
    pfam11725
    Location:493 → 777
    AvrE; Pathogenicity factor
    cd06503
    Location:1021 → 1090
    ATP-synt_Fo_b; F-type ATP synthase, membrane subunit b

  5. XM_041577849.1 → XP_041433783.1  protein kinase C-binding protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8J1LWA4, A0A974BXG8
    Conserved Domains (6) summary
    cd05841
    Location:330 → 410
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05508
    Location:212 → 310
    Bromo_RACK7; Bromodomain, RACK7_like subfamily. RACK7 (also called human protein kinase C-binding protein) was identified as a potential tumor suppressor genes, it shares domain architecture with BS69/ZMYND11; both have been implicated in the regulation of cellular ...
    COG5034
    Location:88 → 194
    TNG2; Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]
    cd15538
    Location:151 → 191
    PHD_PRKCBP1; PHD finger found in protein kinase C-binding protein 1 (PRKCBP1)
    pfam11725
    Location:492 → 776
    AvrE; Pathogenicity factor
    cd06503
    Location:1020 → 1089
    ATP-synt_Fo_b; F-type ATP synthase, membrane subunit b

  6. XM_041577859.1 → XP_041433793.1  protein kinase C-binding protein 1 isoform X12

    UniProtKB/TrEMBL
    A0A8J1LWB4, A0A974BXG8
    Related
    ENSXLAP00005109656.1, ENSXLAT00005111858.1
    Conserved Domains (4) summary
    cd05841
    Location:258 → 338
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05508
    Location:140 → 238
    Bromo_RACK7; Bromodomain, RACK7_like subfamily. RACK7 (also called human protein kinase C-binding protein) was identified as a potential tumor suppressor genes, it shares domain architecture with BS69/ZMYND11; both have been implicated in the regulation of cellular ...
    pfam11725
    Location:420 → 700
    AvrE; Pathogenicity factor
    cd06503
    Location:948 → 1017
    ATP-synt_Fo_b; F-type ATP synthase, membrane subunit b

  7. XM_041577850.1 → XP_041433784.1  protein kinase C-binding protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A8J1LWM7, A0A974BXG8
    Conserved Domains (5) summary
    cd05841
    Location:331 → 411
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05508
    Location:213 → 311
    Bromo_RACK7; Bromodomain, RACK7_like subfamily. RACK7 (also called human protein kinase C-binding protein) was identified as a potential tumor suppressor genes, it shares domain architecture with BS69/ZMYND11; both have been implicated in the regulation of cellular ...
    COG5034
    Location:89 → 195
    TNG2; Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]
    cd15538
    Location:152 → 192
    PHD_PRKCBP1; PHD finger found in protein kinase C-binding protein 1 (PRKCBP1)
    cd06503
    Location:1009 → 1078
    ATP-synt_Fo_b; F-type ATP synthase, membrane subunit b

  8. XM_041577855.1 → XP_041433789.1  protein kinase C-binding protein 1 isoform X8

    UniProtKB/TrEMBL
    A0A8J1LWN2, A0A974BXG8
    Related
    ENSXLAP00005109655.1, ENSXLAT00005111857.1
    Conserved Domains (6) summary
    cd05841
    Location:331 → 411
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05508
    Location:213 → 311
    Bromo_RACK7; Bromodomain, RACK7_like subfamily. RACK7 (also called human protein kinase C-binding protein) was identified as a potential tumor suppressor genes, it shares domain architecture with BS69/ZMYND11; both have been implicated in the regulation of cellular ...
    COG5034
    Location:89 → 195
    TNG2; Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]
    cd15538
    Location:152 → 192
    PHD_PRKCBP1; PHD finger found in protein kinase C-binding protein 1 (PRKCBP1)
    pfam11725
    Location:493 → 777
    AvrE; Pathogenicity factor
    cd06503
    Location:1021 → 1090
    ATP-synt_Fo_b; F-type ATP synthase, membrane subunit b

  9. XM_041577853.1 → XP_041433787.1  protein kinase C-binding protein 1 isoform X6

    UniProtKB/TrEMBL
    A0A8J1LW89, A0A974BXG8
    Conserved Domains (6) summary
    cd05841
    Location:309 → 389
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05508
    Location:191 → 289
    Bromo_RACK7; Bromodomain, RACK7_like subfamily. RACK7 (also called human protein kinase C-binding protein) was identified as a potential tumor suppressor genes, it shares domain architecture with BS69/ZMYND11; both have been implicated in the regulation of cellular ...
    COG5034
    Location:67 → 173
    TNG2; Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]
    cd15538
    Location:130 → 170
    PHD_PRKCBP1; PHD finger found in protein kinase C-binding protein 1 (PRKCBP1)
    pfam11725
    Location:471 → 755
    AvrE; Pathogenicity factor
    cd06503
    Location:999 → 1068
    ATP-synt_Fo_b; F-type ATP synthase, membrane subunit b

