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ABI3 AP2/B3-like transcriptional factor family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 822061, updated on 18-Sep-2024

Summary

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Official Symbol
ABI3
Official Full Name
AP2/B3-like transcriptional factor family protein
Primary source
TAIR:AT3G24650
Locus tag
AT3G24650
See related
Araport:AT3G24650
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ABA INSENSITIVE 3; ABSCISIC ACID INSENSITIVE 3; AtABI3; SIS10; SUGAR INSENSITIVE 10
Summary
Homologous to the maize transcription factor Viviparous-1. Full length ABI3 protein binds to the highly conserved RY motif [DNA motif CATGCA(TG)], present in many seed-specific promoters, and the B3 domains of this transcription factor is necessary for the specific interaction with the RY element. Transcriptional activity of ABI3 requires the B3 DNA-binding domain and an activation domain. In addition to the known N-terminal-located activation domain, a second transcription activation domain was found in the B1 region of ABI3. ABI3 is essential for seed maturation. Regulator of the transition between embryo maturation and early seedling development. Putative seed-specific transcriptional activator. ABI3 is a central regulator in ABA signaling and is unstable in vivo. It interacts with and can by polyubiquitinated by AIP2 in vivo. Based on double mutant analyses, ABI3 interacts genetically with both FUS3 and LEC1 and is involved in controlling accumulation of chlorophyll and anthocyanins, sensitivity to abscisic acid, and expression of the members of the 12S storage protein gene family. In addition, both FUS3 and LEC1 regulate positively the abundance of the ABI3 protein in the seed. Alternative splicing of ABI3 is developmentally regulated by SUA (AT3G54230).
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Genomic context

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See ABI3 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
6
Sequence:
Chromosome: 3; NC_003074.8 (8997370..9001185)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene lyase Neighboring gene transmembrane kinase-like 1 Neighboring gene Pectin lyase-like superfamily protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The role of ABI3 and FUS3 loci in Arabidopsis thaliana on phase transition from late embryo development to germination. Nambara E, et al. Dev Biol, 2000 Apr 15. PMID 10753527
  2. Toward the identification and regulation of the Arabidopsis thaliana ABI3 regulon. Mönke G, et al. Nucleic Acids Res, 2012 Sep 1. PMID 22730287, Free PMC Article
  3. N-acylethanolamine (NAE) inhibits growth in Arabidopsis thaliana seedlings via ABI3-dependent and -independent pathways. Cotter MQ, et al. Plant Signal Behav, 2011 May. PMID 21633189, Free PMC Article
  4. ABI3 expression ceases following, but not during, germination of tomato and Arabidopsis seeds. Bassel GW, et al. J Exp Bot, 2006. PMID 16531465
  5. Transactivation of the Brassica napus napin promoter by ABI3 requires interaction of the conserved B2 and B3 domains of ABI3 with different cis-elements: B2 mediates activation through an ABRE, whereas B3 interacts with an RY/G-box. Ezcurra I, et al. Plant J, 2000 Oct. PMID 11029704

See all (52) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. ABSCISIC ACID INSENSITIVE 3 promotes auxin signalling by regulating SHY2 expression to control primary root growth in response to dehydration stress.
    Title: ABSCISIC ACID INSENSITIVE 3 promotes auxin signalling by regulating SHY2 expression to control primary root growth in response to dehydration stress.
  2. The ABI3-ERF1 module mediates ABA-auxin crosstalk to regulate lateral root emergence.
    Title: The ABI3-ERF1 module mediates ABA-auxin crosstalk to regulate lateral root emergence.
  3. ABA-INSENSITIVE 3 with or without FUSCA3 highly up-regulates lipid droplet proteins and activates oil accumulation.
    Title: ABA-INSENSITIVE 3 with or without FUSCA3 highly up-regulates lipid droplet proteins and activates oil accumulation.
  4. AtMYB32 regulates the ABA response by targeting ABI3, ABI4 and ABI5 and the drought response by targeting CBF4 in Arabidopsis.
    Title: AtMYB32 regulates the ABA response by targeting ABI3, ABI4 and ABI5 and the drought response by targeting CBF4 in Arabidopsis.
  5. Direct and indirect targets of the arabidopsis seed transcription factor ABSCISIC ACID INSENSITIVE3.
    Title: Direct and indirect targets of the arabidopsis seed transcription factor ABSCISIC ACID INSENSITIVE3.
  6. ARABIDOPSIS NITRATE REGULATED 1 acts as a negative modulator of seed germination by activating ABI3 expression.
    Title: ARABIDOPSIS NITRATE REGULATED 1 acts as a negative modulator of seed germination by activating ABI3 expression.
  7. data suggest that BES1-mediated regulation of ABI3 is important in the reproductive phase transition of plants.
    Title: ABSCISIC ACID-INSENSITIVE 3 is involved in brassinosteroid-mediated regulation of flowering in plants.
  8. Genetic and epigenetic essentials required for expression of the ABI3 gene, a crucial factor regulating dehydration stress signalling in Arabidopsis thaliana.
    Title: Transcription factor ABI3 auto-activates its own expression during dehydration stress response.
  9. ABI3 mediates dehydration stress signaling in Arabidopsis through regulation of a group of genes that play a role primarily during stress recovery phase.
    Title: ABI3 mediates dehydration stress recovery response in Arabidopsis thaliana by regulating expression of downstream genes.
  10. The abi3-1 dog1-1 double mutant produced green seeds which are highly abscisic acid (ABA) insensitive, phenocopying severe abi3 mutants, indicating that dog1-1 acts as an enhancer of the weak abi3-1 allele and thus revealing a genetic interaction between both genes.
    Title: The Arabidopsis DELAY OF GERMINATION 1 gene affects ABSCISIC ACID INSENSITIVE 5 (ABI5) expression and genetically interacts with ABI3 during Arabidopsis seed development.
Submit: New GeneRIF Correction See all GeneRIFs (29)

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_113376.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables DNA-binding transcription factor activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables DNA-binding transcription factor activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables DNA-binding transcription factor activity TAS
Traceable Author Statement
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within embryo development ending in seed dormancy IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within mitochondria-nucleus signaling pathway IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within plastid organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within positive regulation of DNA-templated transcription IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within regulation of DNA-templated transcription TAS
Traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within response to abscisic acid IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within response to auxin IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
AP2/B3-like transcriptional factor family protein
NP_189108.1
  • ABA INSENSITIVE 3 (ABI3); CONTAINS InterPro DOMAIN/s: Transcriptional factor B3 (InterPro:IPR003340); BEST Arabidopsis thaliana protein match is: AP2/B3-like transcriptional factor family protein (TAIR:AT3G26790.1); Has 4494 Blast hits to 2758 proteins in 300 species: Archae - 0; Bacteria - 132; Metazoa - 1104; Fungi - 405; Plants - 1155; Viruses - 101; Other Eukaryotes - 1597 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    8997370..9001185
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_113376.4 → NP_189108.1  AP2/B3-like transcriptional factor family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_189108.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A6N2M3, A6N2N0, A6N2P3, O23625, Q01593, Q1EQV9, Q56ZT2, Q570G9
    UniProtKB/TrEMBL
    A0A178VFQ9
    Conserved Domains (1) summary
    cd10015
    Location:570 → 671
    BfiI_C_EcoRII_N_B3; DNA binding domains of BfiI, EcoRII and plant B3 proteins
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q01593.1

Gene LinkOut

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