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Pum1 pumilio RNA-binding family member 1 [ Mus musculus (house mouse) ]

Gene ID: 80912, updated on 2-Nov-2024

Summary

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Official Symbol
Pum1provided by MGI
Official Full Name
pumilio RNA-binding family member 1provided by MGI
Primary source
MGI:MGI:1931749
See related
Ensembl:ENSMUSG00000028580 AllianceGenome:MGI:1931749
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Pumm; mKIAA0099
Summary
Enables mRNA 3'-UTR binding activity. Involved in several processes, including adult locomotory behavior; post-transcriptional regulation of gene expression; and spermatogenesis. Acts upstream of or within post-transcriptional regulation of gene expression. Located in cytoplasm. Is expressed in several structures, including central nervous system; intestine; olfactory epithelium; retina; and testis. Human ortholog(s) of this gene implicated in cerebellar ataxia type 47. Orthologous to human PUM1 (pumilio RNA binding family member 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in ovary adult (RPKM 32.2), whole brain E14.5 (RPKM 27.8) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Pum1 in Genome Data Viewer
Location:
4 D2.2; 4 63.43 cM
Exon count:
22
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (130390509..130508875)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (130663238..130781564)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene Na+/K+ transporting ATPase interacting 1 Neighboring gene STARR-seq mESC enhancer starr_11526 Neighboring gene STARR-seq mESC enhancer starr_11530 Neighboring gene predicted gene, 53228 Neighboring gene STARR-seq mESC enhancer starr_11531 Neighboring gene STARR-seq mESC enhancer starr_11533 Neighboring gene small nucleolar RNA, C/D box 85 Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:130330830-130331017 Neighboring gene predicted gene, 24091 Neighboring gene STARR-positive B cell enhancer ABC_E6227 Neighboring gene predicted gene, 23711 Neighboring gene predicted gene 12972 Neighboring gene syndecan 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Dosage sensitivity to Pumilio1 variants in the mouse brain reflects distinct molecular mechanisms. Botta S, et al. EMBO J, 2023 Jun 1. PMID 37070548, Free PMC Article
  2. Loss of preimplantation embryo resulting from a Pum1 gene trap mutation. Zhang C, et al. Biochem Biophys Res Commun, 2015 Jun 19. PMID 25896760
  3. A role of Pumilio 1 in mammalian oocyte maturation and maternal phase of embryogenesis. Mak W, et al. Cell Biosci, 2018. PMID 30364263, Free PMC Article
  4. Modular recognition of RNA by a human pumilio-homology domain. Wang X, et al. Cell, 2002 Aug 23. PMID 12202039
  5. PUMILIO proteins promote colorectal cancer growth via suppressing p21. Gong Y, et al. Nat Commun, 2022 Mar 25. PMID 35338151, Free PMC Article

See all (62) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Dosage sensitivity to Pumilio1 variants in the mouse brain reflects distinct molecular mechanisms.
    Title: Dosage sensitivity to Pumilio1 variants in the mouse brain reflects distinct molecular mechanisms.
  2. Sertoli cell PUMILIO proteins modulate mouse testis size through translational control of cell cycle regulators.
    Title: Sertoli cell PUMILIO proteins modulate mouse testis size through translational control of cell cycle regulators.
  3. Changes in subcellular structures and states of pumilio 1 regulate the translation of target Mad2 and cyclin B1 mRNAs.
    Title: Changes in subcellular structures and states of pumilio 1 regulate the translation of target Mad2 and cyclin B1 mRNAs.
  4. Pum1 and Pum2 achieve these two complementary aspects of pluripotency by forming a negative interregulatory feedback loop that directly regulates at least 1,486 mRNAs. Pum1 and Pum2 regulate target mRNAs not only by repressing translation, but also by promoting translation and enhancing or reducing mRNA stability of different target mRNAs.
    Title: Pumilio proteins utilize distinct regulatory mechanisms to achieve complementary functions required for pluripotency and embryogenesis.
  5. Pum1 and Pum2 regulate mouse body and organ size by post-transcriptional repression of the cell cycle inhibitor Cdkn1b.
    Title: Mammalian Pum1 and Pum2 Control Body Size via Translational Regulation of the Cell Cycle Inhibitor Cdkn1b.
  6. major role of Pum1 and Pum2 in hippocampal neurogenesis and function
    Title: Post-transcriptional regulation of mouse neurogenesis by Pumilio proteins.
  7. important role in the establishment of the primordial follicle pool, meiosis, and female reproductive competency
    Title: An Important Role of Pumilio 1 in Regulating the Development of the Mammalian Female Germline.
  8. Data indicate a role for RNA-binding protein Pum1 in early embryonic development.
    Title: Loss of preimplantation embryo resulting from a Pum1 gene trap mutation.
  9. The RNA-binding protein PUMILIO1 (PUM1) not only directly regulates ATAXIN1 but also plays an unexpectedly important role in neuronal function. Loss of Pum1 caused progressive motor dysfunction and SCA1-like neurodegeneration with motor impairment, primarily by increasing Ataxin1 levels.
    Title: Pumilio1 haploinsufficiency leads to SCA1-like neurodegeneration by increasing wild-type Ataxin1 levels.
  10. Key components of the p53 pathway are coordinately regulated by Pumilio 1 at the posttranscriptional level, which may exemplify an RNA operon.
    Title: Pumilio 1 suppresses multiple activators of p53 to safeguard spermatogenesis.
Submit: New GeneRIF Correction See all GeneRIFs (11)

