U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

VDR vitamin D receptor [ Homo sapiens (human) ]

Gene ID: 7421, updated on 5-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
VDRprovided by HGNC
Official Full Name
vitamin D receptorprovided by HGNC
Primary source
HGNC:HGNC:12679
See related
Ensembl:ENSG00000111424 MIM:601769; AllianceGenome:HGNC:12679
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
NR1I1; PPP1R163
Summary
This gene encodes vitamin D3 receptor, which is a member of the nuclear hormone receptor superfamily of ligand-inducible transcription factors. This receptor also functions as a receptor for the secondary bile acid, lithocholic acid. Downstream targets of vitamin D3 receptor are principally involved in mineral metabolism, though this receptor regulates a variety of other metabolic pathways, such as those involved in immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Jun 2018]
Expression
Broad expression in small intestine (RPKM 24.6), duodenum (RPKM 24.1) and 14 other tissues See more
Orthologs
mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See VDR in Genome Data Viewer
Location:
12q13.11
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 12 NC_000012.12 (47841537..47904994, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 12 NC_060936.1 (47802918..47866398, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (48235320..48298777, complement)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124902926 Neighboring gene histone deacetylase 7 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6264 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4400 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6265 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6266 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6267 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:48211237-48211897 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:48212615-48213188 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4402 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4403 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:48214527-48215448 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6268 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6269 Neighboring gene long intergenic non-protein coding RNA 2354 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:48236992-48237565 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:48237566-48238138 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:48239663-48240164 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:48262276-48262776 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6271 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6272 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:48276324-48276836 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6273 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6274 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6275 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6276 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4404 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:48329073-48329573 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr12:48353651-48354181 Neighboring gene ReSE screen-validated silencer GRCh37_chr12:48367908-48368120 Neighboring gene transmembrane protein 106C Neighboring gene uncharacterized LOC105369752 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:48375074-48375619 Neighboring gene collagen type II alpha 1 chain

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Vitamin D receptor polymorphisms and survival in patients with cutaneous melanoma: a population-based study. Orlow I, et al. Carcinogenesis, 2016 Jan. PMID 26521212, Free PMC Article
  2. Association Between Vitamin D Receptor Polymorphism and Familial Mediterranean Fever Disease in Turkish Children. Kizildag S, et al. Biochem Genet, 2016 Apr. PMID 26742922
  3. Vitamin D receptor GATG haplotype association with atherosclerotic disease in patients with rheumatoid arthritis. López-Mejías R, et al. Atherosclerosis, 2016 Feb. PMID 26724524
  4. Alterations in vitamin D signaling pathway in gastric cancer progression: a study of vitamin D receptor expression in human normal, premalignant, and malignant gastric tissue. Wen Y, et al. Int J Clin Exp Pathol, 2015. PMID 26722516, Free PMC Article
  5. Impact of the polymorphism in vitamin D receptor gene BsmI and the risk of systemic lupus erythematosus: an updated meta-analysis. Hu W, et al. Clin Rheumatol, 2016 Apr. PMID 26712498

See all (1000) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Association of Vitamin D receptor gene polymorphism with susceptibility and prognosis of Systemic Lupus Erythematosus in Chinese patients.
    Title: Association of Vitamin D receptor gene polymorphism with susceptibility and prognosis of Systemic Lupus Erythematosus in Chinese patients.
  2. Assessment of the contribution of VDR and VDBP/GC genes in the pathogenesis of celiac disease.
    Title: Assessment of the contribution of VDR and VDBP/GC genes in the pathogenesis of celiac disease.
  3. Prevalence and effects of Vitamin D receptor polymorphism on bone mineral density and metabolism in patients with systemic sclerosis: a preliminary study.
    Title: Prevalence and effects of Vitamin D receptor polymorphism on bone mineral density and metabolism in patients with systemic sclerosis: a preliminary study.
  4. Association of single nucleotide genetic polymorphisms of vitamin D receptor and calcium-sensitive receptor with calcium-containing kidney stones in Chinese Dai populations: a prospective multi-center study.
    Title: Association of single nucleotide genetic polymorphisms of vitamin D receptor and calcium-sensitive receptor with calcium-containing kidney stones in Chinese Dai populations: a prospective multi-center study.
  5. Molecular investigation of vitamin D receptor (VDR) genetic variants and their impact on VDR mRNA and serum vitamin D levels in allergic rhinitis in an Indian population: A case-control study.
    Title: Molecular investigation of vitamin D receptor (VDR) genetic variants and their impact on VDR mRNA and serum vitamin D levels in allergic rhinitis in an Indian population: A case-control study.
  6. Association of vitamin D receptor gene polymorphisms with caries risk in children: a systematic review and meta-analysis.
    Title: Association of vitamin D receptor gene polymorphisms with caries risk in children: a systematic review and meta-analysis.
  7. Role of Vitamin D Receptor (BsmI-VDR) and Insulin Receptor (NsiI-A/G) Gene Polymorphisms in Colorectal Adenoma Susceptibility.
    Title: Role of Vitamin D Receptor (BsmI-VDR) and Insulin Receptor (NsiI-A/G) Gene Polymorphisms in Colorectal Adenoma Susceptibility.
  8. The Impact of Vitamin D Receptor Gene Polymorphisms (FokI, ApaI, TaqI) in Correlation with Oxidative Stress and Hormonal and Dermatologic Manifestations in Polycystic Ovary Syndrome.
    Title: The Impact of Vitamin D Receptor Gene Polymorphisms (FokI, ApaI, TaqI) in Correlation with Oxidative Stress and Hormonal and Dermatologic Manifestations in Polycystic Ovary Syndrome.
  9. Vitamin D Status, Vitamin D Receptor Polymorphisms, and Risk of Type 2 Diabetes: A Prospective Cohort Study.
    Title: Vitamin D Status, Vitamin D Receptor Polymorphisms, and Risk of Type 2 Diabetes: A Prospective Cohort Study.
  10. Vitamin D receptor gene polymorphisms and multiple myeloma: a meta-analysis.
    Title: Vitamin D receptor gene polymorphisms and multiple myeloma: a meta-analysis.
Submit: New GeneRIF Correction See all GeneRIFs (1950)

Phenotypes

Go to the top of the page Help

Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Associated conditions

Description Tests
Vitamin D-dependent rickets type II with alopecia
MedGen: C0342646 OMIM: 277440 GeneReviews: Not available
Compare labs

EBI GWAS Catalog

Description
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.
EBI GWAS Catalog
Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.
EBI GWAS Catalog

Variation

Go to the top of the page Help

See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

HIV-1 interactions

Go to the top of the page Help

Replication interactions

Interaction Pubs
Knockdown of vitamin D (1,25- dihydroxyvitamin D3) receptor (VDR) by siRNA inhibits HIV-1 replication in HeLa P4/R5 cells PubMed

Protein interactions

Protein Gene Interaction Pubs
Envelope surface glycoprotein gp120 env HIV-1 gp160 and gp120 contain alpha-N-acetylgalactosaminidase (Nagalase) activity, which deglycosylates serum vitamin D3-binding protein (Gc protein) PubMed

Go to the HIV-1, Human Interaction Database

Pathways from PubChem

Go to the top of the page

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
contributes_to DNA-binding transcription factor activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables DNA-binding transcription factor activity, RNA polymerase II-specific ISA
Inferred from Sequence Alignment
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables bile acid nuclear receptor activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables calcitriol binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables calcitriol binding IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables lithocholic acid binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables nuclear receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables nuclear receptor activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables nuclear receptor activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables nuclear retinoid X receptor binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables nuclear retinoid X receptor binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
contributes_to vitamin D response element binding IBA
Inferred from Biological aspect of Ancestor
more info
  
contributes_to vitamin D response element binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in apoptotic process involved in mammary gland involution IEA
Inferred from Electronic Annotation
more info
  
involved_in calcium ion transport IEA
Inferred from Electronic Annotation
more info
  
involved_in cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cell morphogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in decidualization IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in intestinal absorption IEA
Inferred from Electronic Annotation
more info
  
involved_in intracellular calcium ion homeostasis IEA
Inferred from Electronic Annotation
more info
  
