DBP1 DNA-binding protein phosphatase 1 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: DBP1
Official Full Name: DNA-binding protein phosphatase 1
Primary source: TAIR:AT2G25620
Locus tag: AT2G25620
See related: Araport:AT2G25620
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: AtDBP1; DNA-binding protein phosphatase 1
Summary: Encodes DBP1, a member of the DBP factors (DNA-binding protein phosphatases) featuring sequence-specific DNA-binding and protein phosphatase activity. DBP1 is involved in plant-potyvirus interactions. Loss-of-function of DBP1 renders resistance to potyviruses.
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Genomic context

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See DBP1 in Genome Data Viewer

Location:: chromosome: 2

Exon count:: 4

Sequence:: Chromosome: 2; NC_003071.7 (10902716..10905287, complement)

Chromosome 2 - NC_003071.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phosphatase AtDBP1 negatively regulates drought and salt tolerance through altering leaf surface permeability in Arabidopsis.
Title: Phosphatase AtDBP1 negatively regulates drought and salt tolerance through altering leaf surface permeability in Arabidopsis.
AtDBP1 plays an effective role for flowering time regulation and report a novel function of DBP factors in planta besides in plant defense.
Title: DNA-binding protein phosphatase AtDBP1 acts as a promoter of flowering in Arabidopsis.
The tissue expression pattern of this gene was evaluated.
Title: Functional analysis of an auxin-inducible DNA-binding protein gene.
MPK11 interacts with GRF6 and is negatively modulated by DBP1.
Title: Arabidopsis protein phosphatase DBP1 nucleates a protein network with a role in regulating plant defense.
The ATdbp1 mutant showed enhanced resistance to infection by two potyviruses. AtDBP1 interacts with and stabilizes eIF(iso)4E. [DBP1]
Title: DNA-binding protein phosphatase AtDBP1 mediates susceptibility to two potyviruses in Arabidopsis.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_128120.2

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables myosin phosphatase activity	IEA Inferred from Electronic Annotation more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within regulation of defense response to virus	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in cytosol	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info

General protein information

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Preferred Names: DNA-binding protein phosphatase 1

NP_180133.1

DNA-binding protein phosphatase 1 (DBP1); FUNCTIONS IN: protein serine/threonine phosphatase activity, catalytic activity; INVOLVED IN: regulation of defense response to virus; LOCATED IN: protein serine/threonine phosphatase complex; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Protein phosphatase 2C, manganese/magnesium aspartate binding site (InterPro:IPR000222), Protein phosphatase 2C-related (InterPro:IPR001932), Protein phosphatase 2C (InterPro:IPR015655), Protein phosphatase 2C, N-terminal (InterPro:IPR014045); BEST Arabidopsis thaliana protein match is: Protein phosphatase 2C family protein (TAIR:AT2G33700.1); Has 7196 Blast hits to 7030 proteins in 671 species: Archae - 12; Bacteria - 774; Metazoa - 1729; Fungi - 719; Plants - 2627; Viruses - 7; Other Eukaryotes - 1328 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003071.7 Reference assembly

Range

10902716..10905287 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001336005.1 → NP_001324148.1 DNA-binding protein phosphatase 1 [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/Swiss-Prot

Q9SLA1

UniProtKB/TrEMBL

A0A178VZ04, A0A5S9X1B1

Conserved Domains (1) summary

PLN03145
Location:3 → 392

PLN03145; Protein phosphatase 2c; Provisional
NM_128120.2 → NP_180133.1 DNA-binding protein phosphatase 1 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_180133.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q9SLA1

UniProtKB/TrEMBL

A0A178VZ04, A0A5S9X1B1

Conserved Domains (1) summary

PLN03145
Location:3 → 392

PLN03145; Protein phosphatase 2c; Provisional