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Excinuclease ABC, C subunit, N-terminal [ Arabidopsis thaliana (thale cress) ]

Gene ID: 817585, updated on 18-Sep-2024

Summary

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Official Full Name
Excinuclease ABC, C subunit, N-terminal
Primary source
TAIR:AT2G30350
Locus tag
AT2G30350
See related
Araport:AT2G30350
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
T9D9.16; T9D9_16
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Genomic context

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Location:
chromosome: 2
Exon count:
4
Sequence:
Chromosome: 2; NC_003071.7 (12934149..12935784, complement)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene GCN5L1 family protein Neighboring gene LOB domain-containing protein 13 Neighboring gene ncRNA Neighboring gene SOS3-interacting protein 4 Neighboring gene allergen-like protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Holliday junction resolution by At-HIGLE: an SLX1 lineage endonuclease from Arabidopsis thaliana with a novel in-built regulatory mechanism. Verma P, et al. Nucleic Acids Res, 2022 May 6. PMID 35412622, Free PMC Article
  2. HIGLE is a bifunctional homing endonuclease that directly interacts with HYL1 and SERRATE in Arabidopsis thaliana. Cho SK, et al. FEBS Lett, 2017 May. PMID 28321834
  3. Arabidopsis MAS2, an Essential Gene That Encodes a Homolog of Animal NF-κ B Activating Protein, Is Involved in 45S Ribosomal DNA Silencing. Sánchez-García AB, et al. Plant Cell, 2015 Jul. PMID 26139346, Free PMC Article
  4. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Holliday junction resolution by At-HIGLE: an SLX1 lineage endonuclease from Arabidopsis thaliana with a novel in-built regulatory mechanism.
    Title: Holliday junction resolution by At-HIGLE: an SLX1 lineage endonuclease from Arabidopsis thaliana with a novel in-built regulatory mechanism.
  2. Results show the involvement of a novel gene, HYL1-interacting GIY-YIG-like endonuclease (HIGLE). The encoded protein has a GIY-YIG domain that is generally found within a class of homing endonucleases. HIGLE directly interacts with HYL1 and SE. Unlike the functions of other GIY-YIG endonucleases, the catalytic core of HIGLE has both DNase and RNase activities.[HIGLE]
    Title: HIGLE is a bifunctional homing endonuclease that directly interacts with HYL1 and SERRATE in Arabidopsis thaliana.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_128588.5
NM_179811.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables 5'-flap endonuclease activity IEA
Inferred from Electronic Annotation
more info
  
enables DNA endonuclease activity, producing 3'-phosphomonoesters IDA
Inferred from Direct Assay
more info
 PubMed 
enables RNA endonuclease activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables crossover junction DNA endonuclease activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in pre-miRNA 3'-end processing IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
part_of microprocessor complex IPI
Inferred from Physical Interaction
more info
 PubMed 
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
Excinuclease ABC, C subunit, N-terminal
NP_180594.2
  • Excinuclease ABC, C subunit, N-terminal; FUNCTIONS IN: nuclease activity; INVOLVED IN: DNA repair; LOCATED IN: intracellular; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Excinuclease ABC, C subunit, N-terminal (InterPro:IPR000305); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
NP_850142.2
  • Excinuclease ABC, C subunit, N-terminal; Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    12934149..12935784 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_128588.5 → NP_180594.2  Excinuclease ABC, C subunit, N-terminal [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_180594.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178VUD7, A0A654EYX9, Q682H4
    Conserved Domains (1) summary
    cd10455
    Location:27 → 101
    GIY-YIG_SLX1; Catalytic GIY-YIG domain of yeast structure-specific endonuclease subunit SLX1 and its eukaryotic homologs

  2. NM_179811.3 → NP_850142.2  Excinuclease ABC, C subunit, N-terminal [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_850142.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    F4IMS7
    Conserved Domains (1) summary
    cl15257
    Location:58 → 67
    GIY-YIG_SF; GIY-YIG nuclease domain superfamily
Nucleotide Protein
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