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 
  • Gene trapped (3) 
  • Targeted (5)  1 citation

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA binding ISO
Inferred from Sequence Orthology
more info
  
enables mRNA 3'-UTR binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables mRNA 3'-UTR binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables mRNA 3'-UTR binding ISO
Inferred from Sequence Orthology
more info
  
enables miRNA binding IEA
Inferred from Electronic Annotation
more info
  
enables miRNA binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in adult locomotory behavior IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in mRNA destabilization IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in miRNA processing IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in miRNA processing ISO
Inferred from Sequence Orthology
more info
  
involved_in miRNA processing ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in positive regulation of RIG-I signaling pathway IEA
Inferred from Electronic Annotation
more info
  
involved_in positive regulation of RIG-I signaling pathway ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of miRNA-mediated gene silencing ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of miRNA-mediated gene silencing ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in post-transcriptional gene silencing IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within post-transcriptional regulation of gene expression IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within post-transcriptional regulation of gene expression ISO
Inferred from Sequence Orthology
more info
 PubMed 
acts_upstream_of_positive_effect post-transcriptional regulation of gene expression ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of cell cycle ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of cell cycle ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in regulation of chromosome segregation ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of chromosome segregation ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in regulation of mRNA stability IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of mRNA stability ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of translation IEA
Inferred from Electronic Annotation
more info
  
involved_in spermatogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in stem cell differentiation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in P-body ISO
Inferred from Sequence Orthology
more info
  
located_in P-body ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in axon IEA
Inferred from Electronic Annotation
more info
  
located_in axon ISO
Inferred from Sequence Orthology
more info
  
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasmic stress granule IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasmic stress granule ISO
Inferred from Sequence Orthology
more info
  
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytosol IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
pumilio homolog 1
Names
pumilio 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001159603.2 → NP_001153075.1  pumilio homolog 1 isoform 2

    See identical proteins and their annotated locations for NP_001153075.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses multiple alternate in-frame splice sites, compared to variant 1, which results in a shorter protein (isoform 2), compared to isoform 1.
    Source sequence(s)
    AK162742, BE653001, BU708930, BY782432, CB724122, CF157665, CF746520, CJ064695, CJ227969, CN530452, CN530471, CN538180, CN724656, CV559585
    Consensus CDS
    CCDS51311.1
    UniProtKB/TrEMBL
    Q3UR00
    Related
    ENSMUSP00000095476.3, ENSMUST00000097864.9
    Conserved Domains (1) summary
    cd07920
    Location:843 → 1164
    Pumilio; Pumilio-family RNA binding domain

  2. NM_001159604.2 → NP_001153076.1  pumilio homolog 1 isoform 3

    See identical proteins and their annotated locations for NP_001153076.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) uses an alternate in-frame splice site, compared to variant 1, which results in a shorter protein (isoform 3), compared to isoform 1.
    Source sequence(s)
    AK161135, AK162742, BC048174, BY782432, CF746520, CJ227969
    Consensus CDS
    CCDS51312.1
    UniProtKB/TrEMBL
    Q3TQ21, Q3UR00
    Related
    ENSMUSP00000095474.3, ENSMUST00000097862.3
    Conserved Domains (1) summary
    cd07920
    Location:843 → 1166
    Pumilio; Pumilio-family RNA binding domain

  3. NM_001159605.2 → NP_001153077.1  pumilio homolog 1 isoform 4

    See identical proteins and their annotated locations for NP_001153077.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) has multiple coding region differences, compared to variant 1, which results in a shorter protein (isoform 4), compared to isoform 1.
    Source sequence(s)
    AK161135, AK162742, BY782432, CF746520, CJ227969
    Consensus CDS
    CCDS51313.1
    UniProtKB/TrEMBL
    Q3TTW5, Q3UR00
    Related
    ENSMUSP00000101613.3, ENSMUST00000105992.9
    Conserved Domains (1) summary
    cd07920
    Location:747 → 1070
    Pumilio; Pumilio-family RNA binding domain

  4. NM_001159606.2 → NP_001153078.1  pumilio homolog 1 isoform 5

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) has multiple coding region differences, compared to variant 1, which results in a shorter protein (isoform 5), compared to isoform 1.
    Source sequence(s)
    AK147185, AK161135, AK162742, BY782432, CF746520, CJ227969, CN526490
    Consensus CDS
    CCDS51314.1
    UniProtKB/TrEMBL
    E9Q6M7, Q3UHW0
    Related
    ENSMUSP00000101612.3, ENSMUST00000105991.9
    Conserved Domains (1) summary
    cd07920
    Location:601 → 922
    Pumilio; Pumilio-family RNA binding domain

  5. NM_001356564.1 → NP_001343493.1  pumilio homolog 1 isoform 6

    Status: VALIDATED

    Source sequence(s)
    AK162742, AL627104, CF746520, CJ227969
    UniProtKB/TrEMBL
    Q3TRI4
    Conserved Domains (1) summary
    cd07920
    Location:765 → 1086
    Pumilio; Pumilio-family RNA binding domain

  6. NM_001356565.1 → NP_001343494.1  pumilio homolog 1 isoform 7

    Status: VALIDATED

    Source sequence(s)
    AK162742, AL627104, BY782432, CF746520, CJ227969, CN456820, CN724656, CV559585
    UniProtKB/TrEMBL
    Q3UR00
    Conserved Domains (1) summary
    cd07920
    Location:747 → 1068
    Pumilio; Pumilio-family RNA binding domain

  7. NM_001356566.1 → NP_001343495.1  pumilio homolog 1 isoform 8

    Status: VALIDATED

    Source sequence(s)
    AK162742, AL627104, BE653001, BY782432, CF746520, CJ093090, CJ227969, CN724656, CV559585
    UniProtKB/TrEMBL
    Q3UHW0
    Conserved Domains (1) summary
    cd07920
    Location:601 → 924
    Pumilio; Pumilio-family RNA binding domain

  8. NM_030722.3 → NP_109647.2  pumilio homolog 1 isoform 1

    See identical proteins and their annotated locations for NP_109647.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    AK162742, BE653001, BU708930, BY782432, CB724122, CF746520, CJ064695, CJ227969, CN530452, CN530471, CN538180, CN724656
    Consensus CDS
    CCDS18710.1
    UniProtKB/Swiss-Prot
    Q80U78, Q80X96, Q80YU8, Q8BPV7, Q9EPU6
    UniProtKB/TrEMBL
    Q3UR00
    Related
    ENSMUSP00000030315.7, ENSMUST00000030315.13
    Conserved Domains (1) summary
    cd07920
    Location:844 → 1167
    Pumilio; Pumilio-family RNA binding domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    130390509..130508875
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006539291.5 → XP_006539354.1  pumilio homolog 1 isoform X1

    See identical proteins and their annotated locations for XP_006539354.1

    UniProtKB/TrEMBL
    Q3UR00
    Conserved Domains (1) summary
    cd07920
    Location:848 → 1171
    Pumilio; Pumilio-family RNA binding domain

