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ADS2 16:0delta9 desaturase 2 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 817694, updated on 18-Sep-2024

Summary

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Official Symbol
ADS2
Official Full Name
16:0delta9 desaturase 2
Primary source
TAIR:AT2G31360
Locus tag
AT2G31360
See related
Araport:AT2G31360
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
16:0delta9 desaturase 2; AtADS2; DELTA 9 DESATURASE; T28P16.15; T28P16_15
Summary
Encodes a protein homologous to delta 9 acyl-lipid desaturases of cyanobacteria and acyl-CoA desaturases of yeast and mammals. expression up-regulated by cold temperature. It is involved in the synthesis of the 24:1n-9 and 26:1n-9 components of seed lipids, sphingolipids and the membrane phospholipids phosphatidylserine (PS), and phosphatidylethanolamine (PE).
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Genomic context

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See ADS2 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
6
Sequence:
Chromosome: 2; NC_003071.7 (13371658..13374018, complement)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene embryo defective 1381 Neighboring gene uncharacterized protein Neighboring gene glyoxalase 2-5 Neighboring gene Basic-leucine zipper (bZIP) transcription factor family protein Neighboring gene pfkB-like carbohydrate kinase family protein Neighboring gene salt tolerance homologue

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. ACYL-LIPID DESATURASE2 is required for chilling and freezing tolerance in Arabidopsis. Chen M, et al. Plant Cell, 2013 Apr. PMID 23585650, Free PMC Article
  2. Involvement of Arabidopsis ACYL-COENZYME A DESATURASE-LIKE2 (At2g31360) in the biosynthesis of the very-long-chain monounsaturated fatty acid components of membrane lipids. Smith MA, et al. Plant Physiol, 2013 Jan. PMID 23175755, Free PMC Article
  3. Integrative analysis of transcript and metabolite profiling data sets to evaluate the regulation of biochemical pathways during photomorphogenesis. Ghassemian M, et al. Arch Biochem Biophys, 2006 Apr 15. PMID 16460663
  4. Arabidopsis G-protein interactome reveals connections to cell wall carbohydrates and morphogenesis. Klopffleisch K, et al. Mol Syst Biol, 2011 Sep 27. PMID 21952135, Free PMC Article
  5. Putative glycosyltransferases and other plant Golgi apparatus proteins are revealed by LOPIT proteomics. Nikolovski N, et al. Plant Physiol, 2012 Oct. PMID 22923678, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Data indicate that ADS2 is essential to adjust the acyl composition of organelle membrane lipid composition in response to cold stress.
    Title: ACYL-LIPID DESATURASE2 is required for chilling and freezing tolerance in Arabidopsis.
  2. AtADS2 is involved in the synthesis of glycerolipid and sphingolipids in the seed.
    Title: Involvement of Arabidopsis ACYL-COENZYME A DESATURASE-LIKE2 (At2g31360) in the biosynthesis of the very-long-chain monounsaturated fatty acid components of membrane lipids.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_128693.5

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in response to red light IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in unsaturated fatty acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within very long-chain fatty acid biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum HDA PubMed 
located_in endoplasmic reticulum membrane IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
16:0delta9 desaturase 2
NP_565721.1
  • 16:0delta9 desaturase 2 (DS2); FUNCTIONS IN: oxidoreductase activity, oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water; INVOLVED IN: oxidation reduction, lipid metabolic process; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Fatty acid desaturase, type 1, core (InterPro:IPR015876), Fatty acid desaturase, type 1 (InterPro:IPR005804); BEST Arabidopsis thaliana protein match is: delta 9 desaturase 1 (TAIR:AT1G06080.1); Has 3454 Blast hits to 3454 proteins in 832 species: Archae - 0; Bacteria - 1553; Metazoa - 797; Fungi - 236; Plants - 106; Viruses - 4; Other Eukaryotes - 758 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    13371658..13374018 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001336328.1 → NP_001323798.1  16:0delta9 desaturase 2 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O65798, Q8LD80, Q9SID2
    UniProtKB/TrEMBL
    A0A178VRL6, A0A5S9X310
    Conserved Domains (1) summary
    PLN02220
    Location:1 → 307
    PLN02220; delta-9 acyl-lipid desaturase

  2. NM_128693.5 → NP_565721.1  16:0delta9 desaturase 2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_565721.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O65798, Q8LD80, Q9SID2
    UniProtKB/TrEMBL
    A0A178VRL6, A0A5S9X310
    Conserved Domains (1) summary
    PLN02220
    Location:1 → 307
    PLN02220; delta-9 acyl-lipid desaturase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9SID2.2

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