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LAC5 laccase 5 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 818630, updated on 18-Sep-2024

Summary

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Official Symbol
LAC5
Official Full Name
laccase 5
Primary source
TAIR:AT2G40370
Locus tag
AT2G40370
See related
Araport:AT2G40370
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
laccase 5; T3G21.14; T3G21_14
Summary
putative laccase, a member of laccase family of genes (17 members in Arabidopsis).
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Genomic context

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See LAC5 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
6
Sequence:
Chromosome: 2; NC_003071.7 (16857959..16860779, complement)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Integrase-type DNA-binding superfamily protein Neighboring gene Transducin/WD40 repeat-like superfamily protein Neighboring gene prenylated RAB acceptor 1.B2 Neighboring gene neuronal PAS domain protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. High-order mutants reveal an essential requirement for peroxidases but not laccases in Casparian strip lignification. Rojas-Murcia N, et al. Proc Natl Acad Sci U S A, 2020 Nov 17. PMID 33139576, Free PMC Article
  2. MicroRNA-mediated systemic down-regulation of copper protein expression in response to low copper availability in Arabidopsis. Abdel-Ghany SE, et al. J Biol Chem, 2008 Jun 6. PMID 18408011, Free PMC Article
  3. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

GeneRIFs: Gene References Into Functions

General gene information

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Markers

NM_129597.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables copper ion binding IEA
Inferred from Electronic Annotation
more info
  
enables hydroquinone:oxygen oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within response to copper ion IEP
Inferred from Expression Pattern
more info
 PubMed 
Component Evidence Code Pubs
located_in Casparian strip IDA
Inferred from Direct Assay
more info
 PubMed 
located_in extracellular region ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
laccase 5
NP_181568.1
  • laccase 5 (LAC5); FUNCTIONS IN: laccase activity; INVOLVED IN: response to copper ion; LOCATED IN: endomembrane system, apoplast; EXPRESSED IN: 8 plant structures; EXPRESSED DURING: 4 anthesis, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Multicopper oxidase, type 3 (InterPro:IPR011707), Laccase (InterPro:IPR017761), Multicopper oxidase, type 2 (InterPro:IPR011706), Cupredoxin (InterPro:IPR008972), Multicopper oxidase, copper-binding site (InterPro:IPR002355), Multicopper oxidase, type 1 (InterPro:IPR001117); BEST Arabidopsis thaliana protein match is: laccase 12 (TAIR:AT5G05390.1); Has 10120 Blast hits to 8186 proteins in 1337 species: Archae - 37; Bacteria - 4008; Metazoa - 431; Fungi - 3685; Plants - 1575; Viruses - 0; Other Eukaryotes - 384 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    16857959..16860779 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_129597.4 → NP_181568.1  laccase 5 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_181568.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9SIY8
    UniProtKB/TrEMBL
    A0A178VWJ4, A0A5S9X5R1
    Conserved Domains (4) summary
    cd13849
    Location:31 → 147
    CuRO_1_LCC_plant; The first cupredoxin domain of plant laccases
    cd13875
    Location:162 → 309
    CuRO_2_LCC_plant; The second cupredoxin domain of the plant laccases
    cd13897
    Location:424 → 563
    CuRO_3_LCC_plant; The third cupredoxin domain of the plant laccases
    TIGR03389
    Location:27 → 580
    laccase; laccase, plant
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9SIY8.1

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