U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Igsf6 immunoglobulin superfamily, member 6 [ Mus musculus (house mouse) ]

Gene ID: 80719, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
Igsf6provided by MGI
Official Full Name
immunoglobulin superfamily, member 6provided by MGI
Primary source
MGI:MGI:1891393
See related
Ensembl:ENSMUSG00000035004 AllianceGenome:MGI:1891393
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to be located in membrane. Orthologous to human IGSF6 (immunoglobulin superfamily member 6). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Broad expression in liver E18 (RPKM 6.0), liver E14 (RPKM 3.2) and 19 other tissues See more
Orthologs
human all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Igsf6 in Genome Data Viewer
Location:
7 F2; 7 65.07 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (120663290..120673753, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (121064067..121074581, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene methyltransferase like 9 Neighboring gene predicted gene, 27991 Neighboring gene 60S ribosomal protein L32 pseudogene Neighboring gene otoancorin Neighboring gene STARR-seq mESC enhancer starr_20059 Neighboring gene src family associated phosphoprotein 2 pseudogene

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Characterization of the human PAP1 gene and its homologue possible involvement in mouse embryonic development. Shu KX, et al. Colloids Surf B Biointerfaces, 2006 Sep 1. PMID 16837177
  2. The mouse and human IGSF6 (DORA) genes map to the inflammatory bowel disease 1 locus and are embedded in an intron of a gene of unknown function. Bates EE, et al. Immunogenetics, 2000 Nov. PMID 11132146
  3. BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING). Motani K, et al. J Biol Chem, 2020 Aug 7. PMID 32554809, Free PMC Article
  4. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
  5. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

Pathways from PubChem

Go to the top of the page

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
immunoglobulin superfamily member 6

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_030691.1 → NP_109616.1  immunoglobulin superfamily member 6 precursor

    See identical proteins and their annotated locations for NP_109616.1

    Status: PROVISIONAL

    Source sequence(s)
    AJ278575
    Consensus CDS
    CCDS21801.1
    UniProtKB/Swiss-Prot
    P0C6B7
    Related
    ENSMUSP00000039059.3, ENSMUST00000047194.4
    Conserved Domains (2) summary
    smart00410
    Location:35 → 141
    IG_like; Immunoglobulin like
    cl11960
    Location:35 → 142
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    120663290..120673753 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P0C6B7.1 GenPept UniProtKB/Swiss-Prot:P0C6B7

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools