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HAM1 GRAS family transcription factor [ Arabidopsis thaliana (thale cress) ]

Gene ID: 819124, updated on 18-Sep-2024

Summary

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Official Symbol
HAM1
Official Full Name
GRAS family transcription factor
Primary source
TAIR:AT2G45160
Locus tag
AT2G45160
See related
Araport:AT2G45160
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ARABIDOPSIS THALIANA HAIRY MERISTEM 1; ATHAM1; HAIRY MERISTEM 1; LOM1; LOST MERISTEMS 1; SCARECROW-LIKE 27; SCL27; T14P1.3
Summary
Belongs to one of the LOM (LOST MERISTEMS) genes: AT2G45160 (LOM1), AT3G60630 (LOM2) and AT4G00150 (LOM3). LOM1 and LOM2 promote cell differentiation at the periphery of shoot meristems and help to maintain their polar organization.
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Genomic context

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See HAM1 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
1
Sequence:
Chromosome: 2; NC_003071.7 (18617862..18620451, complement)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene plant VAP homolog 12 Neighboring gene cytidinediphosphate diacylglycerol synthase 4 Neighboring gene AUTOPHAGY 8E Neighboring gene Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. miRNAs control HAM1 functions at the single-cell-layer level and are essential for normal embryogenesis in Arabidopsis. Takanashi H, et al. Plant Mol Biol, 2018 Apr. PMID 29574557
  2. LOST MERISTEMS genes regulate cell differentiation of central zone descendants in Arabidopsis shoot meristems. Schulze S, et al. Plant J, 2010 Nov. PMID 21070418
  3. Arabidopsis homologs of the petunia hairy meristem gene are required for maintenance of shoot and root indeterminacy. Engstrom EM, et al. Plant Physiol, 2011 Feb. PMID 21173022, Free PMC Article
  4. Arabidopsis miR171-targeted scarecrow-like proteins bind to GT cis-elements and mediate gibberellin-regulated chlorophyll biosynthesis under light conditions. Ma Z, et al. PLoS Genet, 2014 Aug. PMID 25101599, Free PMC Article
  5. Control of plant stem cell function by conserved interacting transcriptional regulators. Zhou Y, et al. Nature, 2015 Jan 15. PMID 25363783, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Results indicate that the control of HAIRY MERISTEM 1 (HAM1) functions at the single-cell-layer level by miR171a is essential for proper organ formation.
    Title: miRNAs control HAM1 functions at the single-cell-layer level and are essential for normal embryogenesis in Arabidopsis.
  2. AtHAM1, AtHAM2, and AtHAM3 are expressed in apical meristems and in differentiating and mature tissues of both shoot and root.
    Title: Arabidopsis homologs of the petunia hairy meristem gene are required for maintenance of shoot and root indeterminacy.
  3. findings show that LOM1(AT2G45160) and LOM2 (AT3G60630) promote cell differentiation at the periphery of shoot meristems and help to maintain their polar organization
    Title: LOST MERISTEMS genes regulate cell differentiation of central zone descendants in Arabidopsis shoot meristems.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_130079.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables DNA-binding transcription factor activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables transcription cis-regulatory region binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within cell differentiation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within cell division IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within regulation of DNA-templated transcription TAS
Traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within root hair cell tip growth IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
GRAS family transcription factor
NP_182041.1
  • HAIRY MERISTEM 1 (HAM1); CONTAINS InterPro DOMAIN/s: Transcription factor GRAS (InterPro:IPR005202); BEST Arabidopsis thaliana protein match is: GRAS family transcription factor (TAIR:AT3G60630.1); Has 2292 Blast hits to 2267 proteins in 299 species: Archae - 0; Bacteria - 2; Metazoa - 4; Fungi - 0; Plants - 2284; Viruses - 0; Other Eukaryotes - 2 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    18617862..18620451 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_130079.3 → NP_182041.1  GRAS family transcription factor [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_182041.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q7XJM8, Q84WB1
    UniProtKB/TrEMBL
    A0A178VMD3, A0A384KUR0, B7ZWR8
    Conserved Domains (1) summary
    pfam03514
    Location:268 → 639
    GRAS; GRAS domain family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7XJM8.1

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