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CPK23 calcium-dependent protein kinase 23 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 825809, updated on 18-Sep-2024

Summary

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Official Symbol
CPK23
Official Full Name
calcium-dependent protein kinase 23
Primary source
TAIR:AT4G04740
Locus tag
AT4G04740
See related
Araport:AT4G04740
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATCPK23; calcium-dependent protein kinase 23; T4B21.15; T4B21_15
Summary
member of Calcium Dependent Protein Kinase
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Genomic context

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See CPK23 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
10
Sequence:
Chromosome: 4; NC_003075.7 (2402897..2408737, complement)

Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene calcium-dependent protein kinase 21 Neighboring gene Ta11-like non-LTR retrotransposon Neighboring gene uncharacterized protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Calcium elevation-dependent and attenuated resting calcium-dependent abscisic acid induction of stomatal closure and abscisic acid-induced enhancement of calcium sensitivities of S-type anion and inward-rectifying K channels in Arabidopsis guard cells. Siegel RS, et al. Plant J, 2009 Jul. PMID 19302418, Free PMC Article
  2. ABI1 of Arabidopsis is a protein serine/threonine phosphatase highly regulated by the proton and magnesium ion concentration. Leube MP, et al. FEBS Lett, 1998 Mar 6. PMID 9537523
  3. Plasma membrane-associated calcium signaling modulates cadmium transport. Zhang Y, et al. New Phytol, 2023 Apr. PMID 36567524
  4. Ca(2+)-dependent phosphorylation of NRAMP1 by CPK21 and CPK23 facilitates manganese uptake and homeostasis in Arabidopsis. Fu D, et al. Proc Natl Acad Sci U S A, 2022 Oct 4. PMID 36161952, Free PMC Article
  5. Guard cell anion channel SLAC1 is regulated by CDPK protein kinases with distinct Ca2+ affinities. Geiger D, et al. Proc Natl Acad Sci U S A, 2010 Apr 27. PMID 20385816, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Calcium-dependent protein kinases CPK21 and CPK23 phosphorylate and activate the iron-regulated transporter IRT1 to regulate iron deficiency in Arabidopsis.
    Title: Calcium-dependent protein kinases CPK21 and CPK23 phosphorylate and activate the iron-regulated transporter IRT1 to regulate iron deficiency in Arabidopsis.
  2. Plasma membrane-associated calcium signaling modulates cadmium transport.
    Title: Plasma membrane-associated calcium signaling modulates cadmium transport.
  3. Ca(2+)-dependent phosphorylation of NRAMP1 by CPK21 and CPK23 facilitates manganese uptake and homeostasis in Arabidopsis.
    Title: Ca(2+)-dependent phosphorylation of NRAMP1 by CPK21 and CPK23 facilitates manganese uptake and homeostasis in Arabidopsis.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_001203743.2
NM_001340501.1
NM_001340502.1
NM_001340503.1
NM_001340504.1
NM_001340505.1
NM_001340506.1

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein kinase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein phosphatase binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within regulation of stomatal movement IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within regulation of stomatal movement NAS
Non-traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within response to abscisic acid IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within response to abscisic acid NAS
Non-traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
calcium-dependent protein kinase 23
NP_001190672.1
  • calcium-dependent protein kinase 23 (CPK23); FUNCTIONS IN: in 6 functions; INVOLVED IN: protein amino acid phosphorylation; EXPRESSED IN: 17 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: EF-Hand 1, calcium-binding site (InterPro:IPR018247), Serine/threonine-protein kinase domain (InterPro:IPR002290), EF-hand-like domain (InterPro:IPR011992), Calcium-binding EF-hand (InterPro:IPR002048), EF-hand (InterPro:IPR018248), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Protein kinase, catalytic domain (InterPro:IPR000719), EF-HAND 2 (InterPro:IPR018249), Calcium-dependent protein kinase (InterPro:IPR020642), Tyrosine-protein kinase, catalytic domain (InterPro:IPR020635), Calcium/calmodulin-dependent protein kinase-like (InterPro:IPR020636); BEST Arabidopsis thaliana protein match is: calcium-dependent protein kinase 21 (TAIR:AT4G04720.1).
NP_001319868.1
  • calcium-dependent protein kinase 23 (CPK23); FUNCTIONS IN: in 6 functions; INVOLVED IN: response to cadmium ion, protein amino acid phosphorylation, N-terminal protein myristoylation; EXPRESSED IN: 18 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: EF-Hand 1, calcium-binding site (InterPro:IPR018247), Serine/threonine-protein kinase domain (InterPro:IPR002290), EF-hand-like domain (InterPro:IPR011992), Calcium-binding EF-hand (InterPro:IPR002048), EF-hand (InterPro:IPR018248), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Protein kinase, catalytic domain (InterPro:IPR000719), EF-HAND 2 (InterPro:IPR018249), Calcium-dependent protein kinase (InterPro:IPR020642), Calcium/calmodulin-dependent protein kinase-like (InterPro:IPR020636); BEST Arabidopsis thaliana protein match is: calcium-dependent protein kinase 21 (TAIR:AT4G04720.1); Has 128755 Blast hits to 122983 proteins in 3953 species: Archae - 178; Bacteria - 14151; Metazoa - 46216; Fungi - 17196; Plants - 28127; Viruses - 447; Other Eukaryotes - 22440 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003075.7 Reference assembly

    Range
    2402897..2408737 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001340501.1 → NP_001319868.1  calcium-dependent protein kinase 23 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9M101, Q9ZSA0
    UniProtKB/TrEMBL
    A0A7G2EXQ4

  2. NM_001340502.1 → NP_001328084.1  calcium-dependent protein kinase 23 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9M101, Q9ZSA0
    UniProtKB/TrEMBL
    A0A7G2EXQ4

  3. NM_001340503.1 → NP_001328085.1  calcium-dependent protein kinase 23 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9M101, Q9ZSA0
    UniProtKB/TrEMBL
    A0A7G2EXQ4

  4. NM_001340504.1 → NP_001328083.1  calcium-dependent protein kinase 23 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9M101, Q9ZSA0
    UniProtKB/TrEMBL
    A0A7G2EXQ4

  5. NM_001203743.2 → NP_001190672.1  calcium-dependent protein kinase 23 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001190672.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A7G2EXQ4, F4JGW8
    Conserved Domains (4) summary
    smart00220
    Location:84 → 327
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd00051
    Location:374 → 433
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd05117
    Location:82 → 326
    STKc_CAMK; The catalytic domain of CAMK family Serine/Threonine Kinases
    pfam13499
    Location:374 → 433
    EF-hand_7; EF-hand domain pair

  6. NM_001340505.1 → NP_001328081.1  calcium-dependent protein kinase 23 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9M101, Q9ZSA0
    UniProtKB/TrEMBL
    A0A7G2EXQ4

  7. NM_001340506.1 → NP_001328082.1  calcium-dependent protein kinase 23 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9M101, Q9ZSA0
    UniProtKB/TrEMBL
    A0A7G2EXQ4
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9M101.1

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