  2. XM_006539294.5 → XP_006539357.1  pumilio homolog 1 isoform X3

    See identical proteins and their annotated locations for XP_006539357.1

    UniProtKB/TrEMBL
    Q3UR00
    Conserved Domains (1) summary
    cd07920
    Location:848 → 1169
    Pumilio; Pumilio-family RNA binding domain

  3. XM_006539296.5 → XP_006539359.1  pumilio homolog 1 isoform X10

    See identical proteins and their annotated locations for XP_006539359.1

    UniProtKB/TrEMBL
    Q3TRI4
    Conserved Domains (1) summary
    cd07920
    Location:769 → 1092
    Pumilio; Pumilio-family RNA binding domain

  4. XM_006539297.5 → XP_006539360.1  pumilio homolog 1 isoform X11

    See identical proteins and their annotated locations for XP_006539360.1

    UniProtKB/TrEMBL
    Q3TRI4
    Conserved Domains (1) summary
    cd07920
    Location:769 → 1090
    Pumilio; Pumilio-family RNA binding domain

  5. XM_017320459.3 → XP_017175948.1  pumilio homolog 1 isoform X6

    UniProtKB/TrEMBL
    Q3UR00
    Conserved Domains (1) summary
    cd07920
    Location:844 → 1165
    Pumilio; Pumilio-family RNA binding domain

  6. XM_006539295.5 → XP_006539358.1  pumilio homolog 1 isoform X8

    See identical proteins and their annotated locations for XP_006539358.1

    UniProtKB/TrEMBL
    Q3UR00
    Conserved Domains (1) summary
    cd07920
    Location:809 → 1132
    Pumilio; Pumilio-family RNA binding domain

  7. XM_030253924.2 → XP_030109784.1  pumilio homolog 1 isoform X9

    UniProtKB/TrEMBL
    Q3UR00
    Conserved Domains (1) summary
    cd07920
    Location:809 → 1130
    Pumilio; Pumilio-family RNA binding domain

  8. XM_036164565.1 → XP_036020458.1  pumilio homolog 1 isoform X21

    UniProtKB/TrEMBL
    Q3TRI4
    Conserved Domains (1) summary
    cd07920
    Location:730 → 1053
    Pumilio; Pumilio-family RNA binding domain

  9. XM_030253933.2 → XP_030109793.1  pumilio homolog 1 isoform X32

    UniProtKB/TrEMBL
    Q3TRI4
    Conserved Domains (1) summary
    cd07920
    Location:730 → 1051
    Pumilio; Pumilio-family RNA binding domain

  10. XM_006539303.5 → XP_006539366.1  pumilio homolog 1 isoform X31

    See identical proteins and their annotated locations for XP_006539366.1

    UniProtKB/TrEMBL
    Q3U4T5
    Conserved Domains (1) summary
    cd07920
    Location:659 → 982
    Pumilio; Pumilio-family RNA binding domain

  11. XM_006539293.5 → XP_006539356.1  pumilio homolog 1 isoform X2

    See identical proteins and their annotated locations for XP_006539356.1

    UniProtKB/TrEMBL
    Q3UR00
    Conserved Domains (1) summary
    cd07920
    Location:847 → 1170
    Pumilio; Pumilio-family RNA binding domain

  12. XM_030253922.2 → XP_030109782.1  pumilio homolog 1 isoform X5

    UniProtKB/TrEMBL
    Q3UR00
    Conserved Domains (1) summary
    cd07920
    Location:843 → 1166
    Pumilio; Pumilio-family RNA binding domain

  13. XM_036164562.1 → XP_036020455.1  pumilio homolog 1 isoform X15

    UniProtKB/TrEMBL
    Q3UR00
    Conserved Domains (1) summary
    cd07920
    Location:843 → 1164
    Pumilio; Pumilio-family RNA binding domain

  14. XM_030253923.2 → XP_030109783.1  pumilio homolog 1 isoform X7

    UniProtKB/TrEMBL
    Q3UR00
    Conserved Domains (1) summary
    cd07920
    Location:842 → 1165
    Pumilio; Pumilio-family RNA binding domain

  15. XM_036164564.1 → XP_036020457.1  pumilio homolog 1 isoform X17

    UniProtKB/TrEMBL
    Q3UR00
    Conserved Domains (1) summary
    cd07920
    Location:842 → 1163
    Pumilio; Pumilio-family RNA binding domain