involved_in lactation IEA
Inferred from Electronic Annotation
more info
  
involved_in mRNA transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in mRNA transcription by RNA polymerase II ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in mammary gland branching involved in pregnancy IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within negative regulation of DNA-templated transcription IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in negative regulation of cell population proliferation IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in negative regulation of keratinocyte proliferation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in negative regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in negative regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in nuclear receptor-mediated bile acid signaling pathway IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in phosphate ion transmembrane transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in positive regulation of apoptotic process involved in mammary gland involution IEA
Inferred from Electronic Annotation
more info
  
involved_in positive regulation of bone mineralization NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in positive regulation of gene expression IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of keratinocyte differentiation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in positive regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in positive regulation of vitamin D 24-hydroxylase activity IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in positive regulation of vitamin D receptor signaling pathway IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in positive regulation of vitamin D receptor signaling pathway ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in regulation of calcidiol 1-monooxygenase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in response to bile acid IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in retinoic acid receptor signaling pathway IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in skeletal system development IEA
Inferred from Electronic Annotation
more info
  
involved_in vitamin D receptor signaling pathway IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in vitamin D receptor signaling pathway IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of RNA polymerase II transcription regulator complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of RNA polymerase II transcription regulator complex IPI
Inferred from Physical Interaction
more info
 PubMed 
part_of RNA polymerase II transcription regulator complex ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in chromatin IDA
Inferred from Direct Assay
more info
 PubMed 
located_in chromatin ISA
Inferred from Sequence Alignment
more info
  
located_in cytosol IDA
Inferred from Direct Assay
more info
  
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
  
located_in nucleoplasm TAS
Traceable Author Statement
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
part_of receptor complex IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
vitamin D3 receptor
Names
1,25-dihydroxyvitamin D3 receptor
nuclear receptor subfamily 1 group I member 1
protein phosphatase 1, regulatory subunit 163
vitamin D (1,25- dihydroxyvitamin D3) receptor

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_008731.1 RefSeqGene

    Range
    5038..68495
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_000376.3 → NP_000367.1  vitamin D3 receptor isoform VDRA

    See identical proteins and their annotated locations for NP_000367.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) represents the predominant transcript and encodes two isoforms, which result from the use of alternative in-frame translation termination codons. The shorter isoform (VDRA, also known as VDR) results from translation termination at the upstream UGA stop codon, while the longer isoform (VDRAx, also known as VDRx) results from UGA stop codon readthrough to the downstream UGA termination codon. This RefSeq represents the shorter isoform (VDRA). Variants 1 and 2 encode the same isoform.
    Source sequence(s)
    AC004466, BC060832, BM908433, BQ002808, CF138099, J03258
    Consensus CDS
    CCDS8757.1
    UniProtKB/Swiss-Prot
    B2R5Q1, G3V1V9, P11473, Q5PSV3
    UniProtKB/TrEMBL
    B6ZGT0, F1D8P8
    Related
    ENSP00000449573.2, ENST00000549336.6
    Conserved Domains (2) summary
    cd06933
    Location:124 → 426
    NR_LBD_VDR; The ligand binding domain of vitamin D receptors, a member of the nuclear receptor superfamily
    cd06955
    Location:16 → 122
    NR_DBD_VDR; DNA-binding domain of vitamin D receptors (VDR) is composed of two C4-type zinc fingers

  2. NM_001017535.2 → NP_001017535.1  vitamin D3 receptor isoform VDRA

    See identical proteins and their annotated locations for NP_001017535.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) contains an additional 5' non-coding exon compared to variant 1. Variants 1 and 2 encode the same isoform (VDRA).
    Source sequence(s)
    AC004466, AC121338
    Consensus CDS
    CCDS8757.1
    UniProtKB/Swiss-Prot
    B2R5Q1, G3V1V9, P11473, Q5PSV3
    UniProtKB/TrEMBL
    B6ZGT0, F1D8P8
    Conserved Domains (2) summary
    cd06933
    Location:124 → 426
    NR_LBD_VDR; The ligand binding domain of vitamin D receptors, a member of the nuclear receptor superfamily
    cd06955
    Location:16 → 122
    NR_DBD_VDR; DNA-binding domain of vitamin D receptors (VDR) is composed of two C4-type zinc fingers

