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WRKY23 WRKY DNA-binding protein 23 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 819339, updated on 18-Sep-2024

Summary

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Official Symbol
WRKY23
Official Full Name
WRKY DNA-binding protein 23
Primary source
TAIR:AT2G47260
Locus tag
AT2G47260
See related
Araport:AT2G47260
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATWRKY23; T8I13.10; WRKY DNA-binding protein 23; WRKY DNA-BINDING PROTEIN 23
Summary
Encodes a member of WRKY Transcription Factor; Group I. Involved in nematode feeding site establishment.
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Genomic context

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See WRKY23 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
3
Sequence:
Chromosome: 2; NC_003071.7 (19404802..19407098, complement)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene long chain acyl-CoA synthetase Neighboring gene RNA helicase family protein Neighboring gene transcription factor UPBEAT protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. WRKY23 is a component of the transcriptional network mediating auxin feedback on PIN polarity. Prát T, et al. PLoS Genet, 2018 Jan. PMID 29377885, Free PMC Article
  2. Tightly controlled WRKY23 expression mediates Arabidopsis embryo development. Grunewald W, et al. EMBO Rep, 2013 Dec. PMID 24157946, Free PMC Article
  3. Transcription factor WRKY23 assists auxin distribution patterns during Arabidopsis root development through local control on flavonol biosynthesis. Grunewald W, et al. Proc Natl Acad Sci U S A, 2012 Jan 31. PMID 22307611, Free PMC Article
  4. A role for AtWRKY23 in feeding site establishment of plant-parasitic nematodes. Grunewald W, et al. Plant Physiol, 2008 Sep. PMID 18599655, Free PMC Article
  5. Transcriptional activation by WRKY23 and derepression by removal of bHLH041 coordinately establish callus pluripotency in Arabidopsis regeneration. Xu C, et al. Plant Cell, 2023 Dec 21. PMID 37804093, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Gain- and loss-of-function mutants confirmed a role for WRKY23 in mediating the auxin effect on the PIN polarity. Accordingly, processes requiring auxin-mediated PIN polarity rearrangements, such as vascular tissue development during leaf venation, showed a higher WRKY23 expression and required the WRKY23 activity.
    Title: WRKY23 is a component of the transcriptional network mediating auxin feedback on PIN polarity.
  2. Knocking down WRKY23 transcript levels or expression of a dominant-negative WRKY23 affected both apical-basal axis formation as well as installation of the root stem cell niche.
    Title: Tightly controlled WRKY23 expression mediates Arabidopsis embryo development.
  3. results suggest a model in which WRKY23 is part of a transcriptional feedback loop of auxin on its own transport through local regulation of flavonol biosynthesis
    Title: Transcription factor WRKY23 assists auxin distribution patterns during Arabidopsis root development through local control on flavonol biosynthesis.
  4. WRKY23 is expressed during the early stages of nematode feeding site establishment.
    Title: A role for AtWRKY23 in feeding site establishment of plant-parasitic nematodes.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_130294.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables DNA-binding transcription factor activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables transcription cis-regulatory region binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in callus formation IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within positive regulation of DNA-templated transcription initiation IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within protein localization involved in auxin polar transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within response to auxin IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in response to auxin IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within response to nematode IEP
Inferred from Expression Pattern
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
WRKY DNA-binding protein 23
NP_182248.1
  • WRKY DNA-binding protein 23 (WRKY23); CONTAINS InterPro DOMAIN/s: DNA-binding WRKY (InterPro:IPR003657), Transcription factor, WRKY group IIc (InterPro:IPR017396); BEST Arabidopsis thaliana protein match is: WRKY family transcription factor (TAIR:AT3G62340.1); Has 3541 Blast hits to 3088 proteins in 202 species: Archae - 0; Bacteria - 3; Metazoa - 11; Fungi - 7; Plants - 3503; Viruses - 0; Other Eukaryotes - 17 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    19404802..19407098 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_130294.4 → NP_182248.1  WRKY DNA-binding protein 23 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O22900
    UniProtKB/TrEMBL
    A0A178VQ40, A0A5S9X7R5, A0A654F2Q1
    Conserved Domains (1) summary
    smart00774
    Location:173 → 230
    WRKY; DNA binding domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O22900.1

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