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ETR2 Signal transduction histidine kinase, hybrid-type, ethylene sensor [ Arabidopsis thaliana (thale cress) ]

Gene ID: 821891, updated on 18-Sep-2024

Summary

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Official Symbol
ETR2
Official Full Name
Signal transduction histidine kinase, hybrid-type, ethylene sensor
Primary source
TAIR:AT3G23150
Locus tag
AT3G23150
See related
Araport:AT3G23150
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ethylene response 2
Summary
Involved in ethylene perception in Arabidopsis
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Genomic context

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See ETR2 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
3
Sequence:
Chromosome: 3; NC_003074.8 (8254559..8257888)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene C2H2 and C2HC zinc fingers superfamily protein Neighboring gene ATP binding / aminoacyl-tRNA ligase/ nucleotide binding protein Neighboring gene plant/protein (DUF668) Neighboring gene low-molecular-weight cysteine-rich 42

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Ethylene receptor ETR2 controls trichome branching by regulating microtubule assembly in Arabidopsis thaliana. Plett JM, et al. J Exp Bot, 2009. PMID 19648171, Free PMC Article
  2. Ligand-induced degradation of the ethylene receptor ETR2 through a proteasome-dependent pathway in Arabidopsis. Chen YF, et al. J Biol Chem, 2007 Aug 24. PMID 17595158
  3. ETR2 is an ETR1-like gene involved in ethylene signaling in Arabidopsis. Sakai H, et al. Proc Natl Acad Sci U S A, 1998 May 12. PMID 9576967, Free PMC Article
  4. Ethylene Receptors Signal via a Noncanonical Pathway to Regulate Abscisic Acid Responses. Bakshi A, et al. Plant Physiol, 2018 Jan. PMID 29158332, Free PMC Article
  5. Ethylene Regulates Levels of Ethylene Receptor/CTR1 Signaling Complexes in Arabidopsis thaliana. Shakeel SN, et al. J Biol Chem, 2015 May 8. PMID 25814663, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. ETR1 and ETR2 have both ethylene-dependent and -independent roles in plant cells that affect responses to abscissic acid.
    Title: Ethylene Receptors Signal via a Noncanonical Pathway to Regulate Abscisic Acid Responses.
  2. ETR1, ETR2, and ETHYLENE INSENSITIVE4 (EIN4) have the prominent roles in rapid growth recovery after removal of ethylene whereas ETR1 was the sole isoform that rescued nutations.
    Title: Ethylene receptor ETHYLENE RECEPTOR1 domain requirements for ethylene responses in Arabidopsis seedlings.
  3. ETR2 controls trichome branching by regulating microtubule assembly.
    Title: Ethylene receptor ETR2 controls trichome branching by regulating microtubule assembly in Arabidopsis thaliana.
  4. ETR2 is degraded by a proteasome-dependent pathway in response to ethylene binding
    Title: Ligand-induced degradation of the ethylene receptor ETR2 through a proteasome-dependent pathway in Arabidopsis.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_001338618.1
NM_113216.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables ethylene binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables ethylene receptor activity IEA
Inferred from Electronic Annotation
more info
  
enables phosphorelay sensor kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein histidine kinase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables protein serine/threonine kinase activity TAS
Traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within cellular response to hypoxia HEP PubMed 
acts_upstream_of_or_within negative regulation of ethylene-activated signaling pathway TAS
Traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IDA
Inferred from Direct Assay
more info
 PubMed 
located_in extracellular region ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
Signal transduction histidine kinase, hybrid-type, ethylene sensor
NP_188956.1
  • ethylene response 2 (ETR2); FUNCTIONS IN: ethylene binding, protein histidine kinase activity, receptor activity, glycogen synthase kinase 3 activity; INVOLVED IN: negative regulation of ethylene mediated signaling pathway; LOCATED IN: endomembrane system, endoplasmic reticulum membrane, membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 7 growth stages; CONTAINS InterPro DOMAIN/s: Signal transduction histidine kinase, homodimeric (InterPro:IPR009082), CheY-like (InterPro:IPR011006), Signal transduction histidine kinase, hybrid-type, ethylene sensor (InterPro:IPR014525), Signal transduction response regulator, receiver domain (InterPro:IPR001789), Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain (InterPro:IPR003661), GAF (InterPro:IPR003018); BEST Arabidopsis thaliana protein match is: Signal transduction histidine kinase, hybrid-type, ethylene sensor (TAIR:AT3G04580.2); Has 29902 Blast hits to 25922 proteins in 2098 species: Archae - 92; Bacteria - 25510; Metazoa - 11; Fungi - 1191; Plants - 1553; Viruses - 6; Other Eukaryotes - 1539 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    8254559..8257888
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_113216.3 → NP_188956.1  Signal transduction histidine kinase, hybrid-type, ethylene sensor [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_188956.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O82429, Q0WPQ2, Q9LTD5
    UniProtKB/TrEMBL
    A0A5S9XF35, A0A654F9W5
    Conserved Domains (4) summary
    cd16938
    Location:470 → 612
    HATPase_ETR2_ERS2-EIN4-like; Histidine kinase-like ATPase domain of Arabidopsis thaliana ETR2, ERS2, and EIN4, and related domains
    cd19933
    Location:646 → 762
    REC_ETR-like; phosphoacceptor receiver (REC) domain of plant ethylene receptors ETR1, ETR2, and EIN4, and similar proteins
    pfam00512
    Location:367 → 425
    HisKA; His Kinase A (phospho-acceptor) domain
    pfam01590
    Location:187 → 331
    GAF; GAF domain

  2. NM_001338618.1 → NP_001326955.1  Signal transduction histidine kinase, hybrid-type, ethylene sensor [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1I9LQU7
    Conserved Domains (3) summary
    PRK11466
    Location:344 → 494
    PRK11466; hybrid sensory histidine kinase TorS; Provisional
    cd16938
    Location:470 → 589
    HATPase_ETR2_ERS2-EIN4-like; Histidine kinase-like ATPase domain of Arabidopsis thaliana ETR2, ERS2, and EIN4, and related domains
    pfam01590
    Location:187 → 331
    GAF; GAF domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q0WPQ2.2

Gene LinkOut

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