U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Nxpe2 neurexophilin and PC-esterase domain family, member 2 [ Mus musculus (house mouse) ]

Gene ID: 78252, updated on 28-Oct-2024

Summary

Go to the top of the page Help
Official Symbol
Nxpe2provided by MGI
Official Full Name
neurexophilin and PC-esterase domain family, member 2provided by MGI
Primary source
MGI:MGI:1925502
See related
Ensembl:ENSMUSG00000032028 AllianceGenome:MGI:1925502
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Fam55b; 4432416J03Rik
Summary
Predicted to be located in membrane. Is expressed in several structures, including ganglia; limb; pituitary gland; sensory organ; and skeletal musculature. Orthologous to human NXPE2 (neurexophilin and PC-esterase domain family member 2). [provided by Alliance of Genome Resources, Oct 2024]
Expression
Biased expression in liver E14 (RPKM 35.9), liver E14.5 (RPKM 33.4) and 4 other tissues See more
Orthologs
human all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Nxpe2 in Genome Data Viewer
Location:
9 A5.3; 9 26.38 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (48229303..48264749, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (48318003..48353449, complement)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene neurexophilin and PC-esterase domain family, member 4 Neighboring gene predicted gene, 57543 Neighboring gene STARR-positive B cell enhancer mm9_chr9:48025608-48025909 Neighboring gene predicted gene, 51672 Neighboring gene STARR-seq mESC enhancer starr_24065 Neighboring gene neurexophilin and PC-esterase domain family, member 1, pseudogene Neighboring gene predicted gene, 32131 Neighboring gene NHP2 non-histone chromosome protein 2-like 1 pseudogene

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Identification of candidate genes in the type 2 diabetes modifier locus using expression QTL. Yaguchi H, et al. Genomics, 2005 May. PMID 15820311
  2. A mouse knockout library for secreted and transmembrane proteins. Tang T, et al. Nat Biotechnol, 2010 Jul. PMID 20562862
  3. BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. Magdaleno S, et al. PLoS Biol, 2006 Apr. PMID 16602821, Free PMC Article
  4. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article
  5. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
NXPE family member 2
Names
family with sequence similarity 55, member B
protein FAM55B

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001428899.1 → NP_001415828.1  NXPE family member 2 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC154373

  2. NM_001428900.1 → NP_001415829.1  NXPE family member 2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC154373

  3. NM_030069.4 → NP_084345.2  NXPE family member 2 isoform 1

    See identical proteins and their annotated locations for NP_084345.2

    Status: VALIDATED

    Source sequence(s)
    AC154373
    Consensus CDS
    CCDS23151.1
    UniProtKB/Swiss-Prot
    B2RU41, Q3U095, Q8BM95, Q9CX72
    UniProtKB/TrEMBL
    A0A0R4J0E5
    Related
    ENSMUSP00000034527.8, ENSMUST00000034527.14
    Conserved Domains (1) summary
    pfam06312
    Location:141 → 269
    Neurexophilin; Neurexophilin

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    48229303..48264749 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017313695.3 → XP_017169184.1  NXPE family member 2 isoform X1

    UniProtKB/Swiss-Prot
    B2RU41, Q3U095, Q8BM95, Q9CX72
    Conserved Domains (1) summary
    pfam06312
    Location:142 → 270
    Neurexophilin

  2. XM_006510693.4 → XP_006510756.1  NXPE family member 2 isoform X2

    UniProtKB/Swiss-Prot
    B2RU41, Q3U095, Q8BM95, Q9CX72
    Conserved Domains (1) summary
    pfam06312
    Location:141 → 269
    Neurexophilin

  3. XM_006510694.4 → XP_006510757.1  NXPE family member 2 isoform X3

    Conserved Domains (1) summary
    pfam06312
    Location:96 → 224
    Neurexophilin

  4. XM_017313696.3 → XP_017169185.1  NXPE family member 2 isoform X4

    Conserved Domains (1) summary
    pfam06312
    Location:142 → 270
    Neurexophilin

  5. XM_006510696.4 → XP_006510759.1  NXPE family member 2 isoform X5

    Conserved Domains (1) summary
    pfam06312
    Location:141 → 269
    Neurexophilin
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q3U095.1 GenPept UniProtKB/Swiss-Prot:Q3U095

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools