U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Ttc27 tetratricopeptide repeat domain 27 [ Mus musculus (house mouse) ]

Gene ID: 74196, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
Ttc27provided by MGI
Official Full Name
tetratricopeptide repeat domain 27provided by MGI
Primary source
MGI:MGI:1921446
See related
Ensembl:ENSMUSG00000024078 AllianceGenome:MGI:1921446
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2610511O17Rik
Summary
Orthologous to human TTC27 (tetratricopeptide repeat domain 27). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 5.9), liver E14 (RPKM 4.6) and 26 other tissues See more
Orthologs
human all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Ttc27 in Genome Data Viewer
Location:
17 E2; 17 45.64 cM
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (75024730..75170565)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (74717735..74863570)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_43225 Neighboring gene predicted gene, 31645 Neighboring gene baculoviral IAP repeat-containing 6 Neighboring gene STARR-seq mESC enhancer starr_43226 Neighboring gene STARR-positive B cell enhancer ABC_E9965 Neighboring gene STARR-positive B cell enhancer ABC_E3215 Neighboring gene STARR-positive B cell enhancer ABC_E7557 Neighboring gene STARR-seq mESC enhancer starr_43230 Neighboring gene STARR-seq mESC enhancer starr_43231 Neighboring gene predicted gene, 31759 Neighboring gene predicted gene, 31818

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Functional genomic landscape of cancer-intrinsic evasion of killing by T cells. Lawson KA, et al. Nature, 2020 Oct. PMID 32968282, Free PMC Article
  2. Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways. Sang L, et al. Cell, 2011 May 13. PMID 21565611, Free PMC Article
  3. Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators. St-Denis N, et al. Cell Rep, 2016 Nov 22. PMID 27880917
  4. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
  5. Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function. Zhang T, et al. Sci Rep, 2017 Apr 5. PMID 28378742, Free PMC Article

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (4) 

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

Go to the top of the page Help
Preferred Names
tetratricopeptide repeat protein 27
Names
TPR repeat protein 27

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_152817.4 → NP_690030.3  tetratricopeptide repeat protein 27

    See identical proteins and their annotated locations for NP_690030.3

    Status: VALIDATED

    Source sequence(s)
    AI118251, AK030942, AK049324
    Consensus CDS
    CCDS28972.1
    UniProtKB/Swiss-Prot
    Q3THU0, Q8C7S8, Q8CD92, Q8K1D9
    Related
    ENSMUSP00000024882.7, ENSMUST00000024882.8
    Conserved Domains (2) summary
    sd00006
    Location:531 → 559
    TPR; TPR repeat [structural motif]
    pfam13414
    Location:567 → 629
    TPR_11; TPR repeat

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    75024730..75170565
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006525025.5 → XP_006525088.1  tetratricopeptide repeat protein 27 isoform X1

    UniProtKB/Swiss-Prot
    Q8CD92
    Related
    ENSMUSP00000157097.2, ENSMUST00000234568.2
    Conserved Domains (2) summary
    COG0457
    Location:481 → 635
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    sd00006
    Location:531 → 559
    TPR; TPR repeat [structural motif]

  2. XM_006525027.5 → XP_006525090.1  tetratricopeptide repeat protein 27 isoform X2

    Conserved Domains (3) summary
    TIGR02521
    Location:152 → 295
    type_IV_pilW; type IV pilus biogenesis/stability protein PilW
    TIGR02917
    Location:39 → 259
    PEP_TPR_lipo; putative PEP-CTERM system TPR-repeat lipoprotein
    sd00006
    Location:158 → 186
    TPR; TPR repeat [structural motif]

RNA

  1. XR_003952200.1 RNA Sequence

  2. XR_003952201.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8CD92.2 GenPept UniProtKB/Swiss-Prot:Q8CD92

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools