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KIR3DH killer cell immunoglobulin-like receptor, 3 domains, hybrid [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 735306, updated on 18-Aug-2023

Summary

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Gene symbol
KIR3DH
Gene description
killer cell immunoglobulin-like receptor, 3 domains, hybrid
See related
Ensembl:ENSMMUG00000009456
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Also known as
KIR; KIR3DL; KIR-3DL; KIR3DH4; KIR3DL8; KIR3DL08; KIR3DL14; KIR3DS04; Mamu-KIR
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Genomic context

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See KIR3DH in Genome Data Viewer
Location:
chromosome: 19
Exon count:
9
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 19 NC_041772.1 (58210018..58220863, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) Unplaced Scaffold NW_015034336.1 (741..6363, complement)

Chromosome 19 - NC_041772.1Genomic Context describing neighboring genes Neighboring gene ATP synthase subunit g, mitochondrial pseudogene Neighboring gene killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 Neighboring gene killer-cell Ig-like receptor KIR3DH5 Neighboring gene killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 21

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Activating KIR copy number variation is associated with granzyme B release by NK cells during primary simian immunodeficiency virus infection in rhesus monkeys. Hellmann I, et al. J Virol, 2012 Dec. PMID 23015705, Free PMC Article
  2. Association of activating KIR copy number variation of NK cells with containment of SIV replication in rhesus monkeys. Hellmann I, et al. PLoS Pathog, 2011 Dec. PMID 22194686, Free PMC Article
  3. Cloning of rhesus monkey killer-cell Ig-like receptors (KIRs) from early pregnancy decidua. Grendell RL, et al. Tissue Antigens, 2001 Nov. PMID 11844144
  4. Multiple KIR gene polymorphisms are associated with plasma viral loads in SIV-infected rhesus macaques. Chaichompoo P, et al. Cell Immunol, 2010. PMID 20430371, Free PMC Article
  5. A splice site mutation converts an inhibitory killer cell Ig-like receptor into an activating one. Blokhuis JH, et al. Mol Immunol, 2009 Feb. PMID 19019442

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. NK cells expressing high levels of activating KIRs efficiently kill SIVmac251-infected cells, and this efficient killing contributes to the NK cell-mediated control of replication of this virus during early infection.
    Title: Activating KIR copy number variation is associated with granzyme B release by NK cells during primary simian immunodeficiency virus infection in rhesus monkeys.
  2. An association between copy numbers of KIR3DH genes and control of SIV replication in Mamu-A*01 rhesus monkeys that express restrictive TRIM5 alleles.
    Title: Association of activating KIR copy number variation of NK cells with containment of SIV replication in rhesus monkeys.
Submit: New GeneRIF Correction

General gene information

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Homology

General protein information

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Preferred Names
killer cell immunoglobulin-like receptor, 3 domains, hybrid
Names
KIR-2DL/3DL phusion
KIR-2DL/3DL protein
KIR-3DL phusion
KIR-3DL08 protein
KIR3DL02/3DL08A
KIR3DL02/3DL08A protein
Killer-cell immunoglobulin-like receptor
Mamu-KIR3DL08
Mamu-KIR3DS04
killer cell immunoglobulin-like receptor KIR3DH6
killer cell immunoglobulin-like receptor KIR3DM5
killer immunoglobulin-like receptor 3DS
killer immunoglobulin-like receptor KIR3DL
killer immunoglobulin-like receptor KIR3DL-like 2
killer immunoglobulin-like receptor KIR3DL8
killer immunoglobulin-like receptor KIRDL8
killer-cell Ig-like receptor KIR3DL16
killer-cell Ig-like receptor KIR3DL17

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001318346.1 → NP_001305275.1  killer cell immunoglobulin-like receptor, 3 domains, hybrid precursor

    Status: PROVISIONAL

    Source sequence(s)
    GU112330
    UniProtKB/TrEMBL
    A0A3F2XHD2
    Related
    ENSMMUP00000070387.1, ENSMMUT00000086646.1
    Conserved Domains (2) summary
    smart00410
    Location:34 → 104
    IG_like; Immunoglobulin like
    cl11960
    Location:126 → 220
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041772.1 Reference Mmul_10 Primary Assembly

    Range
    58210018..58220863 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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