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Arxes2 adipocyte-related X-chromosome expressed sequence 2 [ Mus musculus (house mouse) ]

Gene ID: 76976, updated on 2-Nov-2024

Summary

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Official Symbol
Arxes2provided by MGI
Official Full Name
adipocyte-related X-chromosome expressed sequence 2provided by MGI
Primary source
MGI:MGI:1924226
See related
Ensembl:ENSMUSG00000048040 AllianceGenome:MGI:1924226
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Spcs3; Spc22/23; 2900062L11Rik
Summary
Acts upstream of or within fat cell differentiation. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See Arxes2 in Genome Data Viewer
Location:
X F1; X 57.35 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (134894569..134896108)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (135993820..135995359)

Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene G protein-coupled receptor associated sorting protein 2 Neighboring gene basic helix-loop-helix domain containing, class B9 Neighboring gene STARR-seq mESC enhancer starr_47972 Neighboring gene predicted gene, 31214 Neighboring gene adipocyte-related X-chromosome expressed sequence 1 Neighboring gene predicted gene, 54084

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Arxes: retrotransposed genes required for adipogenesis. Prokesch A, et al. Nucleic Acids Res, 2011 Apr. PMID 21177646, Free PMC Article
  2. A 1.1-Mb segmental deletion on the X chromosome causes meiotic failure in male mice. Zhou J, et al. Biol Reprod, 2013 Jun. PMID 23677977, Free PMC Article
  3. Lineage-specific biology revealed by a finished genome assembly of the mouse. Church DM, et al. PLoS Biol, 2009 May 5. PMID 19468303, Free PMC Article
  4. Targeting a complex transcriptome: the construction of the mouse full-length cDNA encyclopedia. Carninci P, et al. Genome Res, 2003 Jun. PMID 12819125, Free PMC Article
  5. A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome. Mural RJ, et al. Science, 2002 May 31. PMID 12040188

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Process Evidence Code Pubs
acts_upstream_of_or_within fat cell differentiation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in protein targeting to ER IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in signal peptide processing IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in signal peptide processing IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum IDA
Inferred from Direct Assay
more info
 PubMed 
part_of signal peptidase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of signal peptidase complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
adipocyte-related X-chromosome expressed sequence 2
Names
SPase 22 kDa subunit
SPase 22/23 kDa subunit
microsomal signal peptidase 22/23 kDa subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_029823.2 → NP_084099.1  adipocyte-related X-chromosome expressed sequence 2

    See identical proteins and their annotated locations for NP_084099.1

    Status: VALIDATED

    Source sequence(s)
    AA286632, AK077432, AV333270, BY773138
    Consensus CDS
    CCDS30411.1
    UniProtKB/Swiss-Prot
    B1AUR7, C0HK79, C0HK80, Q8BK31, Q9D365, Q9D6F2
    Related
    ENSMUSP00000051250.8, ENSMUST00000058119.9
    Conserved Domains (1) summary
    pfam04573
    Location:4 → 173
    SPC22; Signal peptidase subunit

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000086.8 Reference GRCm39 C57BL/6J

    Range
    134894569..134896108
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NR_003642.1: Suppressed sequence

    Description
    NR_003642.1: This RefSeq was permanently suppressed because it is now thought that this gene encodes a protein.
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
C0HK80.1 GenPept UniProtKB/Swiss-Prot:C0HK80

Gene LinkOut

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