  16. XM_006539299.5 → XP_006539362.1  pumilio homolog 1 isoform X18

    See identical proteins and their annotated locations for XP_006539362.1

    UniProtKB/TrEMBL
    Q3UR00
    Conserved Domains (1) summary
    cd07920
    Location:752 → 1075
    Pumilio; Pumilio-family RNA binding domain

  17. XM_030253931.2 → XP_030109791.1  pumilio homolog 1 isoform X28

    UniProtKB/TrEMBL
    Q3UR00
    Conserved Domains (1) summary
    cd07920
    Location:752 → 1073
    Pumilio; Pumilio-family RNA binding domain

  18. XM_030253925.2 → XP_030109785.1  pumilio homolog 1 isoform X19

    UniProtKB/TrEMBL
    Q3UR00
    Conserved Domains (1) summary
    cd07920
    Location:748 → 1071
    Pumilio; Pumilio-family RNA binding domain

  19. XM_030253926.2 → XP_030109786.1  pumilio homolog 1 isoform X20

    UniProtKB/TrEMBL
    Q3UR00
    Conserved Domains (1) summary
    cd07920
    Location:748 → 1069
    Pumilio; Pumilio-family RNA binding domain

  20. XM_036164568.1 → XP_036020461.1  pumilio homolog 1 isoform X29

    UniProtKB/TrEMBL
    Q3TRI4
    Conserved Domains (1) summary
    cd07920
    Location:669 → 992
    Pumilio; Pumilio-family RNA binding domain

  21. XM_036164569.1 → XP_036020462.1  pumilio homolog 1 isoform X30

    UniProtKB/TrEMBL
    Q3TRI4
    Conserved Domains (1) summary
    cd07920
    Location:668 → 989
    Pumilio; Pumilio-family RNA binding domain

  22. XM_030253928.2 → XP_030109788.1  pumilio homolog 1 isoform X26

    UniProtKB/TrEMBL
    Q3UR00
    Conserved Domains (1) summary
    cd07920
    Location:713 → 1036
    Pumilio; Pumilio-family RNA binding domain

  23. XM_006539308.4 → XP_006539371.1  pumilio homolog 1 isoform X36

    See identical proteins and their annotated locations for XP_006539371.1

    UniProtKB/TrEMBL
    Q3UHW0
    Conserved Domains (1) summary
    cd07920
    Location:606 → 929
    Pumilio; Pumilio-family RNA binding domain

  24. XM_036164573.1 → XP_036020466.1  pumilio homolog 1 isoform X37

    UniProtKB/TrEMBL
    Q3UHW0
    Conserved Domains (1) summary
    cd07920
    Location:606 → 927
    Pumilio; Pumilio-family RNA binding domain

  25. XM_006539309.4 → XP_006539372.1  pumilio homolog 1 isoform X38

    See identical proteins and their annotated locations for XP_006539372.1

    UniProtKB/TrEMBL
    Q3UHW0
    Conserved Domains (1) summary
    cd07920
    Location:602 → 925
    Pumilio; Pumilio-family RNA binding domain

  26. XM_006539300.5 → XP_006539363.1  pumilio homolog 1 isoform X22

    See identical proteins and their annotated locations for XP_006539363.1

    UniProtKB/TrEMBL
    Q3U4T5
    Conserved Domains (1) summary
    cd07920
    Location:728 → 1051
    Pumilio; Pumilio-family RNA binding domain

  27. XM_030253927.2 → XP_030109787.1  pumilio homolog 1 isoform X24

    UniProtKB/TrEMBL
    Q3U4T5
    Conserved Domains (1) summary
    cd07920
    Location:724 → 1047
    Pumilio; Pumilio-family RNA binding domain

  28. XM_036164567.1 → XP_036020460.1  pumilio homolog 1 isoform X27

    UniProtKB/TrEMBL
    Q3U4T5
    Conserved Domains (1) summary
    cd07920
    Location:724 → 1045
    Pumilio; Pumilio-family RNA binding domain

  29. XM_030253930.2 → XP_030109790.1  pumilio homolog 1 isoform X25

    UniProtKB/TrEMBL
    Q3U4T5
    Conserved Domains (1) summary
    cd07920
    Location:723 → 1046
    Pumilio; Pumilio-family RNA binding domain

