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Magea14 MAGE family member A14 [ Mus musculus (house mouse) ]

Gene ID: 74279, updated on 2-Nov-2024

Summary

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Official Symbol
Magea14provided by MGI
Official Full Name
MAGE family member A14provided by MGI
Primary source
MGI:MGI:1921529
See related
Ensembl:ENSMUSG00000031118 AllianceGenome:MGI:1921529
Gene type
protein coding
RefSeq status
PREDICTED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1700080O16Rik
Summary
Predicted to enable histone deacetylase binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus. Orthologous to several human genes including MAGEA10 (MAGE family member A10). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Restricted expression toward testis adult (RPKM 17.8) See more
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Genomic context

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See Magea14 in Genome Data Viewer
Location:
X A5; X 28.33 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (51057570..51062379, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (51968693..51973502, complement)

Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene predicted gene, 35727 Neighboring gene STARR-seq mESC enhancer starr_47165 Neighboring gene ubiquitin specific peptidase 26 Neighboring gene STARR-seq mESC enhancer starr_47166 Neighboring gene predicted gene, 22539 Neighboring gene STARR-seq mESC enhancer starr_47167 Neighboring gene predicted gene, 35790 Neighboring gene STARR-seq mESC enhancer starr_47168 Neighboring gene STARR-seq mESC enhancer starr_47170 Neighboring gene glypican 4 Neighboring gene STARR-seq mESC enhancer starr_47171 Neighboring gene STARR-seq mESC enhancer starr_47173 Neighboring gene STARR-seq mESC enhancer starr_47175 Neighboring gene STARR-seq mESC enhancer starr_47176 Neighboring gene STARR-seq mESC enhancer starr_47177 Neighboring gene glypican 3 Neighboring gene microRNA 6384

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Regulatory variation at glypican-3 underlies a major growth QTL in mice. Oliver F, et al. PLoS Biol, 2005 May. PMID 15799711, Free PMC Article
  2. A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome. Mural RJ, et al. Science, 2002 May 31. PMID 12040188
  3. USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities. Liu C, et al. Sci Adv, 2023 May 19. PMID 37196079, Free PMC Article
  4. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC130196, MGC130197

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables histone deacetylase binding ISO
Inferred from Sequence Orthology
more info
  
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in negative regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
uncharacterized protein LOC74279

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_028851.1 → NP_083127.1  uncharacterized protein LOC74279

    See identical proteins and their annotated locations for NP_083127.1

    Status: PREDICTED

    Source sequence(s)
    AK006959
    Consensus CDS
    CCDS53068.1
    UniProtKB/TrEMBL
    Q9D9G4
    Related
    ENSMUSP00000033449.2, ENSMUST00000033449.8
    Conserved Domains (2) summary
    pfam01454
    Location:100 → 252
    MAGE; MAGE family
    pfam12440
    Location:16 → 66
    MAGE_N; Melanoma associated antigen family N terminal

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000086.8 Reference GRCm39 C57BL/6J

    Range
    51057570..51062379 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006541552.4 → XP_006541615.1  uncharacterized protein LOC74279 isoform X1

    See identical proteins and their annotated locations for XP_006541615.1

    UniProtKB/TrEMBL
    Q9D9G4
    Related
    ENSMUSP00000110516.2, ENSMUST00000114866.2
    Conserved Domains (2) summary
    pfam01454
    Location:100 → 252
    MAGE; MAGE family
    pfam12440
    Location:16 → 66
    MAGE_N; Melanoma associated antigen family N terminal

  2. XM_030251513.1 → XP_030107373.1  uncharacterized protein LOC74279 isoform X1

    UniProtKB/TrEMBL
    Q9D9G4
    Conserved Domains (2) summary
    pfam01454
    Location:100 → 252
    MAGE; MAGE family
    pfam12440
    Location:16 → 66
    MAGE_N; Melanoma associated antigen family N terminal

  3. XM_006541551.4 → XP_006541614.1  uncharacterized protein LOC74279 isoform X1

    See identical proteins and their annotated locations for XP_006541614.1

    UniProtKB/TrEMBL
    Q9D9G4
    Conserved Domains (2) summary
    pfam01454
    Location:100 → 252
    MAGE; MAGE family
    pfam12440
    Location:16 → 66
    MAGE_N; Melanoma associated antigen family N terminal
Nucleotide Protein Strain
Heading Accession and Version

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