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TPI triosephosphate isomerase [ Arabidopsis thaliana (thale cress) ]

Gene ID: 824710, updated on 18-Sep-2024

Summary

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Official Symbol
TPI
Official Full Name
triosephosphate isomerase
Primary source
TAIR:AT3G55440
Locus tag
AT3G55440
See related
Araport:AT3G55440
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATCTIMC; CYTOSOLIC ISOFORM TRIOSE PHOSPHATE ISOMERASE; CYTOSOLIC TRIOSE PHOSPHATE ISOMERASE; CYTOTPI; triosephosphate isomerase; TRIOSEPHOSPHATE ISOMERASE
Summary
Encodes triosephosphate isomerase.
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Genomic context

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See TPI in Genome Data Viewer
Location:
chromosome: 3
Exon count:
9
Sequence:
Chromosome: 3; NC_003074.8 (20553403..20556560)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene O-Glycosyl hydrolases family 17 protein Neighboring gene PBS1-like 1 Neighboring gene SC35-like splicing factor 30

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The sugar-metabolic enzymes aldolase and triose-phosphate isomerase are targets of glutathionylation in Arabidopsis thaliana: detection using biotinylated glutathione. Ito H, et al. Plant Cell Physiol, 2003 Jul. PMID 12881492
  2. The plastid isoform of triose phosphate isomerase is required for the postgerminative transition from heterotrophic to autotrophic growth in Arabidopsis. Chen M, et al. Plant Cell, 2010 Jan. PMID 20097871, Free PMC Article
  3. Enzymes of glycolysis are functionally associated with the mitochondrion in Arabidopsis cells. Giegé P, et al. Plant Cell, 2003 Sep. PMID 12953116, Free PMC Article
  4. Identification of zinc-responsive proteins in the roots of Arabidopsis thaliana using a highly improved method of two-dimensional electrophoresis. Fukao Y, et al. Plant Cell Physiol, 2009 Dec. PMID 19880396
  5. The Extra-Pathway Interactome of the TCA Cycle: Expected and Unexpected Metabolic Interactions. Zhang Y, et al. Plant Physiol, 2018 Jul. PMID 29794018, Free PMC Article

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Reduction of plastid TPI activity results in the buildup of glycerol, glycerol-3-phosphate, dihydroxyacetone phosphate, and methylglyoxal following seed germination.
    Title: The plastid isoform of triose phosphate isomerase is required for the postgerminative transition from heterotrophic to autotrophic growth in Arabidopsis.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_115402.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables copper ion binding HDA PubMed 
enables triose-phosphate isomerase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within carbohydrate metabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in gluconeogenesis IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within glycolytic process IC
Inferred by Curator
more info
 PubMed 
involved_in glycolytic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within response to zinc ion IEP
Inferred from Expression Pattern
more info
 PubMed 
Component Evidence Code Pubs
NOT located_in Golgi apparatus RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
located_in apoplast HDA PubMed 
located_in chloroplast HDA PubMed 
located_in chloroplast stroma HDA PubMed 
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  
located_in cytosol HDA PubMed 
located_in mitochondrion HDA PubMed 
located_in mitochondrion IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plant-type cell wall HDA PubMed 
located_in plant-type vacuole HDA PubMed 
located_in plasma membrane HDA PubMed 
located_in plasmodesma HDA PubMed 

General protein information

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Preferred Names
triosephosphate isomerase
NP_191104.1
  • triosephosphate isomerase (TPI); FUNCTIONS IN: triose-phosphate isomerase activity, copper ion binding; INVOLVED IN: in 7 processes; LOCATED IN: in 8 components; EXPRESSED IN: 27 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Triosephosphate isomerase, active site (InterPro:IPR020861), Aldolase-type TIM barrel (InterPro:IPR013785), Triosephosphate isomerase (InterPro:IPR000652); BEST Arabidopsis thaliana protein match is: triosephosphate isomerase (TAIR:AT2G21170.1); Has 11466 Blast hits to 11464 proteins in 3595 species: Archae - 48; Bacteria - 6204; Metazoa - 1205; Fungi - 243; Plants - 477; Viruses - 0; Other Eukaryotes - 3289 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    20553403..20556560
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_115402.4 → NP_191104.1  triosephosphate isomerase [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_191104.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P48491, Q9M2T5
    UniProtKB/TrEMBL
    A0A178VM57, A0A5S9XL15
    Conserved Domains (1) summary
    PLN02561
    Location:1 → 253
    PLN02561; triosephosphate isomerase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P48491.2

Gene LinkOut

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