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Prr15 proline rich 15 [ Mus musculus (house mouse) ]

Gene ID: 78004, updated on 2-Nov-2024

Summary

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Official Symbol
Prr15provided by MGI
Official Full Name
proline rich 15provided by MGI
Primary source
MGI:MGI:1925254
See related
Ensembl:ENSMUSG00000045725 AllianceGenome:MGI:1925254
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
G90; E130201N16Rik
Summary
Is expressed in several structures, including alimentary system; bone; central nervous system; lung; and sensory organ. Orthologous to human PRR15 (proline rich 15). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in duodenum adult (RPKM 38.6), small intestine adult (RPKM 37.2) and 6 other tissues See more
Orthologs
human all
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Genomic context

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See Prr15 in Genome Data Viewer
Location:
6 B3; 6 26.88 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (54290442..54320421)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (54326756..54343436)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene chimerin 2 Neighboring gene STARR-seq mESC enhancer starr_15947 Neighboring gene 60S ribosomal protein L29 pseudogene Neighboring gene RIKEN cDNA 9130019P16 gene Neighboring gene predicted gene 15527 Neighboring gene STARR-seq mESC enhancer starr_15949 Neighboring gene STARR-seq mESC enhancer starr_15950 Neighboring gene predicted gene, 34169 Neighboring gene WAS/WASL interacting protein family, member 3 Neighboring gene predicted gene, 44026 Neighboring gene secernin 1 Neighboring gene predicted gene, 52863

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Identification and characterization of G90, a novel mouse RNA that lacks an extensive open reading frame. Krause R, et al. Gene, 1999 May 17. PMID 10333519
  2. PRR15 deficiency facilitates malignant progression by mediating PI3K/Akt signaling and predicts clinical prognosis in triple-negative rather than non-triple-negative breast cancer. Guo F, et al. Cell Death Dis, 2023 Apr 18. PMID 37072408, Free PMC Article
  3. Preferential expression of the G90 gene in post-mitotic cells during mouse embryonic development. Meunier D, et al. Anat Embryol (Berl), 2003 Sep. PMID 12768423
  4. Spatial and temporal analysis of gene expression during growth and fusion of the mouse facial prominences. Feng W, et al. PLoS One, 2009 Dec 16. PMID 20016822, Free PMC Article
  5. Etv1 Controls the Establishment of Non-overlapping Motor Innervation of Neighboring Facial Muscles during Development. Tenney AP, et al. Cell Rep, 2019 Oct 8. PMID 31597102, Free PMC Article

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. PRR15 deficiency facilitates malignant progression by mediating PI3K/Akt signaling and predicts clinical prognosis in triple-negative rather than non-triple-negative breast cancer.
    Title: PRR15 deficiency facilitates malignant progression by mediating PI3K/Akt signaling and predicts clinical prognosis in triple-negative rather than non-triple-negative breast cancer.
  2. G90 expression and absence of proliferation were correlated in most of the cells showing expression of this gene during embryonic development in mice.
    Title: Preferential expression of the G90 gene in post-mitotic cells during mouse embryonic development.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
proline-rich protein 15

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_030024.3 → NP_084300.1  proline-rich protein 15

    See identical proteins and their annotated locations for NP_084300.1

    Status: VALIDATED

    Source sequence(s)
    AC084220
    Consensus CDS
    CCDS20155.1
    UniProtKB/Swiss-Prot
    Q9D1T5
    UniProtKB/TrEMBL
    A2RT92
    Related
    ENSMUSP00000049549.5, ENSMUST00000059138.6
    Conserved Domains (1) summary
    pfam15321
    Location:10 → 102
    ATAD4; ATPase family AAA domain containing 4

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    54290442..54320421
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036152399.1 → XP_036008292.1  proline-rich protein 15 isoform X1

    UniProtKB/Swiss-Prot
    Q9D1T5
    UniProtKB/TrEMBL
    A2RT92
    Conserved Domains (1) summary
    pfam15321
    Location:10 → 102
    ATAD4; ATPase family AAA domain containing 4

RNA

  1. XR_004933647.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9D1T5.1 GenPept UniProtKB/Swiss-Prot:Q9D1T5

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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