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OR4A16 olfactory receptor family 4 subfamily A member 16 [ Homo sapiens (human) ]

Gene ID: 81327, updated on 11-Apr-2024

Summary

Official Symbol
OR4A16provided by HGNC
Official Full Name
olfactory receptor family 4 subfamily A member 16provided by HGNC
Primary source
HGNC:HGNC:15153
See related
Ensembl:ENSG00000181961 AllianceGenome:HGNC:15153
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OR4A16Q; OR11-117
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Orthologs
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Genomic context

Location:
11q11
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (55343201..55344187)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (55281439..55282425)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (55110677..55111663)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 4 subfamily A member 11 pseudogene Neighboring gene olfactory receptor family 4 subfamily A member 12 pseudogene Neighboring gene olfactory receptor family 4 subfamily A member 15 Neighboring gene olfactory receptor family 4 subfamily A member 9 pseudogene

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
olfactory receptor 4A16
Names
olfactory receptor OR11-117

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001005274.1NP_001005274.1  olfactory receptor 4A16

    See identical proteins and their annotated locations for NP_001005274.1

    Status: VALIDATED

    Source sequence(s)
    AB065519
    Consensus CDS
    CCDS31499.1
    UniProtKB/Swiss-Prot
    Q6IFL3, Q8NH70
    UniProtKB/TrEMBL
    A0A126GW87, B9EIN3
    Related
    ENSP00000325128.2, ENST00000314721.5
    Conserved Domains (2) summary
    pfam00001
    Location:39285
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:29303
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    55343201..55344187
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    55281439..55282425
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)