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PRMT1 histone arginine methyltransferase PRMT1 [ Toxoplasma gondii ME49 ]

Gene ID: 7896799, updated on 17-May-2024

Summary

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Gene symbol
PRMT1
Gene description
histone arginine methyltransferase PRMT1
Locus tag
TGME49_219520
See related
ToxoDB:TGME49_219520; VEuPathDB:TGME49_219520
Gene type
protein coding
RNA name
histone arginine methyltransferase PRMT1
RefSeq status
PROVISIONAL
Organism
Toxoplasma gondii ME49 (strain: ME49)
Lineage
Eukaryota; Alveolata; Apicomplexa; Conoidasida; Coccidia; Eucoccidiorida; Eimeriorina; Sarcocystidae; Toxoplasma
Old locus tag
TGME49_019520
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Genomic context

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Location:
chromosome: XII
Exon count:
5
Sequence:
Chromosome: XII; NC_031480.1 (885564..889987, complement)

Chromosome XII - NC_031480.1Genomic Context describing neighboring genes Neighboring gene cytosolic tRNA-Ala synthetase Neighboring gene hypothetical protein Neighboring gene GTP binding protein 7 isoform 2 family protein, putative Neighboring gene hypothetical protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_031480.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Comparative Monomethylarginine Proteomics Suggests that Protein Arginine Methyltransferase 1 (PRMT1) is a Significant Contributor to Arginine Monomethylation in Toxoplasma gondii. Yakubu RR, et al. Mol Cell Proteomics, 2017 Apr. PMID 28143887, Free PMC Article
  2. PRMT1 methylates the single Argonaute of Toxoplasma gondii and is important for the recruitment of Tudor nuclease for target RNA cleavage by antisense guide RNA. Musiyenko A, et al. Cell Microbiol, 2012 Jun. PMID 22309152, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Data highlight the importance of PRMT1 in arginine methylation in T. gondii, as one of the potential regulator of a large number of processes including RNA biology and transcription.
    Title: Comparative Monomethylarginine Proteomics Suggests that Protein Arginine Methyltransferase 1 (PRMT1) is a Significant Contributor to Arginine Monomethylation in Toxoplasma gondii.
  2. the parasitic PRMT1 plays multiple roles, and its loss affects the recruitment of a more potent second slicer to the parasitic RNA silencing complex
    Title: PRMT1 methylates the single Argonaute of Toxoplasma gondii and is important for the recruitment of Tudor nuclease for target RNA cleavage by antisense guide RNA.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein-arginine N-methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in peptidyl-arginine methylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Names
histone arginine methyltransferase PRMT1
XP_002370706.1
  • encoded by transcript TGME49_219520
    Gene product name based on ToxoDB Community Expert Annotation.

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_031480.1 Reference assembly

    Range
    885564..889987 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002370665.2 → XP_002370706.1  histone arginine methyltransferase PRMT1 [Toxoplasma gondii ME49]

    See identical proteins and their annotated locations for XP_002370706.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A086K1Y8, A0A086KTK3, A0A086L2V9, A0A086M7N7, A0A086QSY8, A0A0F7V6G6, A0A125YYW7, A0A125YYW8, A0A139Y9M2, A0A2G8XPA4, A0A2T6ITZ7, A0A3R7YRR7, B6KS83, B9PQN6, B9QLS1, Q2VTP7, S7V1R3, S8EUF6
    Conserved Domains (1) summary
    pfam13649
    Location:111 → 208
    Methyltransf_25; Methyltransferase domain
Nucleotide Protein
Heading Accession and Version

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