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WNK5 with no lysine (K) kinase 5 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 824326, updated on 18-Sep-2024

Summary

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Official Symbol
WNK5
Official Full Name
with no lysine (K) kinase 5
Primary source
TAIR:AT3G51630
Locus tag
AT3G51630
See related
Araport:AT3G51630
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATWNK5; with no lysine (K) kinase 5; ZIK1
Summary
Encodes a member of the WNK family (9 members in all) of protein kinases, the structural design of which is clearly distinct from those of other known protein kinases, such as receptor-like kinases and mitogen-activated protein kinases.
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Genomic context

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See WNK5 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
7
Sequence:
Chromosome: 3; NC_003074.8 (19148871..19152193)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene ATP-dependent helicase/deoxyribonuclease subunit B Neighboring gene PAP/OAS1 substrate-binding domain superfamily Neighboring gene miscRNA Neighboring gene stress response NST1-like protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The plant WNK gene family and regulation of flowering time in Arabidopsis. Wang Y, et al. Plant Biol (Stuttg), 2008 Sep. PMID 18761494
  2. Compilation and characterization of a novel WNK family of protein kinases in Arabiodpsis thaliana with reference to circadian rhythms. Nakamichi N, et al. Biosci Biotechnol Biochem, 2002 Nov. PMID 12506983
  3. Toward an interaction map of the two-component signaling pathway of Arabidopsis thaliana. Dortay H, et al. J Proteome Res, 2008 Sep. PMID 18642946
  4. MAPK target networks in Arabidopsis thaliana revealed using functional protein microarrays. Popescu SC, et al. Genes Dev, 2009 Jan 1. PMID 19095804, Free PMC Article
  5. Extensive signal integration by the phytohormone protein network. Altmann M, et al. Nature, 2020 Jul. PMID 32612234

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Miscellaneous features

  • Loc: 19149198-19149386 AT3G51630.uORF1
NM_001203127.1
NM_115022.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein histidine kinase binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein kinase activity TAS
Traceable Author Statement
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within photoperiodism, flowering IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within protein phosphorylation TAS
Traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
with no lysine (K) kinase 5
NP_001190056.1
  • with no lysine (K) kinase 5 (WNK5); CONTAINS InterPro DOMAIN/s: Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: with no lysine (K) kinase 4 (TAIR:AT5G58350.1).
NP_566954.2
  • with no lysine (K) kinase 5 (WNK5); CONTAINS InterPro DOMAIN/s: Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: with no lysine (K) kinase 4 (TAIR:AT5G58350.1); Has 105080 Blast hits to 104081 proteins in 3160 species: Archae - 97; Bacteria - 11520; Metazoa - 36773; Fungi - 10256; Plants - 28915; Viruses - 396; Other Eukaryotes - 17123 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    19148871..19152193
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001203127.1 → NP_001190056.1  with no lysine (K) kinase 5 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001190056.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9SCU5, Q9XFS5
    UniProtKB/TrEMBL
    A0A5S9XJV8, A0A654FEX2
    Conserved Domains (2) summary
    cd13983
    Location:23 → 283
    STKc_WNK; Catalytic domain of the Serine/Threonine kinase, With No Lysine (WNK) kinase
    pfam12202
    Location:357 → 398
    OSR1_C; Oxidative-stress-responsive kinase 1 C-terminal domain

  2. NM_115022.3 → NP_566954.2  with no lysine (K) kinase 5 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_566954.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9SCU5, Q9XFS5
    UniProtKB/TrEMBL
    A0A5S9XJV8, A0A654FEX2
    Conserved Domains (2) summary
    cd13983
    Location:23 → 283
    STKc_WNK; Catalytic domain of the Serine/Threonine kinase, With No Lysine (WNK) kinase
    pfam12202
    Location:357 → 398
    OSR1_C; Oxidative-stress-responsive kinase 1 C-terminal domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9SCU5.2

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