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dlx2.S distal-less homeobox 2 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 734247, updated on 4-Nov-2024

Summary

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Official Symbol
dlx2.S
Official Full Name
distal-less homeobox 2 S homeolog
Primary source
Xenbase:XB-GENE-17342444
Locus tag
XELAEV_18047170mg
See related
EnsemblRapid:ENSXLAG00005026555 AllianceGenome:Xenbase:XB-GENE-17342444
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
tes1; Xdll4; tes-1; X-dll4
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to act upstream of or within cell differentiation and negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Orthologous to human DLX2 (distal-less homeobox 2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See dlx2.S in Genome Data Viewer
Location:
chromosome: 9_10S
Exon count:
3
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 9_10S NC_054388.1 (66786461..66789749, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 9_10S NC_030741.1 (60127440..60130729, complement)

Chromosome 9_10S - NC_054388.1Genomic Context describing neighboring genes Neighboring gene methionine aminopeptidase 1D, mitochondrial-like Neighboring gene uncharacterized LOC121398973 Neighboring gene homeobox protein DLX-1 Neighboring gene integrin subunit alpha 6 S homeolog Neighboring gene pyruvate dehydrogenase kinase 1 S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC80142

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cell differentiation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Homeobox protein DLL-4-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001095731.1 → NP_001089200.1  Homeobox protein DLL-4-like

    See identical proteins and their annotated locations for NP_001089200.1

    Status: PROVISIONAL

    Source sequence(s)
    BC077782
    UniProtKB/TrEMBL
    A0A974BUM6, Q6DD47
    Related
    ENSXLAP00005078894.1, ENSXLAT00005080484.1
    Conserved Domains (2) summary
    pfam00046
    Location:129 → 182
    Homeobox; Homeobox domain
    pfam12413
    Location:29 → 106
    DLL_N; Homeobox protein distal-less-like N terminal

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054388.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    66786461..66789749 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases
Research Materials