  3. NM_001017536.2 → NP_001017536.1  vitamin D3 receptor isoform VDRB1

    See identical proteins and their annotated locations for NP_001017536.1

    Status: REVIEWED

    Source sequence(s)
    AC004466, BC060832, BM685276
    Consensus CDS
    CCDS55820.1
    UniProtKB/TrEMBL
    B6ZGT0
    Related
    ENSP00000447173.1, ENST00000550325.5
    Conserved Domains (2) summary
    cd06933
    Location:174 → 476
    NR_LBD_VDR; The ligand binding domain of vitamin D receptors, a member of the nuclear receptor superfamily
    cd06955
    Location:66 → 172
    NR_DBD_VDR; DNA-binding domain of vitamin D receptors (VDR) is composed of two C4-type zinc fingers

  4. NM_001364085.2 → NP_001351014.1  vitamin D3 receptor isoform VDRAx

    Status: REVIEWED

    Source sequence(s)
    AC004466, AC121338
    Consensus CDS
    CCDS91689.1
    UniProtKB/TrEMBL
    A0A5K1VW50, B6ZGT0
    Related
    ENSP00000229022.5, ENST00000229022.9
    Conserved Domains (2) summary
    cd06933
    Location:124 → 426
    NR_LBD_VDR; The ligand binding domain of vitamin D receptors, a member of the nuclear receptor superfamily
    cd06955
    Location:16 → 122
    NR_DBD_VDR; DNA-binding domain of vitamin D receptors (VDR) is composed of two C4-type zinc fingers

  5. NM_001374661.1 → NP_001361590.1  vitamin D3 receptor isoform VDRA

    Status: REVIEWED

    Source sequence(s)
    AC004466, AC121338
    Consensus CDS
    CCDS8757.1
    UniProtKB/Swiss-Prot
    B2R5Q1, G3V1V9, P11473, Q5PSV3
    UniProtKB/TrEMBL
    B6ZGT0, F1D8P8
    Conserved Domains (2) summary
    cd06933
    Location:124 → 426
    NR_LBD_VDR; The ligand binding domain of vitamin D receptors, a member of the nuclear receptor superfamily
    cd06955
    Location:16 → 122
    NR_DBD_VDR; DNA-binding domain of vitamin D receptors (VDR) is composed of two C4-type zinc fingers

  6. NM_001374662.1 → NP_001361591.1  vitamin D3 receptor isoform VDRA

    Status: REVIEWED

    Source sequence(s)
    AC004466, AC121338
    Consensus CDS
    CCDS8757.1
    UniProtKB/Swiss-Prot
    B2R5Q1, G3V1V9, P11473, Q5PSV3
    UniProtKB/TrEMBL
    B6ZGT0, F1D8P8
    Conserved Domains (2) summary
    cd06933
    Location:124 → 426
    NR_LBD_VDR; The ligand binding domain of vitamin D receptors, a member of the nuclear receptor superfamily
    cd06955
    Location:16 → 122
    NR_DBD_VDR; DNA-binding domain of vitamin D receptors (VDR) is composed of two C4-type zinc fingers

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p14 Primary Assembly

    Range
    47841537..47904994 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047429500.1 → XP_047285456.1  vitamin D3 receptor isoform X2

    UniProtKB/Swiss-Prot
    B2R5Q1, G3V1V9, P11473, Q5PSV3
    UniProtKB/TrEMBL
    F1D8P8

  2. XM_024449178.2 → XP_024304946.1  vitamin D3 receptor isoform X1

    UniProtKB/TrEMBL
    B6ZGT0
    Conserved Domains (2) summary
    cd06933
    Location:147 → 449
    NR_LBD_VDR; The ligand binding domain of vitamin D receptors, a member of the nuclear receptor superfamily
    cd06955
    Location:39 → 145
    NR_DBD_VDR; DNA-binding domain of vitamin D receptors (VDR) is composed of two C4-type zinc fingers

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060936.1 Alternate T2T-CHM13v2.0

    Range
    47802918..47866398 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054373132.1 → XP_054229107.1  vitamin D3 receptor isoform X2

    UniProtKB/Swiss-Prot
    B2R5Q1, G3V1V9, P11473, Q5PSV3
    UniProtKB/TrEMBL
    F1D8P8

  2. XM_054373131.1 → XP_054229106.1  vitamin D3 receptor isoform X1

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P11473.1 GenPept UniProtKB/Swiss-Prot:P11473

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Medical
Molecular Biology Databases
Research Materials
Tools
Miscellaneous