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Bcam basal cell adhesion molecule (Lutheran blood group) [ Rattus norvegicus (Norway rat) ]

Gene ID: 78958, updated on 2-Nov-2024

Summary

Official Symbol
Bcamprovided by RGD
Official Full Name
basal cell adhesion molecule (Lutheran blood group)provided by RGD
Primary source
RGD:68378
See related
EnsemblRapid:ENSRNOG00000029399 AllianceGenome:RGD:68378
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Lu
Summary
Predicted to enable laminin binding activity and laminin receptor activity. Predicted to be involved in cell-matrix adhesion. Predicted to act upstream of or within cell adhesion. Predicted to be located in cell surface. Predicted to be active in plasma membrane. Orthologous to human BCAM (basal cell adhesion molecule (Lutheran blood group)). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Lung (RPKM 1098.4), Heart (RPKM 641.2) and 6 other tissues See more
Orthologs
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Genomic context

See Bcam in Genome Data Viewer
Location:
1q21
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (88542971..88557358, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (79415016..79429403, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (80674463..80689122, complement)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene translocase of outer mitochondrial membrane 40 Neighboring gene nectin cell adhesion molecule 2 Neighboring gene Cbl proto-oncogene C Neighboring gene BCL3, transcription coactivator

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables laminin binding IEA
Inferred from Electronic Annotation
more info
 
enables laminin binding ISO
Inferred from Sequence Orthology
more info
 
enables laminin receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables laminin receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables laminin receptor activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within cell adhesion ISO
Inferred from Sequence Orthology
more info
 
involved_in cell adhesion NAS
Non-traceable Author Statement
more info
PubMed 
involved_in cell-matrix adhesion IEA
Inferred from Electronic Annotation
more info
 
involved_in cell-matrix adhesion ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in cell surface IEA
Inferred from Electronic Annotation
more info
 
located_in cell surface ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
basal cell adhesion molecule
Names
B-CAM cell surface glycoprotein
Lutheran blood group (Auberger b antigen included)
lutheran antigen

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_031752.2NP_113940.1  basal cell adhesion molecule precursor

    See identical proteins and their annotated locations for NP_113940.1

    Status: PROVISIONAL

    Source sequence(s)
    BC072479
    UniProtKB/Swiss-Prot
    Q9ESS6
    UniProtKB/TrEMBL
    A0A8I6A1Q0
    Related
    ENSRNOP00000047809.4, ENSRNOT00000045574.6
    Conserved Domains (4) summary
    smart00408
    Location:376424
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:32137
    IG_like; Immunoglobulin like
    pfam08205
    Location:145242
    C2-set_2; CD80-like C2-set immunoglobulin domain
    cl11960
    Location:448522
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    88542971..88557358 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)