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COV1 CONTINUOUS VASCULAR RING protein (DUF502) [ Arabidopsis thaliana (thale cress) ]

Gene ID: 816531, updated on 18-Sep-2024

Summary

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Official Symbol
COV1
Official Full Name
CONTINUOUS VASCULAR RING protein (DUF502)
Primary source
TAIR:AT2G20120
Locus tag
AT2G20120
See related
Araport:AT2G20120
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
CONTINUOUS VASCULAR RING; T2G17.8; T2G17_8
Summary
Encodes an integral membrane protein of unknown function, highly conserved between plants and bacteria; is likely to be involved in a mechanism that negatively regulates the differentiation of vascular tissue in the stem. Mutants display a dramatic increase in vascular tissue development in the stem in place of the interfascicular region that normally separates the vascular bundles.
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Genomic context

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See COV1 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
8
Sequence:
Chromosome: 2; NC_003071.7 (8687330..8690214, complement)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene basic helix-loop-helix (bHLH) DNA-binding superfamily protein Neighboring gene Tesmin/TSO1-like CXC domain-containing protein Neighboring gene uncharacterized protein Neighboring gene AAA-type ATPase family protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. CONTINUOUS VASCULAR RING (COV1) is a trans-Golgi network-localized membrane protein required for Golgi morphology and vacuolar protein sorting. Shirakawa M, et al. Plant Cell Physiol, 2014 Apr. PMID 24363287
  2. Isolation of COV1, a gene involved in the regulation of vascular patterning in the stem of Arabidopsis. Parker G, et al. Development, 2003 May. PMID 12668628
  3. Isolation and proteomic characterization of the Arabidopsis Golgi defines functional and novel components involved in plant cell wall biosynthesis. Parsons HT, et al. Plant Physiol, 2012 May. PMID 22430844, Free PMC Article
  4. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. the novel tans Golgi network-localized protein COV1 is required for Golgi morphology, vacuolar trafficking and myrosin cell development.
    Title: CONTINUOUS VASCULAR RING (COV1) is a trans-Golgi network-localized membrane protein required for Golgi morphology and vacuolar protein sorting.
Submit: New GeneRIF Correction

General gene information

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Homology

NM_001335662.1
NM_127570.5

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
NOT involved_in auxin-activated signaling pathway IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within stem vascular tissue pattern formation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus HDA PubMed 
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
CONTINUOUS VASCULAR RING protein (DUF502)
NP_565464.2
  • CONTINUOUS VASCULAR RING (COV1); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: stem vascular tissue pattern formation; LOCATED IN: integral to membrane; EXPRESSED IN: stem, root, flower, leaf; CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF502 (InterPro:IPR007462); BEST Arabidopsis thaliana protein match is: like COV 1 (TAIR:AT2G20130.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    8687330..8690214 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_127570.5 → NP_565464.2  CONTINUOUS VASCULAR RING protein (DUF502) [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_565464.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A0A1P8AZ44, F4IUE7, Q0WL91, Q94EH1, Q9SL69
    UniProtKB/TrEMBL
    A0A178VYU8, A0A5S9WZG8
    Conserved Domains (1) summary
    pfam04367
    Location:112 → 213
    DUF502; Protein of unknown function (DUF502)

  2. NM_001335662.1 → NP_001324133.1  CONTINUOUS VASCULAR RING protein (DUF502) [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A0A1P8AZ44, F4IUE7, Q0WL91, Q94EH1, Q9SL69
    UniProtKB/TrEMBL
    A0A178VYU8, A0A5S9WZG8
Nucleotide Protein
Heading Accession and Version

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