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Ms4a18 membrane-spanning 4-domains, subfamily A, member 18 [ Mus musculus (house mouse) ]

Gene ID: 76002, updated on 2-Nov-2024

Summary

Official Symbol
Ms4a18provided by MGI
Official Full Name
membrane-spanning 4-domains, subfamily A, member 18provided by MGI
Primary source
MGI:MGI:1923252
See related
Ensembl:ENSMUSG00000094584 AllianceGenome:MGI:1923252
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
5033428B15Rik
Summary
Predicted to be involved in cell surface receptor signaling pathway. Predicted to be active in plasma membrane. Orthologous to human MS4A18 (membrane spanning 4-domains A18). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in large intestine adult (RPKM 56.0), duodenum adult (RPKM 24.1) and 1 other tissue See more
Orthologs
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Genomic context

See Ms4a18 in Genome Data Viewer
Location:
19 A; 19 7.5 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (10974388..10995390, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (10997024..11018026, complement)

Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene membrane-spanning 4-domains, subfamily A, member 10 Neighboring gene STARR-seq mESC enhancer starr_45563 Neighboring gene STARR-positive B cell enhancer ABC_E11021 Neighboring gene STARR-positive B cell enhancer mm9_chr19:11054242-11054543 Neighboring gene membrane-spanning 4-domains, subfamily A, member 15 Neighboring gene predicted gene 28347 Neighboring gene expressed sequence AW112010

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in cell surface receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
membrane-spanning 4-domains subfamily A member 18

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001251849.1NP_001238778.1  membrane-spanning 4-domains subfamily A member 18

    See identical proteins and their annotated locations for NP_001238778.1

    Status: VALIDATED

    Source sequence(s)
    AC148991, AK017199
    Consensus CDS
    CCDS57137.1
    UniProtKB/TrEMBL
    J3QN01
    Related
    ENSMUSP00000136529.2, ENSMUST00000177684.3
    Conserved Domains (1) summary
    pfam04103
    Location:152233
    CD20; CD20-like family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000085.7 Reference GRCm39 C57BL/6J

    Range
    10974388..10995390 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006527428.2XP_006527491.1  membrane-spanning 4-domains subfamily A member 18 isoform X1

    See identical proteins and their annotated locations for XP_006527491.1

    UniProtKB/TrEMBL
    J3QN01
    Conserved Domains (1) summary
    pfam04103
    Location:152233
    CD20; CD20-like family
  2. XM_006527429.2XP_006527492.1  membrane-spanning 4-domains subfamily A member 18 isoform X2

    Conserved Domains (1) summary
    pfam04103
    Location:155191
    CD20; CD20-like family