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GFAT putative glucosamine-fructose-6-phosphate aminotransferase [ Arabidopsis thaliana (thale cress) ]

Gene ID: 821995, updated on 18-Sep-2024

Summary

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Official Symbol
GFAT
Official Full Name
putative glucosamine-fructose-6-phosphate aminotransferase
Primary source
TAIR:AT3G24090
Locus tag
AT3G24090
See related
Araport:AT3G24090
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
L-glutamine D-fructose-6-phosphate amidotransferase
Summary
Encodes a glutamine-fructose-6-phosphate transaminase that likely plays a role in UDP-N-acetylglucosamine biosynthesis.
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Genomic context

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See GFAT in Genome Data Viewer
Location:
chromosome: 3
Exon count:
10
Sequence:
Chromosome: 3; NC_003074.8 (8697685..8701052, complement)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Zinc knuckle (CCHC-type) family protein Neighboring gene KRR1 family protein Neighboring gene Paired amphipathic helix (PAH2) superfamily protein Neighboring gene Uncharacterized protein family SERF Neighboring gene Calcium-binding EF-hand family protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Deficiency of AtGFAT1 activity impairs growth, pollen germination and tolerance to tunicamycin in Arabidopsis. Vu KV, et al. J Exp Bot, 2019 Mar 27. PMID 30775776, Free PMC Article
  2. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

GeneRIFs: Gene References Into Functions

General gene information

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Homology

NM_113314.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables carbohydrate derivative binding IEA
Inferred from Electronic Annotation
more info
  
enables glutamine-fructose-6-phosphate transaminase (isomerizing) activity IDA
Inferred from Direct Assay
more info
  
enables glutamine-fructose-6-phosphate transaminase (isomerizing) activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in UDP-N-acetylglucosamine biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in UDP-N-acetylglucosamine metabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within glucosamine biosynthetic process IDA
Inferred from Direct Assay
more info
  
involved_in glutamine metabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in pollen wall assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in protein N-linked glycosylation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in response to dithiothreitol IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in response to endoplasmic reticulum stress IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in response to endoplasmic reticulum stress IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
putative glucosamine-fructose-6-phosphate aminotransferase
NP_189051.3
  • glutamine-fructose-6-phosphate transaminase (isomerizing)s;sugar binding;transaminases; FUNCTIONS IN: sugar binding, transaminase activity, glutamine-fructose-6-phosphate transaminase (isomerizing) activity; INVOLVED IN: carbohydrate biosynthetic process, carbohydrate metabolic process, metabolic process; LOCATED IN: cytoplasm; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: Glutamine amidotransferase, class-II (InterPro:IPR000583), Sugar isomerase (SIS) (InterPro:IPR001347), Glucosamine-fructose-6-phosphate aminotransferase, isomerising (InterPro:IPR005855), Glutamine amidotransferase, type II (InterPro:IPR017932); Has 19000 Blast hits to 18984 proteins in 2800 species: Archae - 500; Bacteria - 10467; Metazoa - 411; Fungi - 223; Plants - 106; Viruses - 14; Other Eukaryotes - 7279 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    8697685..8701052 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_113314.4 → NP_189051.3  putative glucosamine-fructose-6-phosphate aminotransferase [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_189051.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A0A178V979, Q9LIP9
    UniProtKB/TrEMBL
    A0A384L621
    Conserved Domains (1) summary
    PLN02981
    Location:1 → 677
    PLN02981; glucosamine:fructose-6-phosphate aminotransferase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9LIP9.1

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