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AOX1C alternative oxidase 1C [ Arabidopsis thaliana (thale cress) ]

Gene ID: 822384, updated on 18-Sep-2024

Summary

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Official Symbol
AOX1C
Official Full Name
alternative oxidase 1C
Primary source
TAIR:AT3G27620
Locus tag
AT3G27620
See related
Araport:AT3G27620
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
alternative oxidase 1C
Summary
encodes an isoform of alternate oxidase. expressed in all tissues examined and expression is not induced by antimycin A, an inhibitor of complex III in the mitochondrial respiratory chain.
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Genomic context

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See AOX1C in Genome Data Viewer
Location:
chromosome: 3
Exon count:
4
Sequence:
Chromosome: 3; NC_003074.8 (10229045..10230707, complement)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene SWAP (Suppressor-of-White-APricot)/surp RNA-binding domain-containing protein Neighboring gene Nucleotidylyl transferase superfamily protein Neighboring gene cyclin-dependent kinase inhibitor SMR3-like protein Neighboring gene Transducin/WD40 repeat-like superfamily protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Characterization of the gene family for alternative oxidase from Arabidopsis thaliana. Saisho D, et al. Plant Mol Biol, 1997 Nov. PMID 9349280
  2. Alternative Oxidase Isoforms Are Differentially Activated by Tricarboxylic Acid Cycle Intermediates. Selinski J, et al. Plant Physiol, 2018 Feb. PMID 29208641, Free PMC Article
  3. Analysis of Posttranslational Activation of Alternative Oxidase Isoforms. Selinski J, et al. Plant Physiol, 2017 Aug. PMID 28596420, Free PMC Article
  4. Functional Relationship of Arabidopsis AOXs and PTOX Revealed via Transgenic Analysis. Wang D, et al. Front Plant Sci, 2021. PMID 34367216, Free PMC Article
  5. Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins. Heazlewood JL, et al. Plant Cell, 2004 Jan. PMID 14671022, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. AOX1C activation by Tricarboxylic acid cycle Intermediates.
    Title: Alternative Oxidase Isoforms Are Differentially Activated by Tricarboxylic Acid Cycle Intermediates.
  2. AOX isoforms are differentially activated and that activation at CysI and CysII is additive.
    Title: Analysis of Posttranslational Activation of Alternative Oxidase Isoforms.
Submit: New GeneRIF Correction

General gene information

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NM_113678.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables alternative oxidase activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables superoxide-generating NADPH oxidase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables ubiquinol:oxygen oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in mitochondrion HDA PubMed 
located_in mitochondrion IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrion ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
alternative oxidase 1C
NP_189399.1
  • alternative oxidase 1C (AOX1C); CONTAINS InterPro DOMAIN/s: Alternative oxidase (InterPro:IPR002680); BEST Arabidopsis thaliana protein match is: alternative oxidase 1B (TAIR:AT3G22360.1); Has 1310 Blast hits to 1304 proteins in 245 species: Archae - 0; Bacteria - 111; Metazoa - 12; Fungi - 192; Plants - 384; Viruses - 0; Other Eukaryotes - 611 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    10229045..10230707 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_113678.3 → NP_189399.1  alternative oxidase 1C [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_189399.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O22048
    UniProtKB/TrEMBL
    A0A654FBA7, A0A7G2ETS7
    Conserved Domains (1) summary
    PLN02478
    Location:5 → 329
    PLN02478; alternative oxidase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O22048.1

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