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IPMI1 isopropylmalate isomerase 1 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 825068, updated on 18-Sep-2024

Summary

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Official Symbol
IPMI1
Official Full Name
isopropylmalate isomerase 1
Primary source
TAIR:AT3G58990
Locus tag
AT3G58990
See related
Araport:AT3G58990
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
isopropylmalate isomerase 1
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Genomic context

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See IPMI1 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
1
Sequence:
Chromosome: 3; NC_003074.8 (21797058..21798303, complement)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene miscRNA Neighboring gene F-box family protein Neighboring gene F-box/RNI-like superfamily protein Neighboring gene pectin methylesterase 61

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. In Arabidopsis thaliana Substrate Recognition and Tissue- as Well as Plastid Type-Specific Expression Define the Roles of Distinct Small Subunits of Isopropylmalate Isomerase. Lächler K, et al. Front Plant Sci, 2020. PMID 32612621, Free PMC Article
  2. Functional specification of Arabidopsis isopropylmalate isomerases in glucosinolate and leucine biosynthesis. He Y, et al. Plant Cell Physiol, 2010 Sep. PMID 20663849
  3. The plastidic bile acid transporter 5 is required for the biosynthesis of methionine-derived glucosinolates in Arabidopsis thaliana. Gigolashvili T, et al. Plant Cell, 2009 Jun. PMID 19542295, Free PMC Article
  4. A proteomic strategy for global analysis of plant protein complexes. Aryal UK, et al. Plant Cell, 2014 Oct. PMID 25293756, Free PMC Article
  5. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

NM_115761.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables 3-isopropylmalate dehydratase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in L-leucine biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in glucosinolate biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in chloroplast HDA PubMed 
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
located_in chloroplast stroma IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plastid IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
isopropylmalate isomerase 1
NP_191458.1
  • isopropylmalate isomerase 1 (IPMI1); FUNCTIONS IN: hydro-lyase activity, 3-isopropylmalate dehydratase activity; INVOLVED IN: leucine biosynthetic process, metabolic process; LOCATED IN: plastid; EXPRESSED IN: 19 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: 3-isopropylmalate dehydratase, small subunit-like (InterPro:IPR012305), Aconitase A/isopropylmalate dehydratase small subunit, swivel (InterPro:IPR000573), Aconitase/3-isopropylmalate dehydratase, swivel (InterPro:IPR015928), Aconitase-like core (InterPro:IPR015937); BEST Arabidopsis thaliana protein match is: Aconitase/3-isopropylmalate dehydratase protein (TAIR:AT2G43090.1); Has 8940 Blast hits to 8939 proteins in 2288 species: Archae - 372; Bacteria - 5509; Metazoa - 6; Fungi - 358; Plants - 71; Viruses - 0; Other Eukaryotes - 2624 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    21797058..21798303 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_115761.3 → NP_191458.1  isopropylmalate isomerase 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_191458.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9LYT7
    UniProtKB/TrEMBL
    A0A178VAQ3, A0A5S9XNV5, A0A654FJ39
    Conserved Domains (1) summary
    PLN00072
    Location:1 → 253
    PLN00072; 3-isopropylmalate isomerase/dehydratase small subunit; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9LYT7.1

Gene LinkOut

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