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AKR2B ankyrin repeat-containing 2B [ Arabidopsis thaliana (thale cress) ]

Gene ID: 816246, updated on 18-Sep-2024

Summary

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Official Symbol
AKR2B
Official Full Name
ankyrin repeat-containing 2B
Primary source
TAIR:AT2G17390
Locus tag
AT2G17390
See related
Araport:AT2G17390
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ankyrin repeat-containing 2B; F5J6.15; F5J6_15
Summary
Highly homologous to AKR2A. Involved in chloroplast biogenesis. Double mutants of AKR2A and AKR2B have yellow leaves, significantly reduced chloroplast proteins, and no thylakoid membranes.
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Genomic context

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See AKR2B in Genome Data Viewer
Location:
chromosome: 2
Exon count:
9
Sequence:
Chromosome: 2; NC_003071.7 (7555586..7558064)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene 3-hydroxy-3-methylglutaryl-CoA reductase 2 Neighboring gene associated protein 19 Neighboring gene ARID/BRIGHT DNA-binding domain-containing protein Neighboring gene NADPH-dependent thioredoxin reductase A

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A calmodulin-binding/CGCG box DNA-binding protein family involved in multiple signaling pathways in plants. Yang T, et al. J Biol Chem, 2002 Nov 22. PMID 12218065
  2. ANKYRIN REPEAT-CONTAINING PROTEIN 2A is an essential molecular chaperone for peroxisomal membrane-bound ASCORBATE PEROXIDASE3 in Arabidopsis. Shen G, et al. Plant Cell, 2010 Mar. PMID 20215589, Free PMC Article
  3. Isolation and identification of ubiquitin-related proteins from Arabidopsis seedlings. Igawa T, et al. J Exp Bot, 2009. PMID 19429840, Free PMC Article
  4. Mapping the signaling network of BIN2 kinase using TurboID-mediated biotin labeling and phosphoproteomics. Kim TW, et al. Plant Cell, 2023 Mar 15. PMID 36660928, Free PMC Article
  5. A proteomic strategy for global analysis of plant protein complexes. Aryal UK, et al. Plant Cell, 2014 Oct. PMID 25293756, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_127294.5

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within regulation of DNA-templated transcription TAS
Traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol HDA PubMed 
located_in mitochondrion HDA PubMed 
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
ankyrin repeat-containing 2B
NP_179331.1
  • ankyrin repeat-containing 2B (AKR2B); FUNCTIONS IN: transcription regulator activity; LOCATED IN: plasma membrane; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Ankyrin repeat-containing domain (InterPro:IPR020683), Ankyrin repeat (InterPro:IPR002110); BEST Arabidopsis thaliana protein match is: ankyrin repeat-containing protein 2 (TAIR:AT4G35450.1); Has 80350 Blast hits to 27630 proteins in 1286 species: Archae - 139; Bacteria - 6360; Metazoa - 42384; Fungi - 5488; Plants - 3518; Viruses - 784; Other Eukaryotes - 21677 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    7555586..7558064
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_127294.5 → NP_179331.1  ankyrin repeat-containing 2B [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_179331.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q29Q26
    UniProtKB/TrEMBL
    A0A5S9WYY9, A0A654EYN8
    Conserved Domains (3) summary
    sd00045
    Location:252 → 283
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:225 → 316
    Ank_2; Ankyrin repeats (3 copies)
    cl17974
    Location:155 → 198
    STI1; STI1 domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q29Q26.1

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