  10. XM_041577851.1 → XP_041433785.1  protein kinase C-binding protein 1 isoform X4

    UniProtKB/TrEMBL
    A0A8J1LYH3, A0A974BXG8
    Related
    ENSXLAP00005109654.1, ENSXLAT00005111856.1
    Conserved Domains (6) summary
    cd05841
    Location:310 → 390
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05508
    Location:192 → 290
    Bromo_RACK7; Bromodomain, RACK7_like subfamily. RACK7 (also called human protein kinase C-binding protein) was identified as a potential tumor suppressor genes, it shares domain architecture with BS69/ZMYND11; both have been implicated in the regulation of cellular ...
    COG5034
    Location:68 → 174
    TNG2; Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]
    cd15538
    Location:131 → 171
    PHD_PRKCBP1; PHD finger found in protein kinase C-binding protein 1 (PRKCBP1)
    pfam11725
    Location:472 → 756
    AvrE; Pathogenicity factor
    cd06503
    Location:1000 → 1069
    ATP-synt_Fo_b; F-type ATP synthase, membrane subunit b

  11. XM_041577857.1 → XP_041433791.1  protein kinase C-binding protein 1 isoform X10

    UniProtKB/TrEMBL
    A0A8J1LXM4, A0A974BXG8
    Conserved Domains (6) summary
    cd05841
    Location:289 → 369
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05508
    Location:171 → 269
    Bromo_RACK7; Bromodomain, RACK7_like subfamily. RACK7 (also called human protein kinase C-binding protein) was identified as a potential tumor suppressor genes, it shares domain architecture with BS69/ZMYND11; both have been implicated in the regulation of cellular ...
    COG5034
    Location:47 → 153
    TNG2; Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]
    cd15538
    Location:110 → 150
    PHD_PRKCBP1; PHD finger found in protein kinase C-binding protein 1 (PRKCBP1)
    pfam11725
    Location:451 → 735
    AvrE; Pathogenicity factor
    cd06503
    Location:979 → 1048
    ATP-synt_Fo_b; F-type ATP synthase, membrane subunit b

  12. XM_041577856.1 → XP_041433790.1  protein kinase C-binding protein 1 isoform X9

    UniProtKB/TrEMBL
    A0A8J1LYH9, A0A974BXG8
    Conserved Domains (6) summary
    cd05841
    Location:291 → 371
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05508
    Location:173 → 271
    Bromo_RACK7; Bromodomain, RACK7_like subfamily. RACK7 (also called human protein kinase C-binding protein) was identified as a potential tumor suppressor genes, it shares domain architecture with BS69/ZMYND11; both have been implicated in the regulation of cellular ...
    COG5034
    Location:49 → 155
    TNG2; Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]
    cd15538
    Location:112 → 152
    PHD_PRKCBP1; PHD finger found in protein kinase C-binding protein 1 (PRKCBP1)
    pfam11725
    Location:453 → 737
    AvrE; Pathogenicity factor
    cd06503
    Location:981 → 1050
    ATP-synt_Fo_b; F-type ATP synthase, membrane subunit b

  13. XM_041577858.1 → XP_041433792.1  protein kinase C-binding protein 1 isoform X11

    UniProtKB/TrEMBL
    A0A8J1LW93, A0A974BXG8
    Conserved Domains (6) summary
    cd05841
    Location:331 → 411
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05508
    Location:213 → 311
    Bromo_RACK7; Bromodomain, RACK7_like subfamily. RACK7 (also called human protein kinase C-binding protein) was identified as a potential tumor suppressor genes, it shares domain architecture with BS69/ZMYND11; both have been implicated in the regulation of cellular ...
    COG5034
    Location:89 → 195
    TNG2; Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]
    cd15538
    Location:152 → 192
    PHD_PRKCBP1; PHD finger found in protein kinase C-binding protein 1 (PRKCBP1)
    pfam11725
    Location:493 → 777
    AvrE; Pathogenicity factor
    cd06503
    Location:1021 → 1090
    ATP-synt_Fo_b; F-type ATP synthase, membrane subunit b
Nucleotide Protein Strain
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