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nanog - nanog homeobox

Enables several functions, including DNA-binding transcription factor activity; chromatin binding activity; and identical protein binding activity. Involved in nucleosome organization. Acts upstream of or within with a positive effect on yolk syncytial layer development. Acts upstream of or within several processes, including cytoskeleton organization; negative regulation of beta-catenin-TCF complex assembly; and negative regulation of canonical Wnt signaling pathway. Predicted to be located in nucleus. Is expressed in several structures, including blastoderm; blastodisc; neuronal stem cell; reproductive system; and unfertilized egg. Orthologous to several human genes including NANOG (Nanog homeobox) and NANOGP1 (Nanog homeobox pseudogene 1). [provided by Alliance of Genome Resources, Oct 2024]

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Species Gene Architecture aa