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WNK6 with no lysine (K) kinase 6 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 821406, updated on 18-Sep-2024

Summary

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Official Symbol
WNK6
Official Full Name
with no lysine (K) kinase 6
Primary source
TAIR:AT3G18750
Locus tag
AT3G18750
See related
Araport:AT3G18750
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ARABIDOPSIS THALIANA WITH NO K 6; ATWNK6; with no lysine (K) kinase 6; ZIK5
Summary
Encodes a member of the WNK family (9 members in all) of protein kinases, the structural design of which is clearly distinct from those of other known protein kinases, such as receptor-like kinases and mitogen-activated protein kinases. Its transcription is under the control of circadian rhythms.
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Genomic context

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See WNK6 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
9
Sequence:
Chromosome: 3; NC_003074.8 (6454013..6457613, complement)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene F-box family protein Neighboring gene tetratricopeptide repeat (TPR)-containing protein Neighboring gene Ribosomal protein L7Ae/L30e/S12e/Gadd45 family protein Neighboring gene Translation elongation factor EF1B/ribosomal protein S6 family protein Neighboring gene Autophagy-related protein 13

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Compilation and characterization of a novel WNK family of protein kinases in Arabiodpsis thaliana with reference to circadian rhythms. Nakamichi N, et al. Biosci Biotechnol Biochem, 2002 Nov. PMID 12506983
  2. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

GeneRIFs: Gene References Into Functions

General gene information

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NM_001035646.2
NM_001202999.2
NM_001338354.1
NM_001338355.1
NM_001338356.1
NM_112761.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein kinase activity TAS
Traceable Author Statement
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within protein phosphorylation TAS
Traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
with no lysine (K) kinase 6
NP_001189928.1
  • with no lysine (K) kinase 6 (WNK6); CONTAINS InterPro DOMAIN/s: Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase domain (InterPro:IPR002290), Tyrosine-protein kinase, catalytic domain (InterPro:IPR020635), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Protein kinase-like domain (InterPro:IPR011009); BEST Arabidopsis thaliana protein match is: Protein kinase superfamily protein (TAIR:AT1G49160.2).
NP_001319584.1
  • with no lysine (K) kinase 6 (WNK6); CONTAINS InterPro DOMAIN/s: Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: Protein kinase superfamily protein (TAIR:AT1G49160.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
NP_188505.1
  • with no lysine (K) kinase 6 (WNK6); CONTAINS InterPro DOMAIN/s: Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase domain (InterPro:IPR002290), Tyrosine-protein kinase, catalytic domain (InterPro:IPR020635), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: Protein kinase superfamily protein (TAIR:AT1G49160.2); Has 109997 Blast hits to 108787 proteins in 3825 species: Archae - 81; Bacteria - 10561; Metazoa - 41131; Fungi - 10681; Plants - 29357; Viruses - 431; Other Eukaryotes - 17755 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    6454013..6457613 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001202999.2 → NP_001189928.1  with no lysine (K) kinase 6 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001189928.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q2V3U7, Q8S8Y8, Q9LSA2
    UniProtKB/TrEMBL
    A0A178V4R3
    Conserved Domains (2) summary
    smart00220
    Location:32 → 285
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd13983
    Location:26 → 285
    STKc_WNK; Catalytic domain of the Serine/Threonine kinase, With No Lysine (WNK) kinase

  2. NM_001338355.1 → NP_001326381.1  with no lysine (K) kinase 6 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178V4R3, A0A1I9LP39

  3. NM_001035646.2 → NP_001030723.1  with no lysine (K) kinase 6 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001030723.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178V4R3
    Conserved Domains (2) summary
    smart00220
    Location:32 → 183
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cl21453
    Location:26 → 218
    PKc_like; Protein Kinases, catalytic domain

  4. NM_001338354.1 → NP_001319584.1  with no lysine (K) kinase 6 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178V4R3

  5. NM_001338356.1 → NP_001326380.1  with no lysine (K) kinase 6 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q2V3U7, Q8S8Y8, Q9LSA2
    UniProtKB/TrEMBL
    A0A178V4R3

  6. NM_112761.3 → NP_188505.1  with no lysine (K) kinase 6 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_188505.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q2V3U7, Q8S8Y8, Q9LSA2
    UniProtKB/TrEMBL
    A0A178V4R3
    Conserved Domains (2) summary
    smart00220
    Location:32 → 285
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd13983
    Location:26 → 285
    STKc_WNK; Catalytic domain of the Serine/Threonine kinase, With No Lysine (WNK) kinase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8S8Y8.1

Gene LinkOut

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