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Apol7a apolipoprotein L 7a [ Mus musculus (house mouse) ]

Gene ID: 75761, updated on 2-Nov-2024

Summary

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Official Symbol
Apol7aprovided by MGI
Official Full Name
apolipoprotein L 7aprovided by MGI
Primary source
MGI:MGI:1923011
See related
Ensembl:ENSMUSG00000010601 AllianceGenome:MGI:1923011
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Apol3; 9130022K13Rik
Summary
Predicted to enable lipid binding activity. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human APOL2 (apolipoprotein L2). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in liver adult (RPKM 21.3), large intestine adult (RPKM 17.0) and 6 other tissues See more
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Genomic context

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See Apol7a in Genome Data Viewer
Location:
15 D3; 15 36.4 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (77272417..77283310, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (77388217..77399110, complement)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene predicted gene 3787 Neighboring gene predicted gene, 53900 Neighboring gene predicted gene, 41353 Neighboring gene apolipoprotein L 9a Neighboring gene predicted gene, 36194 Neighboring gene apolipoprotein L 7b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Mouse screen reveals multiple new genes underlying mouse and human hearing loss. Ingham NJ, et al. PLoS Biol, 2019 Apr. PMID 30973865, Free PMC Article
  2. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
  3. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables lipid binding IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
apolipoprotein L 7a
Names
apolipoprotein L 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001164640.1 → NP_001158112.1  apolipoprotein L 7a

    See identical proteins and their annotated locations for NP_001158112.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AK018646, AK085956, AL772386, BC139138
    Consensus CDS
    CCDS37125.1
    UniProtKB/TrEMBL
    B2RT54, E9Q635, Q9D2Y0
    Related
    ENSMUSP00000135864.2, ENSMUST00000175919.8
    Conserved Domains (1) summary
    pfam05461
    Location:22 → 416
    ApoL; Apolipoprotein L

  2. NM_029419.2 → NP_083695.2  apolipoprotein L 7a

    See identical proteins and their annotated locations for NP_083695.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript.
    Source sequence(s)
    AK018646, AL772386, BC139138
    Consensus CDS
    CCDS37125.1
    UniProtKB/TrEMBL
    B2RT54, E9Q635, Q9D2Y0
    Related
    ENSMUSP00000134864.2, ENSMUST00000176074.9
    Conserved Domains (1) summary
    pfam05461
    Location:22 → 416
    ApoL; Apolipoprotein L

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    77272417..77283310 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011245766.1 → XP_011244068.1  apolipoprotein L 7a isoform X1

    See identical proteins and their annotated locations for XP_011244068.1

    UniProtKB/TrEMBL
    B2RT54, E9Q635, Q9D2Y0
    Conserved Domains (1) summary
    pfam05461
    Location:22 → 416
    ApoL; Apolipoprotein L
Nucleotide Protein Strain
Heading Accession and Version

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