  30. XM_036164572.1 → XP_036020465.1  pumilio homolog 1 isoform X35

    UniProtKB/TrEMBL
    Q3U4T5
    Conserved Domains (1) summary
    cd07920
    Location:644 → 967
    Pumilio; Pumilio-family RNA binding domain

  31. XM_006539301.5 → XP_006539364.1  pumilio homolog 1 isoform X23

    See identical proteins and their annotated locations for XP_006539364.1

    UniProtKB/TrEMBL
    Q3U4T5
    Conserved Domains (1) summary
    cd07920
    Location:727 → 1050
    Pumilio; Pumilio-family RNA binding domain

  32. XM_036164571.1 → XP_036020464.1  pumilio homolog 1 isoform X34

    UniProtKB/TrEMBL
    Q3U4T5
    Conserved Domains (1) summary
    cd07920
    Location:627 → 950
    Pumilio; Pumilio-family RNA binding domain

  33. XM_006539314.5 → XP_006539377.1  pumilio homolog 1 isoform X39

    See identical proteins and their annotated locations for XP_006539377.1

    UniProtKB/TrEMBL
    Q3UHW0
    Conserved Domains (1) summary
    cd07920
    Location:486 → 809
    Pumilio; Pumilio-family RNA binding domain

  34. XM_036164574.1 → XP_036020467.1  pumilio homolog 1 isoform X40

    UniProtKB/TrEMBL
    Q3UHW0
    Conserved Domains (1) summary
    cd07920
    Location:481 → 804
    Pumilio; Pumilio-family RNA binding domain

  35. XM_006539292.4 → XP_006539355.1  pumilio homolog 1 isoform X1

    See identical proteins and their annotated locations for XP_006539355.1

    UniProtKB/TrEMBL
    Q3UR00
    Conserved Domains (1) summary
    cd07920
    Location:848 → 1171
    Pumilio; Pumilio-family RNA binding domain

  36. XM_036164561.1 → XP_036020454.1  pumilio homolog 1 isoform X4

    UniProtKB/Swiss-Prot
    Q80U78, Q80X96, Q80YU8, Q8BPV7, Q9EPU6
    UniProtKB/TrEMBL
    Q3UR00
    Conserved Domains (1) summary
    cd07920
    Location:844 → 1167
    Pumilio; Pumilio-family RNA binding domain

  37. XM_017320461.3 → XP_017175950.1  pumilio homolog 1 isoform X13

    UniProtKB/TrEMBL
    Q3TRI4
    Conserved Domains (1) summary
    cd07920
    Location:764 → 1087
    Pumilio; Pumilio-family RNA binding domain

  38. XM_017320463.2 → XP_017175952.1  pumilio homolog 1 isoform X16

    UniProtKB/TrEMBL
    Q3TRI4
    Conserved Domains (1) summary
    cd07920
    Location:764 → 1085
    Pumilio; Pumilio-family RNA binding domain

  39. XM_017320460.3 → XP_017175949.1  pumilio homolog 1 isoform X12

    UniProtKB/TrEMBL
    Q3TRI4
    Conserved Domains (1) summary
    cd07920
    Location:765 → 1088
    Pumilio; Pumilio-family RNA binding domain

  40. XM_017320462.3 → XP_017175951.1  pumilio homolog 1 isoform X14

    UniProtKB/TrEMBL
    Q3TRI4
    Conserved Domains (1) summary
    cd07920
    Location:765 → 1086
    Pumilio; Pumilio-family RNA binding domain

  41. XM_036164566.1 → XP_036020459.1  pumilio homolog 1 isoform X24

    UniProtKB/TrEMBL
    Q3U4T5
    Conserved Domains (1) summary
    cd07920
    Location:724 → 1047
    Pumilio; Pumilio-family RNA binding domain

  42. XM_036164570.1 → XP_036020463.1  pumilio homolog 1 isoform X33

    UniProtKB/TrEMBL
    Q3U4T5
    Conserved Domains (1) summary
    cd07920
    Location:632 → 955
    Pumilio; Pumilio-family RNA binding domain
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q80U78.2 GenPept UniProtKB/Swiss-Prot:Q80U78

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