U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

dpp9 dipeptidyl-peptidase 9 [ Danio rerio (zebrafish) ]

Gene ID: 768170, updated on 12-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
dpp9provided by ZNC
Official Full Name
dipeptidyl-peptidase 9provided by ZNC
Primary source
ZFIN:ZDB-GENE-061013-777
See related
Ensembl:ENSDARG00000052606 AllianceGenome:ZFIN:ZDB-GENE-061013-777
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
im:7145318; zgc:152900
Summary
Predicted to enable dipeptidyl-peptidase activity. Predicted to act upstream of or within proteolysis. Orthologous to human DPP9 (dipeptidyl peptidase 9). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See dpp9 in Genome Data Viewer
Location:
chromosome: 8
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (47677180..47722065)
105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (47688187..47733073)

Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene phospholipase C, eta 2a Neighboring gene si:ch211-251b21.1 Neighboring gene si:ch211-243p7.3 Neighboring gene KN motif and ankyrin repeat domains 3 Neighboring gene NADH:ubiquinone oxidoreductase subunit A7

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. DPP9 deficiency: An inflammasomopathy that can be rescued by lowering NLRP1/IL-1 signaling. Harapas CR, et al. Sci Immunol, 2022 Sep 16. PMID 36112693, Free PMC Article
  2. A versatile gene trap to visualize and interrogate the function of the vertebrate proteome. Trinh le A, et al. Genes Dev, 2011 Nov 1. PMID 22056673, Free PMC Article
  3. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. DPP9 deficiency: An inflammasomopathy that can be rescued by lowering NLRP1/IL-1 signaling.
    Title: DPP9 deficiency: An inflammasomopathy that can be rescued by lowering NLRP1/IL-1 signaling.
Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables aminopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables dipeptidyl-peptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables dipeptidyl-peptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables peptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables serine-type peptidase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in proteolysis IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within proteolysis IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of inflammatory response IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within regulation of inflammatory response IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
dipeptidyl peptidase 9
NP_001070781.2
XP_005172542.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001077313.2 → NP_001070781.2  dipeptidyl peptidase 9

    Status: VALIDATED

    Source sequence(s)
    CR855877, CU499311
    UniProtKB/Swiss-Prot
    A0A2R8QP51, A0A8M1NBI9
    Related
    ENSDARP00000156382.1, ENSDART00000192605.1
    Conserved Domains (3) summary
    COG1506
    Location:526 → 885
    DAP2; Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism]
    pfam00326
    Location:684 → 885
    Peptidase_S9; Prolyl oligopeptidase family
    pfam00930
    Location:171 → 592
    DPPIV_N; Dipeptidyl peptidase IV (DPP IV) N-terminal region

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007119.7 Reference GRCz11 Primary Assembly

    Range
    47677180..47722065
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005172485.4 → XP_005172542.1  dipeptidyl peptidase 9 isoform X1

    UniProtKB/TrEMBL
    A0A8M2BJR8
    Related
    ENSDARP00000153678.1, ENSDART00000187320.1
    Conserved Domains (3) summary
    COG1506
    Location:525 → 884
    DAP2; Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism]
    pfam00326
    Location:683 → 884
    Peptidase_S9; Prolyl oligopeptidase family
    pfam00930
    Location:171 → 591
    DPPIV_N; Dipeptidyl peptidase IV (DPP IV) N-terminal region
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A2R8QP51.1 GenPept UniProtKB/Swiss-Prot:A0A2R8QP51

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools