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CRK5 cysteine-rich RLK (RECEPTOR-like protein kinase) 5 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 828412, updated on 18-Sep-2024

Summary

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Official Symbol
CRK5
Official Full Name
cysteine-rich RLK (RECEPTOR-like protein kinase) 5
Primary source
TAIR:AT4G23130
Locus tag
AT4G23130
See related
Araport:AT4G23130
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
cysteine-rich RLK (RECEPTOR-like protein kinase) 5; F7H19.320; F7H19_320; RECEPTOR-LIKE PROTEIN KINASE 6; RLK6
Summary
Encodes a receptor-like protein kinase. Naming convention from Chen et al 2003 (PMID 14756307)
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Genomic context

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See CRK5 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
7
Sequence:
Chromosome: 4; NC_003075.7 (12117491..12120220, complement)

Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene insulin-like growth factor binding protein Neighboring gene Bromo-adjacent homology (BAH) domain-containing protein Neighboring gene cysteine-rich RLK (RECEPTOR-like protein kinase) 6 Neighboring gene cysteine-rich RLK (RECEPTOR-like protein kinase) 7

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Overexpression of an Arabidopsis cysteine-rich receptor-like protein kinase, CRK5, enhances abscisic acid sensitivity and confers drought tolerance. Lu K, et al. J Exp Bot, 2016 Sep. PMID 27406784, Free PMC Article
  2. Cysteine-rich receptor-like kinase CRK5 as a regulator of growth, development, and ultraviolet radiation responses in Arabidopsis thaliana. Burdiak P, et al. J Exp Bot, 2015 Jun. PMID 25969551, Free PMC Article
  3. The AtCRK5 Protein Kinase Is Required to Maintain the ROS NO Balance Affecting the PIN2-Mediated Root Gravitropic Response in Arabidopsis. Cséplő Á, et al. Int J Mol Sci, 2021 Jun 1. PMID 34205973, Free PMC Article
  4. Inactivation of plasma membrane-localized CDPK-RELATED KINASE5 decelerates PIN2 exocytosis and root gravitropic response in Arabidopsis. Rigó G, et al. Plant Cell, 2013 May. PMID 23673979, Free PMC Article
  5. Activation of hypersensitive cell death by pathogen-induced receptor-like protein kinases from Arabidopsis. Chen K, et al. Plant Mol Biol, 2004 Sep. PMID 15604743

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The AtCRK5 Protein Kinase Is Required to Maintain the ROS NO Balance Affecting the PIN2-Mediated Root Gravitropic Response in Arabidopsis.
    Title: The AtCRK5 Protein Kinase Is Required to Maintain the ROS NO Balance Affecting the PIN2-Mediated Root Gravitropic Response in Arabidopsis.
  2. overexpression enhances abscisic acid sensitivity and confers drought tolerance
    Title: Overexpression of an Arabidopsis cysteine-rich receptor-like protein kinase, CRK5, enhances abscisic acid sensitivity and confers drought tolerance.
  3. CRK5 plays an essential role in the regulation of growth, development, and acclimatory responses in Arabidopsis thaliana.
    Title: Cysteine-rich receptor-like kinase CRK5 as a regulator of growth, development, and ultraviolet radiation responses in Arabidopsis thaliana.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_001341575.1
NM_118442.4
NM_179094.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables kinase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within defense response to bacterium IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within programmed cell death IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within response to salicylic acid IEP
Inferred from Expression Pattern
more info
 PubMed 
Component Evidence Code Pubs
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
located_in plasma membrane ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
cysteine-rich RLK (RECEPTOR-like protein kinase) 5
NP_567677.1
  • cysteine-rich RLK (RECEPTOR-like protein kinase) 5 (CRK5); FUNCTIONS IN: kinase activity; INVOLVED IN: defense response to bacterium, programmed cell death, response to salicylic acid stimulus; LOCATED IN: endomembrane system; EXPRESSED IN: 9 plant structures; EXPRESSED DURING: 8 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Serine/threonine-protein kinase domain (InterPro:IPR002290), Protein of unknown function DUF26 (InterPro:IPR002902), Serine-threonine/tyrosine-protein kinase (InterPro:IPR001245), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Protein kinase-like domain (InterPro:IPR011009), Protein kinase, catalytic domain (InterPro:IPR000719), Tyrosine-protein kinase, catalytic domain (InterPro:IPR020635); BEST Arabidopsis thaliana protein match is: cysteine-rich RLK (RECEPTOR-like protein kinase) 4 (TAIR:AT3G45860.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
NP_849425.1
  • cysteine-rich RLK (RECEPTOR-like protein kinase) 5 (CRK5); FUNCTIONS IN: kinase activity; INVOLVED IN: defense response to bacterium, programmed cell death, response to salicylic acid stimulus; LOCATED IN: endomembrane system; EXPRESSED IN: 9 plant structures; EXPRESSED DURING: 8 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Protein of unknown function DUF26 (InterPro:IPR002902), Serine-threonine/tyrosine-protein kinase (InterPro:IPR001245), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: cysteine-rich RLK (RECEPTOR-like protein kinase) 4 (TAIR:AT3G45860.1); Has 121629 Blast hits to 120099 proteins in 4447 species: Archae - 100; Bacteria - 13629; Metazoa - 44864; Fungi - 10560; Plants - 34243; Viruses - 400; Other Eukaryotes - 17833 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003075.7 Reference assembly

    Range
    12117491..12120220 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_118442.4 → NP_567677.1  cysteine-rich RLK (RECEPTOR-like protein kinase) 5 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_567677.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O65465, Q8H1S3, Q9C5S8
    UniProtKB/TrEMBL
    A0A654FRY3
    Conserved Domains (3) summary
    smart00221
    Location:345 → 612
    STYKc; Protein kinase; unclassified specificity
    cd14066
    Location:346 → 613
    STKc_IRAK; Catalytic domain of the Serine/Threonine kinases, Interleukin-1 Receptor Associated Kinases and related STKs
    pfam01657
    Location:35 → 128
    Stress-antifung; Salt stress response/antifungal

  2. NM_179094.3 → NP_849425.1  cysteine-rich RLK (RECEPTOR-like protein kinase) 5 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_849425.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A5S9XVH5, A0A654FRY3
    Conserved Domains (2) summary
    cd14066
    Location:350 → 617
    STKc_IRAK; Catalytic domain of the Serine/Threonine kinases, Interleukin-1 Receptor Associated Kinases and related STKs
    pfam01657
    Location:37 → 128
    Stress-antifung; Salt stress response/antifungal

  3. NM_001341575.1 → NP_001329890.1  cysteine-rich RLK (RECEPTOR-like protein kinase) 5 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8B944, A0A654FRY3
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9C5S8.1

Gene LinkOut

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